Monthly Archives: agosto 2026

thumbnail
0 comment

Standardized femoral artery cannulation and ischemia-prevention protocol for minimally invasive cardiac surgery

Abstract Objectives In minimally invasive cardiac surgery, femoral artery cannulation is widely used; however, it may cause lower-limb ischemia. We developed a standardized patient-selection strategy, a femoral artery–cannulation technique, and..

Read More
thumbnail
0 comment

Extracorporeal Membrane Oxygenation Combined With Embolectomy May Yield Better Outcomes Than Extracorporeal Membrane Oxygenation Alone or With Thrombolysis for Acute…

Abstract Veno-arterial extracorporeal membrane oxygenation (ECMO) is used to support patients with high-risk pulmonary embolism (HR-PE) with cardiogenic shock, but data on mid- and long-term outcomes after reperfusion remain limited...

Read More
thumbnail
0 comment

The immunomodulatory effect of continuous ultrafiltration during pediatric cardiac surgery

Abstract Background Cardiopulmonary bypass is associated with systemic inflammation during pediatric cardiac surgery and features elevated systemic concentrations of complement, cytokines and chemokines. The objective of this study is to..

Read More
thumbnail
0 comment

Pediatric Respiratory Failure and Support With Prolonged Extracorporeal Membrane Oxygenation: Multicenter Cohort Using the Extracorporeal Life Support Organization Registry, 1989–2021

Abstract Objectives: To characterize outcomes in children supported with 14 days or more of extracorporeal membrane oxygenation (ECMO) for respiratory indications. Design: Retrospective analysis of the Extracorporeal Life Support Organization..

Read More
thumbnail
0 comment

Redo cardiac and great vessel surgery: necessity of meticulous preparation and contingency planning

Abstract Recent advances in surgical techniques and perioperative management have significantly improved the outcomes of cardiac and/or thoracic aortic surgery compared with earlier decades. However, redo procedures remain particularly challenging,..

Read More
thumbnail
0 comment

ECPR Prague - 29/31 Oct

This year we are bringing NextGen to ECPR Prague School 2026, 29–31 October, for three days dedicated to ECPR — from the first critical decisions to survivorship and the future..

Read More
thumbnail
0 comment

Membrane lung dead space and membrane lung impairment: An exploratory retrospective study in COVID-19 patients

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) is a key therapy for refractory respiratory failure, but can trigger systemic inflammation and prothrombotic activation that impair the membrane lung (ML)...

Read More
thumbnail
0 comment

Modified cardiopulmonary bypass strategy for severe glucose-6-phosphate dehydrogenase deficiency during coronary artery bypass grafting: A practical perfusion technique

Abstract Background Severe glucose-6-phosphate dehydrogenase (G6PD) deficiency presents unique challenges during cardiopulmonary bypass (CPB) because of increased susceptibility to oxidative injury and haemolysis. Published guidance regarding optimal perfusion management remains..

Read More
thumbnail
0 comment

The Minnesota Mobile Resuscitation Consortium ECMO truck: a feasibility study for ECPR in refractory out-of-hospital cardiac arrest

Abstract Background Refractory ventricular fibrillation/ventricular tachycardia (VF/VT) out-of-hospital cardiac arrest (OHCA) carries poor survival with conventional resuscitation. Extracorporeal cardiopulmonary resuscitation (ECPR) improves outcomes in selected patients; however, time to reperfusion..

Read More
thumbnail
0 comment

Differential Regulation of Neutrophil Elastase Release vs. NET Generation After Cardiopulmonary Bypass

Abstract Cardiopulmonary bypass (CPB) during heart surgery provokes an inflammatory response that can cause post-operative organ injury, yet how CPB shapes key neutrophil effector programs is unclear. We investigated whether..

Read More
thumbnail
0 comment

Carboxyhemoglobin as a biomarker of hemolysis: A systematic review and meta-analysis

Abstract Background: Hemolysis occurs frequently in patients requiring mechanical circulatory support (MCS) and is associated with worse outcomes. Carboxyhemoglobin (CO-Hb) has been suggested as a potential biomarker for detection of..

Read More
thumbnail
0 comment

ECPR readiness without perfusionist support: a cross-sectional national survey on circuit preparation, team structure, and training

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is a time-critical intervention for selected patients with refractory cardiac arrest. Survival depends on minimizing low-flow duration before ECPR initiation. Timely deployment requires organizational..

Read More
thumbnail
0 comment

Impact of postcardiotomy ECMO utilization after the Norwood procedure in the United States

Abstract Background Norwood surgery is the first stage in the surgical palliation of hypoplastic left heart syndrome (HLHS) and its variants. Postcardiotomy extracorporeal membrane oxygenation (ECMO) may be required in..

Read More
thumbnail
0 comment

Sevoflurane Consumption During Cardiac Surgery With Extracorporeal Circulation: The Effect of Carbon Dioxide Field Flooding

Abstract Objectives To determine whether carbon dioxide (CO2) field flooding during extracorporeal circulation (ECC) is associated with increased hourly sevoflurane consumption. Secondary objectives evaluated consumption differences between nonflooded procedures and..

Read More
thumbnail
0 comment

Structural Covariance Analysis of Altered Brain Development in Neonates With Congenital Heart Disease After Surgery

Abstract Background Brain development is altered in neonates with congenital heart disease (CHD), with well-characterised reductions in regional brain volumes and enlargement of CSF spaces. However, perioperative morphological changes remain..

Read More
thumbnail
0 comment

Assessing accessibility to the extracorporeal cardiopulmonary resuscitation pathway for out-of-hospital cardiac arrests in London

Abstract Aims Extracorporeal cardiopulmonary resuscitation (ECPR) may improve outcomes in selected patients with refractory out-of-hospital cardiac arrest (OHCA), but timely access is essential. In Greater London, a prehospital ECPR pathway..

Read More
thumbnail
0 comment

Pregnancy-associated extracorporeal life support: insights from a nationwide dual-cohort analysis

Abstract Background Extracorporeal life support (ECLS) is used as rescue therapy for refractory cardiopulmonary failure. Population-level evidence on prognosis and long-term sequelae in patients requiring ECLS during pregnancy or the..

Read More
thumbnail
0 comment

Not Just for the Dying: The Benefits of Routine Palliative Medicine Consultation in ECMO Care

Abstract Introduction Palliative medicine (PM) aims to enhance the quality of life of patients and families facing serious illness. Currently, there are no national guidelines for involving PM in the..

Read More
thumbnail
0 comment

Cerebral protection strategies in aortic arch surgery: a review of techniques and outcomes

Abstract Background: Cerebral protection is a key determinant of perioperative outcomes in aortic arch surgery. Despite significant advances, optimal strategies regarding temperature, perfusion modality, and cannulation site remain controversial, with..

Read More
thumbnail
0 comment

A regional partnership model for VA-ECMO initiation and transfer from remote centers using air medical transport

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has become an accepted treatment modality for refractory cardiogenic shock (CS). However, its use is limited to tertiary centers due to resource allocation, education,..

Read More
thumbnail
0 comment

2026 American Association for Thoracic Surgery (AATS) expert consensus statement: Antithrombotic management of neonates/infants undergoing cardiac interventions

Abstract Objectives The hemostatic system in neonates and infants with congenital heart disease is distinct as a result of developmental and disease-specific factors, necessitating population-specific periprocedural evaluation and antithrombotic management...

Read More
thumbnail
0 comment

Decreasing the post surgical ooze: Utilizing a perioperative guideline to decrease transfusion needs following congenital diaphragmatic hernia repair on ECMO

Abstract Purpose To evaluate changes in post-operative transfusion requirements of infants undergoing congenital diaphragmatic hernia (CDH) repair on ECMO following implementation of a perioperative guideline. Methods In 2021, a multidisciplinary..

Read More
thumbnail
0 comment

Impella Versus VA-ECMO in Cardiogenic Shock: An Updated Systematic Review and Meta-Analysis With Exploratory Matched-Cohort Analyses

Abstract Observational studies comparing Impella and venoarterial extracorporeal membrane oxygenation (VA-ECMO) in cardiogenic shock have reported inconsistent findings. We performed an updated systematic review and meta-analysis, with exploratory matched-cohort analyses..

Read More
thumbnail
0 comment

Intravenous iron to treat anaemia before cardiac surgery (ITACS): international, double blind, placebo controlled randomised trial

Abstract Objective To evaluate the effects of intravenous iron on red cell transfusion and recovery after cardiac surgery. Design International, multicentre, double blind, placebo controlled randomised trial (ITACS). Setting 33..

Read More
thumbnail
0 comment

Physiological anticoagulant deficiencies: pathogenesis, diagnosis, and clinical implications

Abstract Physiological anticoagulants are essential regulators of coagulation, and their deficiency shifts hemostasis toward a prothrombotic state, increasing the risk of venous thromboembolism. The main physiological anticoagulants, antithrombin (AT), protein..

Read More
thumbnail
0 comment

The Trial of Heart Transplant vs LVAD: Could it Be Done? Would the Answer Matter?

Abstract Introduction to the Problem Triage of patients referred with advanced heart failure (HF) continues to revive the classic question: can we conduct a randomized trial comparing heart transplantation with..

Read More
thumbnail
0 comment

Venoarterial ECMO management: Clinical considerations

Abstract Venoarterial extracorporeal membrane oxygenation (V-A ECMO) is a technique used to provide short-term circulatory and respiratory support in patients with refractory cardiogenic shock and cardiac arrest who do not..

Read More
thumbnail
0 comment

Elevated Cardiopulmonary Bypass Flow for Renal Protection in Cardiac Surgery: A Randomized Trial

Abstract BACKGROUND: Acute kidney injury (AKI) is a common and severe complication after cardiac surgery with cardiopulmonary bypass (CPB). Experimental data suggest that increasing CPB flow beyond standard targets may..

Read More
thumbnail
0 comment

Extracorporeal Carbon Dioxide Removal Combined With Inhaled Nitric Oxide for Hypercapnic Acute Respiratory Distress Syndrome With Active Airway Hemorrhage: A…

Abstract Low-flow extracorporeal carbon dioxide removal (ECCO2R) may be useful when severe hypercapnia limits ultra-protective ventilation but full venovenous extracorporeal membrane oxygenation (VV-ECMO) is not pursued. We describe a 68..

Read More
thumbnail
0 comment

Antimicrobial use in adult patients receiving extracorporeal membrane oxygenation in a center without routine prophylaxis

Abstract Antimicrobial use in patients receiving extracorporeal membrane oxygenation (ECMO) is poorly described. In this study, evaluating antimicrobial use at a single center without ECMO-specific antimicrobial prophylaxis protocols, antimicrobials were..

Read More