Abstract Background/Objectives: Preoperative anemia and iron deficiency increase transfusion risk in cardiac surgery. We evaluated outcomes associated with a Patient Blood Management (PBM) pathway and assessed the robustness of these..
Read MoreAbstract Background Systemic inflammatory response syndrome (SIRS) is a significant postoperative complication in older patients leading to higher morbidity and mortality rates. This study investigates the predictive value of preoperative..
Read MoreAbstract Background Intraoperative cell salvage is widely used in pediatric scoliosis surgery to reduce allogeneic transfusion requirements. However, its clinical effectiveness and economic impact remain uncertain. The objective of this..
Read MoreAbstract Purpose Out-of-bed (OOB) mobility is often expected of patients bridged to lung transplantation (LTx) on venovenous (VV) extracorporeal membrane oxygenation (ECMO), but the course of listed patients who never..
Read MoreAbstract Background Non-technical skills (NTS) such as teamwork, communication and leadership are essential for surgical safety, but their impact on patient outcomes is uncertain. This systematic review evaluated whether NTS..
Read MoreAbstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..
Read MoreAbstract Background & Aims Postoperative renal failure remains a major determinant of morbidity and mortality after cardiac surgery, with limited preventive pharmacological options. Enoximone, a phosphodiesterase III inhibitor with inotropic..
Read MoreAbstract Background Post-decannulation management of residual extracorporeal membrane oxygenation (ECMO) circuit blood is an under-standardized issue in critical care and perioperative patient blood management. Whether residual circuit blood should be..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is associated with a high risk of neurologic injury in pediatric patients, and early detection of injury is often challenging because the clinical examination is..
Read MoreAbstract Introduction Myocardial injury is a significant contributor to 30-day mortality after cardiac surgery with cardiopulmonary bypass. We aimed to investigate the association between mean arterial pressure, norepinephrine use during..
Read MoreAbstract Objectives Long-term outcomes of emergent extracorporeal membrane oxygenation (ECMO) initiated outside the operating room remain poorly defined. We evaluated long-term outcomes after emergent ECMO support outside the operating room..
Read MoreAbstract I read with interest the systematic review and meta-analysis by Samaniego-Laguna et al., which addresses whether intraoperative hemoadsorption during cardiopulmonary bypass (CPB) reduces postoperative complications. The reported reduction in..
Read MoreAbstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..
Read MoreAbstract Background/Objectives: Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), increasing morbidity and prolonging hospitalization. This study aimed to develop and validate an..
Read MoreAbstract Thoracoabdominal normothermic regional perfusion (TA-NRP) is increasingly adopted for cardiac allograft procurement in controlled donation after circulatory death (cDCD). In settings where ante-mortem femoral guidewire placement is permitted, peripheral..
Read MoreAbstract In a recent edition of Anesthesiology, Wijk et al. examine the differential effect on the kidney of cardiopulmonary bypass (CPB) with flow rates of 2.4 L/min/m2 and 2.9 L/min/m2...
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) provides heart/lung support for critically ill patients. While advances in research have improved the overall design and performance of ECMO circuits, complications such as hemolysis..
Read MoreAbstract We read with interest the editorial by Bolliger et al. on heparin resistance. We report a bedside dilemma in a child who experienced cardiopulmonary arrest from septic pulmonary embolism..
Read MoreAbstract Background/Objectives: Cardiopulmonary bypass (CPB) induces a systemic inflammatory response that may contribute to postoperative organ dysfunction. However, the effects of pulsatile and non-pulsatile CPB on the inflammatory response remain..
Read MoreAbstract Purpose Ultrafiltration (UF) reduces dilution of all blood components during cardiopulmonary bypass (CPB), but its impact on coagulation performance remains unclear. We examined whether conventional UF mitigates the CPB-induced..
Read MoreAbstract Introduction Extracorporeal membrane oxygenation (ECMO) provides life-sustaining gas exchange and haemodynamic support for critically ill patients with severe respiratory or circulatory failure. Paediatric patients supported on ECMO often represent..
Read MoreAbstract Background and Objectives: Myocardial protection during on-pump coronary artery bypass grafting (CABG) limits ischaemic injury, particularly in patients with left main coronary artery disease (LMCAD), in whom severe proximal..
Read MoreAbstract Failure of extracorporeal membrane oxygenation (ECMO) circuit components can precipitate abrupt hemodynamic or respiratory collapse; however, the evidence linking specific component malfunctions to patient harm remains sparse, and device-specific..
Read MoreAbstract Background: Extracorporeal membrane oxygenation (ECMO) provides life support to patients undergoing cardiopulmonary surgeries when other interventions are ineffective. Unfractionated heparin (UFH) is routinely used during ECMO due to the..
Read MoreAbstract Background Operating a cardiopulmonary bypass (CPB) system requires high-level multitasking while simultaneously maintaining continuous situation awareness. Among these, venous reservoir level is particularly critical. This level is monitored using..
Read MoreAbstract Precise control of dissolved oxygen is essential for reproducing physiologically relevant conditions in microfluidic cell culture systems. Here, we present a standalone, polydimethylsiloxane-free gas exchange unit (GEU) which enables..
Read MoreAbstract Venovenous extracorporeal membrane oxygenation (VV ECMO) candidacy decision-making processes vary within and between centers. An underexplored potential contributor to this variability is the care model. Fundamental differences in infrastructure,..
Read MoreAbstract Measles is resurgent worldwide, and although vaccine-preventable, severe disease can progress to cardiorespiratory failure refractory to conventional support. This study aimed to determine whether extracorporeal membrane oxygenation (ECMO) is..
Read MoreAbstract Objectives To identify if the delivery of oxygen over consumption of oxygen (DO2/VO2) ratio is significantly associated with clinical outcomes such as mortality, need for heart transplantation, or need..
Read MoreAbstract Background. Cerebral autoregulation (CA) is estimated by assessing the association between variations of mean cerebral blood velocity (MCBv) and mean arterial pressure (MAP). Recently, regional oxygen saturation (rSO2) has..
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