Circulatory

Circulatory, Respiratory

High-risk pulmonary embolism: the significance and perspectives of pulmonary reperfusion

Summary This editorial explores the current landscape of pulmonary reperfusion strategies in patients with high-risk pulmonary embolism (PE). It underscores the centrality of rapid hemodynamic stabilization and reperfusion in managing high-risk PE and analyzes recent data from a large target trial emulation by Stadlbauer et al. The authors conclude that while systemic thrombolysis (SYS) remains […]

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Circulatory

Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest

Summary of “Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest” Abstract Summary: Extracorporeal cardiopulmonary resuscitation (ECPR), using venoarterial ECMO during refractory cardiac arrest, can restore circulation and improve outcomes compared with conventional CPR (CCPR) alone. While evidence suggests ECPR enhances survival with favorable neurological recovery, its complexity, resource demands, costs, and complication risks restrict widespread use.

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Circulatory

The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations

Summary of The Predictive Value of Highly Malignant EEG Patterns After Cardiac Arrest: Evaluation of the ERC-ESICM Recommendations Abstract Highly malignant EEG patterns (HMEP), specifically suppression and burst-suppression, are recommended by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) for predicting poor neurological outcomes after cardiac arrest. This study,

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The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations Read Post »

Circulatory, Respiratory

Managing Refractory Hypoxemia in ARDS Obese Patients with Veno-Venous Extra-Corporeal Membrane Oxygenation: A Narrative Review

Abstract Veno-venous extracorporeal membrane oxygenation (vvECMO) is a life-saving intervention for severe respiratory failure unresponsive to conventional therapies. However, managing refractory hypoxemia in morbidly obese patients poses significant challenges due to the unique physiological characteristics of this population, including hyperdynamic circulation, elevated cardiac output, and increased oxygen consumption. These factors can limit the effectiveness of

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Managing Refractory Hypoxemia in ARDS Obese Patients with Veno-Venous Extra-Corporeal Membrane Oxygenation: A Narrative Review Read Post »

Circulatory

Recent Advances and Future Directions in Extracorporeal Carbon Dioxide Removal

Summary of “Recent Advances and Future Directions in Extracorporeal Carbon Dioxide Removal” Abstract Extracorporeal carbon dioxide removal (ECCO₂R) is an emerging technique designed to facilitate lung-protective ventilation and reduce the work of breathing by removing CO₂ from venous blood. Operating at lower blood flows than extracorporeal membrane oxygenation (ECMO), ECCO₂R reduces procedural invasiveness but remains

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Circulatory

Immediate Clinical Complications Occurring During Membrane Change in Patients on Veno-Venous Extracorporeal Membrane Oxygenation

Abstract The clinical tolerance of extracorporeal membrane oxygenation (ECMO) membrane changes in acute respiratory distress syndrome (ARDS) patients under veno-venous ECMO (VV-ECMO) has not been reported. The aim of this study was to describe the tolerance of membrane change. Patients requiring VV-ECMO were retrospectively included between March 2020 and May 2022. In case of membrane

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Immediate Clinical Complications Occurring During Membrane Change in Patients on Veno-Venous Extracorporeal Membrane Oxygenation Read Post »

Circulatory

Evolution of Critical Care Cardiology: An Update on Structure, Care Delivery, Training, and Research Paradigms: A Scientific Statement From the American Heart Association

Abstract Critical care cardiology refers to the practice focus of and subspecialty training for the comprehensive management of life-threatening cardiovascular diseases and comorbid conditions that require advanced critical care in an intensive care unit. The development of coronary care units is often credited for a dramatic decline in mortality rates after acute myocardial infarction throughout

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Evolution of Critical Care Cardiology: An Update on Structure, Care Delivery, Training, and Research Paradigms: A Scientific Statement From the American Heart Association Read Post »

Circulatory

Hemodynamic Impact of the Trendelenburg Position: A Systematic Review and Meta-analysis

Abstract Objective To systematically evaluate the impact of the Trendelenburg position on hemodynamic parameters in adult patients. Design Systematic literature review and meta-analysis using PubMed and Medline. Setting All prospective interventional studies comparing the hemodynamic characteristics of patients in the horizontal supine position and Trendelenburg position. Measurements and main results A total of 16 studies

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Circulatory, Respiratory

Acute lung injury and post-cardiac arrest syndrome: a narrative review

Abstract Background Post-cardiac arrest syndrome (PCAS) presents a multifaceted challenge in clinical practice, characterized by severe neurological injury and high mortality rates despite advancements in management strategies. One of the important critical aspects of PCAS is post-arrest lung injury (PALI), which significantly contributes to poor outcomes. PALI arises from a complex interplay of pathophysiological mechanisms,

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Circulatory

Management of Hemorrhagic Shock: Physiology Approach, Timing and Strategies

Abstract Hemorrhagic shock (HS) management is based on a timely, rapid, definitive source control of bleeding/s and on blood loss replacement. Stopping the hemorrhage from progressing from any named and visible vessel is the main stem fundamental praxis of efficacy and effectiveness and an essential, obligatory, life-saving step. Blood loss replacement serves the purpose of

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