Liquid Lung Rest During Extracorporeal Life Support in a Neonatal Porcine Model of Acute Lung Injury
Abstract In patients with severe lung injury, extracorporeal life support (ECLS) enables lung rest, but the optimal strategy is unknown. This study compared liquid lung rest (LLR) versus standard gas rest ventilation..
Read MoreAbstract Background: Among infants undergoing cardiac surgery, AKI may affect as many as 40% of this population and carries an unfavorable prognosis. A range of contributors has been implicated, including early..
Read MoreAbstract Fluid administration and fluid balance are both important clinical considerations in the management of patients receiving extracorporeal membrane oxygenation (ECMO). Insufficient intravascular volume may limit the output of preload-dependent..
Read MoreAbstract Background and Objectives: Endoscopic beating-heart tricuspid valve (TV) surgery is increasingly adopted in cardiac surgery due to its association with improved postoperative recovery. Conventional approaches require jugular vein cannulation..
Read MoreAbstract Introduction In patients with prior valve replacement requiring venoarterial extracorporeal membrane oxygenation (VA ECMO), there is a risk of prosthetic valve thrombosis (PVT) due to intracardiac stasis. We describe..
Read MoreAbstract Patients supported with peripheral femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently face the challenge of determining the optimal timing for weaning trials, as no universally standardized bedside method is..
Read MoreAbstract Early rehabilitation during venovenous extracorporeal membrane oxygenation used as a bridge to recovery (VV ECMO–BTR) may help preserve functional capacity. We retrospectively analyzed 153 adults supported with VV ECMO–BTR..
Read MoreAbstract Importance Two percent to 50% of patients undergoing elective cardiac surgery experience acute kidney injury (AKI) postoperatively. Medications to prevent AKI after elective cardiac surgery have not been identified. Objective In..
Read MoreAbstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) is an advanced therapy for patients with respiratory failure refractory to conventional management. Volume overload and elevated lactate levels have been associated..
Read MoreAbstract Objective Cardiac surgery-associated acute kidney injury is a common and serious complication of cardiac surgery. Albumin solution is a commonly administered fluid in cardiac surgery patients; the role of..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) during cardiopulmonary resuscitation (ECPR) is a lifesaving technology that has been widely described for in-hospital cardiac arrest in children with underlying cardiac disease. However, data..
Read MoreAbstract Background: Conflicting data exist regarding the survival benefit of mechanical left ventricular (LV) unloading in patients receiving peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shock (CS). In..
Read MoreAbstract BACKGROUND: Approximately 10% to 15% of all red blood cell (RBC) transfusions in the United States and United Kingdom occur during cardiac surgery. Despite efforts to standardize patient blood..
Read MoreAbstract With the rapid development of life support technologies in the biomedical field, artificial hibernation has shown significant potential in the area of neural tissues and organ protection. This paper..
Read MoreAbstract Rationale: Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) requiring invasive mechanical ventilation (IMV) are associated with high mortality and long-term disability. Extracorporeal CO₂ removal (ECCO₂R) using modern high-capacity..
Read MoreImpact of intra-aortic balloon pump support on cerebral blood flow velocity during venoarterial ECMO
Abstract Introduction Venoarterial extracorporeal membrane oxygenation (V-A ECMO) is frequently combined with intra-aortic balloon pump (IABP) support in patients with refractory cardiogenic shock. Although IABP may reduce V-A ECMO–related afterload,..
Read MoreAbstract Background/Objectives: Evidence on outcomes after repeat VA-ECMO in adults remains limited. This study aimed to compare survival and post-discharge functional outcomes between adults requiring a second VA-ECMO run and..
Read MoreAbstract Background Thoracoabdominal aortic replacement requires one-lung ventilation (OLV) and partial cardiopulmonary bypass (CPB). During right-sided OLV with femoral partial CPB, the coronary and supra-aortic branches are perfused by native..
Read MoreAbstract Objectives Cardiopulmonary bypass (CPB) priming may influence haemodilution, bleeding, and end-organ injury during HeartMate 3 (HM3) implantation, but evidence in contemporary left ventricular assist device (LVAD) surgery is limited...
Read MoreAbstract One theme worth emphasizing is that “ECMO prediction” is not a single task. Some models are intended to inform decisions before cannulation, whereas others incorporate variables such as ECMO..
Read MoreAbstract Objectives:Hypothermic oxygenated perfusion reduces ischemia-reperfusion injury and improves early graft function in extended criteria donor liver transplant. However, use of machine perfusion may be limited because of lack of..
Read MoreAbstract Liver transplantation (LT) is an established therapy for patients with end-stage liver disease. Advances in surgical technique, anesthetic management, and standardization of perioperative care have significantly improved outcomes, making..
Read MoreAbstract Background: Hemoperfusion has emerged as a potential extracorporeal blood purification strategy for attenuating inflammation during cardiopulmonary bypass (CPB), but perioperative biomarker trajectory data remain limited. This pilot comparative study..
Read MoreAbstract Background and Objectives: Prolonged intensive care unit (ICU) stay following coronary artery bypass grafting (CABG) remains a major clinical challenge. The aim of this study was to identify preoperative..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is a vital therapy for patients with severe cardiac and pulmonary failure. Despite technological advances, oxygenator dysfunction remains common, yet comparative clinical data across devices..
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving therapeutic modality in children. Outcome is multifactorial with debates regarding predictors of weaning success and mortality. Objective To explore predictors of..
Read MoreAbstract BACKGROUND We sought to determine if modified ultrafiltration (MUF) in the current era was associated with improved outcomes after neonatal cardiopulmonary bypass (CPB). METHODS Retrospective analysis of the PC4/NEPHRON..
Read MoreAbstract Background: Numerous studies have demonstrated that both cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) are often associated with adverse outcomes or immune dysregulation when platelet counts decline during..
Read MoreAbstract Oxygenator thrombosis is a major complication during extracorporeal membrane oxygenation (ECMO), but systemic anticoagulation may be contraindicated by active hemorrhage, recent surgery, intracranial injury, or severe coagulopathy. Circuit-directed nitric..
Read MoreAbstract Background Levosimendan is often given during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support with the intention of facilitating weaning. The available evidence, however, has been derived largely from nonrandomized studies..
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