Tags Archives: donation after circulatory death (DCD)

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Protecting the DCD lung: the importance of inmediate atrial decompression

      Dr.Sam Zeraatian Nejad Davani, Cardiovascular and Thoracic Surgeon, Transplant and Thoracic Organs Recovery Surgeon. Director of Georgia Atlanta Procure on Demand Thoracic Organs Transplant and Procurement Surgery. ..

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Venous first double TA-NRP in extended warm-ischemia DCD

    In Thoracoabdominal Normothermic Regional Perfusion (TA-NRP) for Donation after Circulatory Death (DCD), initiating central cannulation with a venous-first approach serves as a critical step to decompress an acutely..

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Beating Heart Implantation: A Comprehensive Technical Perspective

Abstract Traditional methods of heart transplantation utilizing allografts from donors after circulatory death (DCD) involve 2 periods of ischemia and 2 ischemia reperfusion injuries (IRI). Both ischemia and IRI are..

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Surgical Procurement of a Donor Heart with Complex Congenital and Venous Anomalies

    Surgical Procurement of a Donor Heart with Complex Congenital and Venous Anomalies: PLSVC, Coronary Sinus Dilation, RA Aneurysm, and Patent Ductus Arteriosus (PDA) In thoracic organ transplantation, discovering..

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Partial Heart and Lung Transplantation with Two Recipients from One Donor

    Partial Heart and Lung Transplantation: Maximizing Donor Organ Utilization Through Two-Recipient Transplantation Partial heart and lung transplantation is an innovative organ utilization strategy that allows transplantation of thoracic..

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Managing aortic and pulmonary root enlargement in donor organs

      Managing aortic and pulmonary root enlargement in donor organs requires a meticulous, proactive strategy to ensure structural stability before implantation into an emergency recipient. Utilizing a double..

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Managing complex congenital anomalies during multi-organ donor procurement

    Managing complex congenital anomalies during multi-organ donor procurement requires precise surgical tailoring to preserve the structural integrity of the heart. When faced with a donor harboring both a..

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Total trans septal approach and DCD rapid recovery

  Oxygenated Cardioplegia (OCP) using a blood-based vehicle represents a significant shift from traditional cold crystalloid preservation during multi-organ heart and lung procurements. By leveraging a mixture of oxygenated donor..

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Complex Heart-Lung Procurement and Back-Table Reconstruction

    Navigating the Anatomical Storm: Complex Heart-Lung Procurement and Back-Table Reconstruction   In the high-stakes arena of cardiothoracic transplantation, procurement surgery is often treated as a standardized exercise. Surgeons..

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Procuring organs from a complex donor presenting with a double Azygos system

      Procuring organs from a complex donor presenting with a double Azygos system, anatomically corrected malposition of the great arteries (ACMGA), a hypoplastic left hemithorax, and severe kyphoscoliosis..

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Surgical technique of donation after circulatory death heart procurement using direct procurement and hypothermic oxygenated perfusion preservation

Abstract Introduction Donation after circulatory death (DCD) has re-emerged as a means of expanding the donor heart pool. Current clinical practice relies mainly on direct procurement followed by normothermic machine..

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Retrograde Priming During OCS Cardiac Procurement

Technical Draft and Procedural Overview Introduction Retrograde priming during TransMedics Organ Care System (OCS) Heart cardiac procurement is an advanced perfusion maneuver designed to optimize coronary de-airing, improve myocardial washout,..

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DCD step by Step for Heart and lung donation

      1. Donor Identification •Identify a potential DCD donor (Maastricht category III or II in some systems). •Patient has devastating neurologic or systemic injury but does not meet..

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Normothermic Regional Perfusion in Controlled Donation After Circulatory Death: Growing Evidence for Liver Transplantation

Abstract Normothermic regional perfusion (NRP) has emerged as one of the most consequential innovations in modern liver transplantation, particularly in the context of controlled donation after circulatory death (cDCD). Historically,..

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Consciousness and Controlled Donation After Circulatory Determination of Death

Abstract A recent series of near-misses in which patients scheduled for organ recovery exhibited unexpected signs of consciousness recognized only moments before initiation of surgery has triggered investigations by national bodies. In September 2024, a..

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DCD Heart and Lung Explantation With TransMedics OCS Heart Recovery and EVLP Lung Perfusion

I. PRE-PROCUREMENT PREPARATION (DCD CONTEXT)   1. Donor Selection and Planning •Confirm controlled DCD donor (Maastricht Category III). •Review: •Warm ischemic time (WIT) thresholds •Functional warm ischemia (fWIT) •Hemodynamics prior..

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Cardiac function recovery after 20-min hands-off using thoracoabdominal-normothermic regional perfusion

Abstract Background The increasing prevalence of end-stage heart failure coupled with limited donor organs creates a critical need for novel strategies in heart transplantation. Donation after circulatory death offers a..

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How I Do It: Donation After Circulatory Death With Normothermic Regional Perfusion in Small Babies

Abstract Background: The gold standard for treatment of patients with end-stage heart failure remains . Time spent on the active waiting list, notably for  patients, contributes to alarmingly high mortality. Donation after..

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The Evolving Role of Extracorporeal In Situ Perfusion Technology in Organ Donor Recovery with Donation After Circulatory Determination of Death…

Abstract The need for organs suitable for transplantation has continued to rise as need outweighs availability. Increased demand has driven innovation in the field. Over the past ten years, donation..

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Aortic Balloon Occlusion in Circulatory Determination of Death Donors Undergoing Abdominal Normothermic Regional Perfusion?

Abstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...

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On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death

Abstract Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant..

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Direct procurement with machine perfusion and normothermic regional perfusion in donation after circulatory death heart transplantation

Abstract Background Donation after circulatory death (DCD) heart transplants have increased in the United States with direct procurement with machine perfusion (DPP) and thoracoabdominal normothermic regional perfusion (TA-NRP) techniques. There..

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The current landscape of in situ and ex situ machine perfusion utilization for liver grafts from cardiac donation after circulatory…

Abstract Donation after circulatory death (DCD) is driving the increase in deceased organ donors in the United States. Normothermic regional perfusion (NRP) and ex situ machine perfusion (es-MP) have been..

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Perfusión regional normotérmica (PRN) para la obtención de órganos.

Perfusión regional normotérmica (PRN) para la obtención de órganos en donación en asistolia controlada.   Ponente: Dr. Juan Blanco (España) Enfermero. Máster y Posgrado en Técnicas de perfusión y oxigenación..

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Brief hypothermic oxygenated perfusion provides cardioprotection in a pig model of donation after circulatory death

Abstract OBJECTIVES Donation after circulatory death provides excellent patient outcomes in heart transplantation; however, warm ischaemic graft damage remains a concern. We have reported that a brief period of hypothermic..

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Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry

Abstract BACKGROUND: A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated favorable outcomes in hearts recovered..

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Normothermic Regional Perfusion in Controlled Donation After the Circulatory Determination of Death: Understanding Where the Benefit Lies

Abstract Controlled donation after the circulatory determination of death (cDCDD) has emerged as a strategy to increase the availability of organs for clinical use. Traditionally, organs from cDCDD donors have..

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Extracorporeal lung perfusion and donation EVLPD in donation after circulatory death DCD

Extracorporeal lung perfusion and donation (EVLPD) in donation after circulatory death (DCD) patients is a groundbreaking advancement in organ transplantation, and Professor Sam Zeraatiannejaddavani, a world-renowned surgeon, has been at..

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Surgical Technique of Donation after Circulatory Death using Normothermic Regional Perfusion

Abstract Heart transplantation (HT) is the gold standard treatment of end-stage heart disease. Waitlist mortality remains high due to a shortage of available donor organs. Donation after circulatory death (DCD)..

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The potential benefits of monitoring oxygen delivery in relation to O2ERi and VCO2 during normothermic regional perfusion in DCD donors

As the field of organ transplantation continues to evolve, the use of Donation after Circulatory Death (DCD) donors has emerged as a critical method to expand the donor pool. However,..

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