Respiratory

Mechanical Ventilation, Respiratory

Revisiting Acute Respiratory Distress Syndrome ventilation management: Time for a paradigm shift focusing on tidal volume

Abstract: Merola and colleagues critically evaluate current Acute Respiratory Distress Syndrome (ARDS) ventilation strategies, emphasizing limitations inherent in universally applying low tidal volume (VT) strategies. They argue for personalized, physiology-driven ventilation approaches that incorporate mechanical power, compliance, and transpulmonary pressures. The authors highlight the complexity and heterogeneity of ARDS, suggesting the inadequacy of global parameters […]

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Respiratory

Physical and respiratory therapy in the critically ill patient with obesity: a narrative review

Abstract: Martínez-Camacho et al. discuss the critical aspects of physical and respiratory therapy for obese patients in the ICU, highlighting the complexities of obesity-related respiratory and metabolic disturbances. They emphasize the importance of early mobilization, meticulous ventilatory management, personalized nutritional support, and multidisciplinary collaboration as pivotal strategies to enhance functional outcomes and reduce complications in

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Respiratory

Lung electrical impedance tomography during positioning, weaning and chest physiotherapy in mechanically ventilated critically ill patients: a…

🫁 Lung EIT in Positioning, Weaning, and Chest Physiotherapy: A Narrative Review Abstract: Electrical impedance tomography (EIT) is a bedside, radiation-free imaging modality that measures ventilation and, with some techniques, perfusion. While most ICU studies have focused on ARDS and PEEP titration, this review explored EIT applications during positioning, weaning, and chest physiotherapy in intubated

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Circulatory, Respiratory

High-risk pulmonary embolism: the significance and perspectives of pulmonary reperfusion

Summary This editorial explores the current landscape of pulmonary reperfusion strategies in patients with high-risk pulmonary embolism (PE). It underscores the centrality of rapid hemodynamic stabilization and reperfusion in managing high-risk PE and analyzes recent data from a large target trial emulation by Stadlbauer et al. The authors conclude that while systemic thrombolysis (SYS) remains

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Respiratory

Peri-intubation complications in critically ill obese patients: a secondary analysis of the international INTUBE cohort

Summary of Peri-intubation complications in critically ill obese patients: a secondary analysis of the international INTUBE cohort (Russotto et al.) Abstract Summary: Russotto et al. conducted a secondary analysis of the INTUBE study, a multicenter international observational cohort, to evaluate peri-intubation adverse events in critically ill obese patients (BMI ≥ 30 kg/m²). They found a

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Respiratory

Driving pressure-guided ventilation decreases the mechanical power compared to predicted body weight-guided ventilation in the ARDS.

Summary of Driving Pressure-Guided Ventilation Decreases the Mechanical Power Compared to Predicted Body Weight-Guided Ventilation in the Acute Respiratory Distress Syndrome (Haudebourg et al.) Abstract Summary: Haudebourg et al. investigated the impact of driving pressure (ΔP)-guided ventilation versus predicted body weight (PBW)-guided ventilation on mechanical power in moderate-to-severe acute respiratory distress syndrome (ARDS) patients. Their

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Driving pressure-guided ventilation decreases the mechanical power compared to predicted body weight-guided ventilation in the ARDS. Read Post »

Respiratory

Machine learning-based identification of efficient and restrictive physiological subphenotypes in acute respiratory distress syndrome

Summary of Machine learning-based identification of efficient and restrictive physiological subphenotypes in acute respiratory distress syndrome (Meza-Fuentes et al.) Abstract Summary: Meza-Fuentes et al. utilized advanced machine learning methodologies to categorize Acute Respiratory Distress Syndrome (ARDS) into two distinct physiological subphenotypes: Efficient and Restrictive. By analyzing ventilatory mechanics and gas exchange parameters collected within the

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Respiratory

Management of Asthma and COPD Exacerbations in Adults in the ICU

Abstract Severe, life-threatening asthma and COPD exacerbations are managed commonly in the ICU and are associated with significant morbidity and mortality. It is important to understand the commonalities and differences in the diagnosis and management of these obstructive lung diseases to improve patient outcomes via evidence-based care. In this review, we first outline triggers of

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Respiratory

Nebuliser therapy in critical care: The past, present and future

Summary of “Nebuliser Therapy in Critical Care: The Past, Present and Future” Abstract Nebuliser therapy, utilizing the efficiency of pulmonary drug absorption, represents a pivotal approach for delivering medications locally and systemically in critically ill patients. This review discusses the historical evolution of nebuliser technologies, the science of aerosol drug delivery, and current practices, emphasizing

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Respiratory

Recent Advances and Future Directions in Extracorporeal Carbon Dioxide Removal

Abstract Extracorporeal carbon dioxide removal (ECCO2R) is an emerging technique designed to reduce carbon dioxide (CO2) levels in venous blood while enabling lung-protective ventilation or alleviating the work of breathing. Unlike high-flow extracorporeal membrane oxygenation (ECMO), ECCO2R operates at lower blood flows (0.4–1.5 L/min), making it less invasive, with smaller cannulas and simpler devices. Despite

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