Monthly Archives: noviembre 2026

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Clinical and Economic Outcomes Associated with Structured Preoperative Anemia Management in Elective Cardiac Surgery: A Patient Blood Management Cohort Study

Abstract Background/Objectives: Preoperative anemia and iron deficiency increase transfusion risk in cardiac surgery. We evaluated outcomes associated with a Patient Blood Management (PBM) pathway and assessed the robustness of these..

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Preoperative inflammatory indicators predict postoperative SIRS after cardiac surgery with cardiopulmonary bypass in older patients

Abstract Background Systemic inflammatory response syndrome (SIRS) is a significant postoperative complication in older patients leading to higher morbidity and mortality rates. This study investigates the predictive value of preoperative..

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Clinical Effectiveness and Economic Impact of Intraoperative Cell Salvage in Pediatric Scoliosis Surgery

Abstract Background Intraoperative cell salvage is widely used in pediatric scoliosis surgery to reduce allogeneic transfusion requirements. However, its clinical effectiveness and economic impact remain uncertain. The objective of this..

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Out-of-bed mobility during venovenous ECMO among patients listed for lung transplantation: A descriptive single-center cohort study

Abstract Purpose Out-of-bed (OOB) mobility is often expected of patients bridged to lung transplantation (LTx) on venovenous (VV) extracorporeal membrane oxygenation (ECMO), but the course of listed patients who never..

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Impact of non-technical skills training on patient outcomes in surgery: a systematic review and meta-analysis

Abstract Background Non-technical skills (NTS) such as teamwork, communication and leadership are essential for surgical safety, but their impact on patient outcomes is uncertain. This systematic review evaluated whether NTS..

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Systemic Inflammatory Response During Coronary Artery Bypass Grafting with Cardiopulmonary Bypass: Cellular and Molecular Mechanisms

Abstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..

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Administration of Enoximone for the Optimisation of Renal Function in Cardiac Surgery: Final Results of a Multicentre Study

Abstract Background & Aims Postoperative renal failure remains a major determinant of morbidity and mortality after cardiac surgery, with limited preventive pharmacological options. Enoximone, a phosphodiesterase III inhibitor with inotropic..

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Post-decannulation management of residual ECMO circuit blood: a national cross-sectional survey in China

Abstract Background Post-decannulation management of residual extracorporeal membrane oxygenation (ECMO) circuit blood is an under-standardized issue in critical care and perioperative patient blood management. Whether residual circuit blood should be..

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Quantitative Electroencephalography Correlates With Acute Neurologic Events in Extracorporeal Membrane Oxygenation: A Pediatric Case Series

Abstract Extracorporeal membrane oxygenation (ECMO) is associated with a high risk of neurologic injury in pediatric patients, and early detection of injury is often challenging because the clinical examination is..

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Risk Factors for Myocardial Injury During Cardio-Pulmonary Bypass-Assisted Heart Surgery: A Retrospective Single-Center Study

Abstract Introduction Myocardial injury is a significant contributor to 30-day mortality after cardiac surgery with cardiopulmonary bypass. We aimed to investigate the association between mean arterial pressure, norepinephrine use during..

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Extracorporeal Membrane Oxygenation Outside the Operating Room in Neonates and Infants

Abstract Objectives Long-term outcomes of emergent extracorporeal membrane oxygenation (ECMO) initiated outside the operating room remain poorly defined. We evaluated long-term outcomes after emergent ECMO support outside the operating room..

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Interpreting the Acute Kidney Injury Signal With Intraoperative Hemoadsorption During Cardiopulmonary Bypass: Methodological Considerations

Abstract I read with interest the systematic review and meta-analysis by Samaniego-Laguna et al., which addresses whether intraoperative hemoadsorption during cardiopulmonary bypass (CPB) reduces postoperative complications. The reported reduction in..

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Early Metabolomic Changes During Extracorporeal Membrane Oxygenation Are Associated with Subsequent Acute Brain Injury

Abstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..

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Exploratory Modeling of Postoperative Atrial Fibrillation After Cardiac Surgery with Cardiopulmonary Bypass Using Inflammatory Biomarkers and Clinical-Surgical Factors

Abstract Background/Objectives: Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB), increasing morbidity and prolonging hospitalization. This study aimed to develop and validate an..

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Differential Oxygenation During Peripheral Thoracoabdominal Normothermic Regional Perfusion in Controlled Donation After Circulatory Death: An Underrecognized Cause of Potential Allograft…

Abstract Thoracoabdominal normothermic regional perfusion (TA-NRP) is increasingly adopted for cardiac allograft procurement in controlled donation after circulatory death (cDCD). In settings where ante-mortem femoral guidewire placement is permitted, peripheral..

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Kidney Function Following Cardiopulmonary Bypass: The Harbinger of a Poor Outcome?

Abstract In a recent edition of Anesthesiology, Wijk et al. examine the differential effect on the kidney of cardiopulmonary bypass (CPB) with flow rates of 2.4 L/min/m2 and 2.9 L/min/m2...

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Challenges and opportunities in ECMO monitoring: A mixed-methods appraisal

Abstract Extracorporeal membrane oxygenation (ECMO) provides heart/lung support for critically ill patients. While advances in research have improved the overall design and performance of ECMO circuits, complications such as hemolysis..

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Pseudo-Heparin Resistance in a Child on Extracorporeal Membrane Oxygenation

Abstract We read with interest the editorial by Bolliger et al. on heparin resistance. We report a bedside dilemma in a child who experienced cardiopulmonary arrest from septic pulmonary embolism..

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Effects of Pulsatile and Non-Pulsatile Cardiopulmonary Bypass on Early Inflammatory Response After Cardiac Surgery: A Secondary Biomarker Analysis of a…

Abstract Background/Objectives: Cardiopulmonary bypass (CPB) induces a systemic inflammatory response that may contribute to postoperative organ dysfunction. However, the effects of pulsatile and non-pulsatile CPB on the inflammatory response remain..

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Conventional ultrafiltration increases viscoelastic clot firmness during cardiopulmonary bypass: a prospective observational study

Abstract Purpose Ultrafiltration (UF) reduces dilution of all blood components during cardiopulmonary bypass (CPB), but its impact on coagulation performance remains unclear. We examined whether conventional UF mitigates the CPB-induced..

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Nutrition therapy in Paediatric patients requiring ExtraCorporeal Membrane Oxygenation: Protocol for a prospective observational multisite study (PAENUT ECMO)

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) provides life-sustaining gas exchange and haemodynamic support for critically ill patients with severe respiratory or circulatory failure. Paediatric patients supported on ECMO often represent..

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Combined Antegrade–Retrograde Cardioplegia for Myocardial Protection During Coronary Artery Bypass Grafting in Patients with Left Main Coronary Artery Disease: The…

Abstract Background and Objectives: Myocardial protection during on-pump coronary artery bypass grafting (CABG) limits ischaemic injury, particularly in patients with left main coronary artery disease (LMCAD), in whom severe proximal..

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Postmarket Surveillance of ECMO Pump and Control Console Malfunctions: Insights from the MAUDE Database

Abstract Failure of extracorporeal membrane oxygenation (ECMO) circuit components can precipitate abrupt hemodynamic or respiratory collapse; however, the evidence linking specific component malfunctions to patient harm remains sparse, and device-specific..

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Real-world outcomes of unfractionated heparin plus antithrombin concentrate versus bivalirudin in adult patients undergoing extracorporeal membrane oxygenation

Abstract Background: Extracorporeal membrane oxygenation (ECMO) provides life support to patients undergoing cardiopulmonary surgeries when other interventions are ineffective. Unfractionated heparin (UFH) is routinely used during ECMO due to the..

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Predictive monitoring of venous reservoir level fluctuations and rapid depletion during CPB via real-time image analysis

Abstract Background Operating a cardiopulmonary bypass (CPB) system requires high-level multitasking while simultaneously maintaining continuous situation awareness. Among these, venous reservoir level is particularly critical. This level is monitored using..

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Development of a Flat-Sheet Membrane Gas Exchange Unit for Oxygen Control in Microfluidic Systems

Abstract Precise control of dissolved oxygen is essential for reproducing physiologically relevant conditions in microfluidic cell culture systems. Here, we present a standalone, polydimethylsiloxane-free gas exchange unit (GEU) which enables..

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Medical Versus Surgical Respiratory Extracorporeal Membrane Oxygenation Candidacy Processes Are Similar

Abstract Venovenous extracorporeal membrane oxygenation (VV ECMO) candidacy decision-making processes vary within and between centers. An underexplored potential contributor to this variability is the care model. Fundamental differences in infrastructure,..

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Extracorporeal membrane oxygenation for life-threatening measles in children: a case series

Abstract Measles is resurgent worldwide, and although vaccine-preventable, severe disease can progress to cardiorespiratory failure refractory to conventional support. This study aimed to determine whether extracorporeal membrane oxygenation (ECMO) is..

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The Association of the Systemic Oxygen Delivery to Oxygen Consumption Ratio With Mortality, Heart Transplantation, and Mechanical Circulatory Support

Abstract Objectives To identify if the delivery of oxygen over consumption of oxygen (DO2/VO2) ratio is significantly associated with clinical outcomes such as mortality, need for heart transplantation, or need..

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Assessing cerebral autoregulation impairment via short-time correlation-based markers derived from transcranial Doppler and near-infrared spectroscopy signals during general anesthesia in…

Abstract Background. Cerebral autoregulation (CA) is estimated by assessing the association between variations of mean cerebral blood velocity (MCBv) and mean arterial pressure (MAP). Recently, regional oxygen saturation (rSO2) has..

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