Monthly Archives: junio 2026

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The hidden myocardium: Why intraoperative hypotension should be treated as myocardial injury prevention rather than a transient anaesthetic variable

Abstract Intraoperative hypotension (IOH) has traditionally been regarded as a transient and largely reversible physiological disturbance inherent to the administration of general and regional anaesthesia. However, contemporary perioperative outcomes research..

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Modeling the Cost-Effectiveness of Incorporating Extracorporeal Cardiopulmonary Resuscitation Strategy in Out-of-Hospital Cardiac Arrest Patients

Abstract Objectives: To evaluate the cost-effectiveness of implementing an extracorporeal cardiopulmonary resuscitation (ECPR) strategy for refractory out-of-hospital cardiac arrest (OHCA) compared with current practice in Singapore, where it is not..

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Clinical applications of oXiris membranes: Targeting inflammation and renal dysfunction in ICU patients

Abstract The oXiris membrane represents a notable advance in continuous renal replacement therapy for critically ill patients with severe infection, sepsis, and other conditions characterized by immune dysregulation. Built on..

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Management of Shock After Cardiac Surgery

Abstract Postoperative pathophysiology and impact from cardiopulmonary bypass The PCS population is unique due to patients’ exposure to cardiopulmonary bypass (CPB) and temporary cardiac arrest, which are associated with cytokine..

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Physiology, monitoring, and optimisation of perioperative tissue oxygenation: a narrative review

Abstract Maintenance of tissue oxygenation in patients having surgery is important as tissue hypoxia is a major determinant of organ failure. Tissue oxygenation follows a stepwise physiological pathway involving the..

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Case-specific optimal extracorporeal membrane oxygenation configuration for cardiogenic shock in the peripartum period: a case report

Abstract For pregnant patients with severe coronavirus disease 2019 (COVID-19) requiring veno-venous (V-V) extracorporeal membrane oxygenation (ECMO), the ideal timing of delivery is uncertain, particularly when complicated by cardiogenic shock...

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Precision neuroprotection in cardiac surgery: a structured narrative review of multimodal, data-driven perioperative care

Abstract Neurological injury remains a major contributor to morbidity, mortality, and long-term cognitive decline in patients undergoing cardiac surgery, despite significant advancements in surgical techniques and cardiopulmonary bypass (CPB) technology...

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Management of Extracorporeal Membrane Oxygenation for Cardiogenic Shock

Abstract Clinical Criteria and Assessment (Hypotension, Hypoperfusion, Rising Lactate, and Escalating Vasopressors) Profound hypotension, ongoing CS despite optimal medical treatment, escalating vasopressor requirements, rapidly deteriorating cardiac function, worsening lactic acidosis,..

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Efficacy, Safety, and Cost-Effectiveness of Cell Salvage in Cardiac Reoperations

Abstract Background: The aim of this study was to investigate the efficacy and safety of cell salvage (CS) use in cardiac reoperations and to conduct a cost analysis considering the Turkish..

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ROTEM versus conventional coagulation tests in evaluating coagulopathy and transfusion requirement in ECMO patients: A retrospective study

Abstract Introduction Critically ill ECMO patients face high bleeding risks from anticoagulation and other factors. Although viscoelastic tests, like ROTEM, are widely used to assess hemostasis, evidence for their superiority..

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Prevalence and outcomes of in-hospital cardiac arrest in the intensive care unit: a systematic review and meta-analysis

Abstract Background Cardiac arrest in the intensive care unit (ICU-CA) is distinct from other in-hospital cardiac arrests, involving critically ill patients in monitored settings. Its prevalence and outcomes remain unclear...

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A Trends Analysis and Scoping Review: Minimal Invasive Extracorporeal Circulation

Abstract Purpose The minimal invasive extracorporeal circulation (MiECC) was developed as abiocompatible alternative to conventional cardiopulmonary bypass (cCPB), intending to mitigate haemodilution, lessen the systemic inflammatory response, and enhance organ..

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Early Initiation of Continuous Renal Replacement Therapy in Neonatal Extracorporeal Life Support: A 17-Year Retrospective Review

Abstract Neonatal fluid management in extracorporeal life support (ECLS) is complex, with the goal of improving outcomes while preventing complications. This study evaluates the impact of early continuous renal replacement..

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Preoperative Transcranial Doppler Findings and Postoperative Delirium After Cardiac Surgery in Elderly Patients: A Prospective Observational Study

Abstract Postoperative delirium (POD) is a common neurocognitive complication after cardiac surgery in elderly patients and is associated with adverse clinical outcomes. Impaired cerebral autoregulation and reduced cerebrovascular reserve may..

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Venopulmonary Extracorporeal Membrane Oxygenation: Overview, Applications, and Current Evidence

Abstract Extracorporeal membrane oxygenation (ECMO) has become an essential supportive therapy for patients with severe respiratory and/or cardiac failure. While conventional configurations such as veno-venous and veno-arterial ECMO have well-established..

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Expanding the Boundaries of Minimally Invasive Cardiac Surgery: Initial Experience with Multivalve Procedures

Abstract Background/Objectives: Minimally invasive valve surgery via right minithoracotomy is well established for isolated aortic and mitral procedures, but its application to multivalve operations remains uncommon and clinical data are..

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A Novel Neonatal Brain Injury Score for Infants With Congenital Diaphragmatic Hernia

Abstract Background Infants with congenital diaphragmatic hernia (CDH) are at increased risk of neuroimaging abnormalities and neurodevelopmental impairment. There is no standardized neuroimaging scoring system in this patient population. Our..

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Association between lactate to albumin ratio and 28-day all-cause mortality in patients with extracorporeal membrane oxygenation: a retrospective multi-cohort study

Abstract Background The relationship between lactate-to-albumin ratio (LAR) and mortality in patients with cardiogenic etiology undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) remains unclear. Against this backdrop, the present study is..

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Does Inflammatory Prognostic Index Predict Postoperative Outcomes in Coronary Artery Bypass Grafting?

Abstract Background: The inflammatory prognostic index (IPI) is a novel hematological parameter that reflects both inflammatory burden and immune status. Despite several studies on this new index, the prognostic value..

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Acute brain injury in adult post-cardiotomy cardiogenic shock patients receiving central vs. peripheral VA-ECMO: A single-center experience and systematic review…

Abstract Background Postcardiotomy cardiogenic shock (PCS) is a life-threatening complication after adult cardiac surgery that frequently necessitates venoarterial extracorporeal membrane oxygenation (VA-ECMO). Central and peripheral VA-ECMO cannulation strategies generate distinct..

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Left Ventricular Venting Strategies for Cardiogenic Shock in Patients Treated With Extracorporeal Cardiopulmonary Support V-A ECMO: From Left Ventricular Unloading…

Abstract While veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become central in the management of patients in advanced stages of cardiogenic shock due to its relative ease of deployment, there..

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The Utility of Extracorporeal Membrane Oxygenation in the Setting of Chronic Thromboembolic Pulmonary Hypertension

Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive disease that occurs due to fibrotic remodeling of the pulmonary vessels. This leads to increased pressure overload onto the right ventricle,..

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Cardiopulmonary Bypass Circuit Tubing Rupture During Unplanned Conversion From Off-Pump Coronary Artery Bypass Graft Procedure: A Case Report

Abstract Cardiopulmonary bypass (CPB) is an essential component of many cardiac surgical procedures, but carries inherent risks related to its reliance on extracorporeal circulation and mechanical circuitry. Mechanical complications, though..

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Perioperative Anemia and Patient Blood Management in Cardiac Surgery: A Scientific Statement From the American Heart Association

Abstract Perioperative anemia and red blood cell transfusions are important risk factors for morbidity and mortality in cardiac surgery. Preoperative anemia is common, with up to 50% of patients presenting..

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Innovative use of quality indicators during cardiopulmonary bypass: a goal directed perfusion strategy using real-time area under the threshold analysis

Abstract This study aims to assess current quality indicators and determine the added value of total area under the threshold (TAUT) and largest area under the threshold (LAUT) for risk..

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Optimizing Regional Access to Extracorporeal Cardiopulmonary Resuscitation: A Geographic-Information-System-Based Comparison of Hospital- and Prehospital-Initiated Strategies in Nara Prefecture, Japan

Abstract Background: Extracorporeal cardiopulmonary resuscitation (ECPR) can improve outcomes following refractory out-of-hospital cardiac arrest (OHCA); however, access is constrained by geography and resources. This study compared two strategies against the..

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Safety of prolonged anticoagulation-free venovenous ECMO management beyond 72 hours in post-traumatic ARDS: A single-center retrospective cohort study

Abstract Introduction Standard anticoagulation protocols for patients with trauma-related acute respiratory distress syndrome (TR-ARDS) undergoing venovenous extracorporeal membrane oxygenation (VV-ECMO) are often inapplicable due to high bleeding risks. This study..

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Factors associated with acute intestinal ischemia after cardiac surgery: A propensity score-matched study

Abstract Objectives Acute intestinal ischemia from cardiac surgery is rare but highly lethal. Conventional risk models lack preoperative markers reflecting splanchnic arterial capacity. We hypothesized that subclinical abdominal atherosclerosis predisposes..

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Multidisciplinary blood conservation practices for transfusion-free congenital heart surgery

Abstract Team Sport The most effective method for achieving sustainable blood-sparing practices is a pragmatic and individualized approach within a multidisciplinary framework. For every case, direct, clear, and intentional communication..

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Reconsidering boundaries: extracorporeal membrane oxygenation candidacy for neonates with congenital anomalies of the kidney and urinary tract

Abstract The role of extracorporeal membrane oxygenation (ECMO) in neonates with congenital anomalies of the kidney and urinary tract (CAKUT) remains one of the more contested frontiers at the intersection..

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