Mechanical Ventilation

Mechanical Ventilation, Pharmacological Insights in Critical Care

Pressure support, patient effort and tidal volume: a conceptual model for a non linear interaction

Abstract Pressure support ventilation (PSV) is a form of assisted ventilation which has become frequently used, with the aim of partially unloading the patient’s inspiratory muscles. Both under- and over-assistance should be avoided to target a lung- and diaphragm- protective ventilation. Herein, we propose a conceptual model, supported by actual data, to describe how patient […]

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Mechanical Ventilation, Respiratory

Personalized mechanical ventilation in acute respiratory distress syndrome

Abstract A personalized mechanical ventilation approach for patients with adult respiratory distress syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging, and biological phenotypes may improve ventilation practice and outcome. However, additional research is warranted before personalized mechanical ventilation strategies can be applied at the bedside. Ventilatory parameters should be titrated based

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Mechanical Ventilation

Volatile anesthetics for lung- and diaphragm-protective sedation

Abstract This review explores the complex interactions between sedation and invasive ventilation and examines the potential of volatile anesthetics for lung- and diaphragm-protective sedation. In the early stages of invasive ventilation, many critically ill patients experience insufficient respiratory drive and effort, leading to compromised diaphragm function. Compared with common intravenous agents, inhaled sedation with volatile anesthetics

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Mechanical Ventilation

Ventilator induced lung injury: a case for a larger umbrella?

Summary of “Assessing lung recruitability: does it help with PEEP settings?” This editorial examines the relationship between lung recruitability and the selection of positive end-expiratory pressure (PEEP) settings in acute respiratory distress syndrome (ARDS) management. While recruitability measures the potential to reinflate atelectatic lung regions, PEEP must prevent their collapse while considering additional factors like

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Artificial Intelligence, Mechanical Ventilation

Artificial Intelligence for Mechanical Ventilation: A Transformative Shift in Critical Care

Abstract   With the large volume of data coming from implemented technologies and monitoring systems, intensive care units (ICUs) represent a key area for artificial intelligence (AI) application. Despite the last decade has been marked by studies focused on the use of AI in medicine, its application in mechanical ventilation management is still limited. Optimizing

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Mechanical Ventilation

Predictors of weaning failure in ventilated intensive care patients: a systematic evidence map

Abstract Background Ventilator weaning is of great importance for intensive care patients in order to avoid complications caused by prolonged ventilation. However, not all patients succeed in weaning immediately. Their spontaneous breathing may be insufficient, resulting in extubation failure and the subsequent need for reintubation. To identify patients at high risk for weaning failure, a

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Mechanical Ventilation

Stepwise Ventilator Waveform Assessment to Diagnose Pulmonary Pathophysiology

Electronically displayed ventilator waveforms provide a wealth of insight into the physiology of the respiratory system. Pressure and flow values can be independent variables that reflect control by the ventilator or dependent variables that demonstrate the respiratory system’s response to mechanical ventilation. Diagrams of time-based pressure and flow curves may reveal underlying pathophysiology beyond more

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