VV-ecmo

Circulatory, Respiratory

Physiological and clinical effects of two ultraprotective ventilation strategies in patients with VV-ECMO: the ECMOVENT study

ECMOVENT: Comparing Two Ultraprotective Ventilation Strategies on VV-ECMO Abstract: The optimal ventilatory strategy for ARDS patients on VV-ECMO remains debated. This single-center, before-and-after study compared two ultraprotective approaches: VT1 strategy: Assist-controlled volume mode, VT 1 ml/kg PBW, RR 5/min, Pplat 20–25 cmH₂O. ΔP8 strategy: Pressure-controlled mode, ΔP 8 cmH₂O, PEEP 14 cmH₂O, RR 10/min. Among […]

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Cardiovascular, Respiratory

Awake vs. Sedated Cannulation for Extra-Corporeal Membrane Oxygenation in Patients with COVID-19 Induced Acute Respiratory Distress Syndrome

Why this article matters   Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is routinely initiated in patients with severe ARDS after intubation, deep sedation, and often neuromuscular blockade. During the COVID-19 pandemic, however, some centers explored an alternative strategy: awake ECMO cannulation, in which patients are cannulated while spontaneously breathing and supported without invasive mechanical ventilation. The

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Awake vs. Sedated Cannulation for Extra-Corporeal Membrane Oxygenation in Patients with COVID-19 Induced Acute Respiratory Distress Syndrome Read Post »

Uncategorized

Prone positioning during veno-venous extracorporeal membrane oxygenation: a systematic review and meta-analysis

Summary Pettenuzzo et al. conducted a comprehensive systematic review and meta-analysis evaluating the effects of prone positioning during veno-venous extracorporeal membrane oxygenation (V-V ECMO) in patients with acute hypoxemic respiratory failure. Analyzing data from 22 studies (3,465 patients), the review concluded that prone positioning is associated with significantly improved 28-day and hospital mortality rates despite

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Prone positioning during veno-venous extracorporeal membrane oxygenation: a systematic review and meta-analysis Read Post »

Cardiovascular, Pulmonary

Right Ventricular Function in ARDS: Impact on Outcome, Respiratory Strategy and Use of VV-ECMO

Summary of Right Ventricular Function in Acute Respiratory Distress Syndrome: Impact on Outcome, Respiratory Strategy and Use of Veno-Venous Extracorporeal Membrane Oxygenation Abstract Summary: Petit et al. explore the pathophysiology of right ventricular (RV) dysfunction in Acute Respiratory Distress Syndrome (ARDS), emphasizing its significant impact on patient outcomes. The authors propose an RV-protective management strategy

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Right Ventricular Function in ARDS: Impact on Outcome, Respiratory Strategy and Use of VV-ECMO Read Post »

Circulatory, Respiratory

Managing Refractory Hypoxemia in ARDS Obese Patients with Veno-Venous Extra-Corporeal Membrane Oxygenation: A Narrative Review

Abstract Veno-venous extracorporeal membrane oxygenation (vvECMO) is a life-saving intervention for severe respiratory failure unresponsive to conventional therapies. However, managing refractory hypoxemia in morbidly obese patients poses significant challenges due to the unique physiological characteristics of this population, including hyperdynamic circulation, elevated cardiac output, and increased oxygen consumption. These factors can limit the effectiveness of

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Managing Refractory Hypoxemia in ARDS Obese Patients with Veno-Venous Extra-Corporeal Membrane Oxygenation: A Narrative Review Read Post »

Circulatory

Immediate Clinical Complications Occurring During Membrane Change in Patients on Veno-Venous Extracorporeal Membrane Oxygenation

Abstract The clinical tolerance of extracorporeal membrane oxygenation (ECMO) membrane changes in acute respiratory distress syndrome (ARDS) patients under veno-venous ECMO (VV-ECMO) has not been reported. The aim of this study was to describe the tolerance of membrane change. Patients requiring VV-ECMO were retrospectively included between March 2020 and May 2022. In case of membrane

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Immediate Clinical Complications Occurring During Membrane Change in Patients on Veno-Venous Extracorporeal Membrane Oxygenation Read Post »

Uncategorized

Setting and Monitoring of Mechanical Ventilation During Venovenous ECMO

Abstract This review provides insights into the management of mechanical ventilation during venovenous extracorporeal membrane oxygenation (VV-ECMO) for severe acute respiratory distress syndrome (ARDS). It focuses on strategies to minimize ventilator-induced lung injury (VILI) by employing ultra-lung-protective ventilation, exploring key parameters like tidal volume, plateau pressure, and driving pressure. Key Points Lung Rest Strategy: VV-ECMO

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Setting and Monitoring of Mechanical Ventilation During Venovenous ECMO Read Post »

Circulatory

The effects of blood cell salvage on transfusion requirements after decannulation from veno-venous extracorporeal membrane oxygenation: an emulated trial analysis

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a supportive therapy for acute respiratory failure with increased risk of packed red blood cells (PRBC) transfusion. Blood cell salvage (BCS) aims to reduce blood transfusion, but its efficacy is unclear. This study aimed to estimate the effect of BCS at the time of removal of the

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The effects of blood cell salvage on transfusion requirements after decannulation from veno-venous extracorporeal membrane oxygenation: an emulated trial analysis Read Post »

Circulatory

Anticoagulation management during veno-venous ECMO support because of ARDS: Single-center experience

Abstract   Background Patients with severe acute respiratory distress syndrome (ARDS) show a high mortality rate of up to 60 %. In such cases, extracorporeal membrane oxygenation (ECMO) support is often required, which would necessitate anticoagulation therapy, predominantly with heparin. Some bleeding events occurred more frequently in patients during the COVID-19 pandemic who were on venovenous

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Anticoagulation management during veno-venous ECMO support because of ARDS: Single-center experience Read Post »

Circulatory

ECMO-weaning facilitated by neurally adjusted ventilatory assist (NAVA): a case for principal clarification

Abstract The use of veno-venous extracorporeal membrane oxygenation (VV-ECMO) has become increasingly prevalent, particularly in respiratory disease pandemics such as H1N1-influenza and SARS-CoV-2. This surge has emphasized the importance of clear therapy recommendations, improved accessibility to ECMO technology, established ECMO teams, and structured networks to ensure access to specialized care throughout the course of the

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ECMO-weaning facilitated by neurally adjusted ventilatory assist (NAVA): a case for principal clarification Read Post »

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