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Percutaneous Versus Surgical Cannulation for Femoro-Femoral Venoarterial Extracorporeal Membrane Oxygenation: A Retrospective Cohort Study on Cannulation-Related Complications

Abstract Background Cannulation for peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) can lead to severe local complications. This study evaluated site-specific complications between percutaneous and surgical cannulation techniques for femoro-femoral..

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Predictive and prognostic factors for prolonged ECMO: a multicenter retrospective study

Abstract Purpose Prolonged ECMO has become more common during the COVID-19 pandemic but is associated with high resource utilization and poor outcomes. This study aimed to identify predictors of prolonged..

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Acute Kidney Injury After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract OBJECTIVES:  Acute kidney injury (AKI) occurs frequently in ICUs and is associated with poor outcomes. However, little is known about AKI in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) for..

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Extracorporeal Membrane Oxygenation Initiated in the Operating Room After Congenital Heart Surgery : A Single-Center Review of Survival Outcomes

Abstract Objectives To describe the incidence and survival of extracorporeal membrane oxygenation (ECMO) deployment in the operating room (OR) for failure to wean from cardiopulmonary bypass (CPB) after surgery for..

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Effect of Remimazolam on Hemodynamic Stability in Patients Undergoing Cardiac Surgery: A Grade-Assessed Systematic Review and Meta-Analysis of Randomized Controlled…

Abstract Hemodynamic instability during cardiac surgery, particularly procedures requiring cardiopulmonary bypass, increases the risk of mortality and adverse events. Conventional anesthetics such as propofol and etomidate have limitations in maintaining..

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Hydrogel nanocomposite-based breathable non-adhesive coating for oxygen sensing film used within extracorporeal perfusion system

Abstract Real-time, quantitative biosensing within extracorporeal perfusion (ECP) and extracorporeal membrane oxygenation (ECMO) systems is key to advancing this life-support technology beyond the hospital setting to emergency care. Measuring and..

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Follow-Up Brain MRI After Carotid Reconstruction or Ligation in Neonatal Venoarterial Extracorporeal Membrane Oxygenation: Single-Center Retrospective Cohort, 2009–2022

Abstract Objectives:  In neonates, the carotid artery can be ligated or reconstructed at the time of decannulation from venoarterial extracorporeal membrane oxygenation (VA-ECMO). However, there is a paucity of data..

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Kidney & extracorporeal support interactions: a narrative review

Abstract Purpose of review  Acute kidney injury (AKI) is common in critically ill patients, especially among those with severe and advanced organ failure. The use of extracorporeal support (ECS) is..

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Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy: a systematic review of the past decade (2014–2023)

Abstract Objective Extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) are often used together to treat critically ill patients. This systematic review aims to assess mortality and renal..

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The impact of arterial cannula direction in central venoarterial extracorporeal membrane oxygenation on aortic hemodynamic characteristics under various perfusion conditions

Abstract Objective To systematically evaluate the influence of cannula direction in central venoarterial extracorporeal membrane oxygenation (CVA ECMO) on aortic hemodynamics and oxygen transport through a multiparametric comparative analysis under..

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Veno-pulmonary extracorporeal membrane oxygenation for concomitant right ventricular and respiratory support: A systematic review of utilization patterns and outcomes

Abstract Background Veno-pulmonary artery extracorporeal membrane oxygenation (V-P ECMO) is a configuration of extracorporeal life support (ECLS) for patients with isolated or predominantly right ventricular (RV) failure and inadequate gas..

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Aortic Pulsatility Index Predicts Native Recovery in Patients With Cardiogenic Shock Supported by Intra-aortic Balloon Pumps

Abstract Background For decades, the intra-aortic balloon pump (IABP) has been a reliable and readily available pillar of therapy for cardiogenic shock (CS). However, no clinical markers have been validated..

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Cardiopulmonary Effects of Vasopressin Versus Norepinephrine in Cardiac Surgery Patients: a Single Cluster-Randomized Cross-over Trial

Abstract Background Laboratory research suggests that vasopressin restores systemic arterial pressure without significantly increasing pulmonary artery pressures, compared with norepinephrine. We therefore tested the hypotheses that treatment of intraoperative vasoplegia..

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Shear-induced dysregulation of haemostasis during extracorporeal membrane oxygenation: From cells to circuit

Abstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized in critical care globally to allow for adequate oxygenation in patients with cardiac and/or respiratory failure. Unfortunately, haemostatic complications – both..

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Antithrombin Supplementation in Extracorporeal Membrane Oxygenation: A Systematic Review With Meta-Analysis

Abstract Background The Extracorporeal Life Support Organization recommends daily antithrombin monitoring and supplementation to achieve > 50%–80% activity during extracorporeal membrane oxygenation (ECMO). Evidence supporting this practice is uncertain, and whether..

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Transfusion thresholds and other strategies for guiding red blood cell transfusion

Abstract Background The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions in anaemic patients remains an active area of research. Blood is a limited resource, and there..

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Functional Status Change in Pediatric Extracorporeal Membrane Oxygenation Survivors is Equivalent to Propensity-Matched Patients Managed Without Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is now commonly used to manage refractory pediatric cardiac or respiratory failure. Traditionally, ECMO has been associated with high morbidity. However, despite advancements in ECMO..

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State-of-the-Art Update in Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital Cardiac Arrest

Abstract ECPR Efficacy and Use: Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival and neurologic outcomes in refractory out-of-hospital cardiac arrest, with global adoption and center availability expanding significantly.

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Thresholds for Transfusion Practice During ECMO Support. A Systematic Review and Network Meta-Analysis

Abstract Purpose The benefits of adopting restrictive transfusion strategies, as opposed to a liberal approach, during extracorporeal membrane oxygenation (ECMO) remain unclear. This network meta-analysis aims to determine whether a..

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Evaluation of water loss during extracorporeal membrane oxygenation

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) can cause blood water loss due to insensible perspiration via oxygenators and plasma leakage. The accurate quantification of water loss is crucial for maintaining..

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Preoperative Endothelial Activation and Stress Index as a predictor of in-hospital mortality and postoperative complications in cardiac surgery with cardiopulmonary…

Abstract BACKGROUND  Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at risk for peri-operative complications, often linked to endothelial dysfunction. The Endothelial Activation and Stress Index (EASIX) has shown..

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Cost-effectiveness of eCPR: accounting for organ donation

Abstract Extracorporeal cardiopulmonary resuscitation (eCPR) is a highly resource-intensive procedure, and its cost-effectiveness remains a subject of debate []. Hospital-based eCPR for refractory out-of-hospital cardiac arrest has been shown to..

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Experience With Pediatric Extracorporeal Membrane Oxygenation (ECMO) Standby at Two High-Volume Centers

Abstract Extracorporeal membrane oxygenation (ECMO) can provide an option for high-risk procedures that may result in cardiopulmonary collapse. The indications for ECMO standby are not well delineated. We describe the..

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Effects of noradrenaline, vasopressin, phenylephrine or metaraminol on kidney and brain microcirculation in ovine cardiopulmonary bypass: a randomised trial

Abstract Introduction Intra-operative hypotension is common during cardiopulmonary bypass and may contribute to tissue hypoxia. Tissue hypoxia has been linked to the development of postoperative kidney and brain injury. Vasopressors..

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Thromboelastography in Children Undergoing Extracorporeal Membrane Oxygenation

Abstract Background Children undergoing extracorporeal membrane oxygenation (ECMO) are at risk of hematologic and coagulation complications, including intracranial hemorrhage. Thromboelastography is used to monitor anticoagulation in patients receiving ECMO, but..

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Prospective Observational Study Comparing Systemic Inflammatory Responses Across Different Perfusion Systems During Isolated On-Pump Coronary Artery Bypass Grafting

Abstract Objectives Minimal invasive Extracorporeal Circulation (MiECC) and Hybrid System (HS) have been introduced to potentially reduce the inflammatory response compared to conventional Cardiopulmonary Bypass (cCPB). The HS combines elements..

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Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk

Abstract Importance  Postoperative red blood cell transfusion guidelines recommend transfusion for hemoglobin levels less than 7 g/dL. However, the safety of this strategy in patients at high risk of cardiac events..

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Ethical Considerations for Patients Requiring Extracorporeal Cardiopulmonary Resuscitation

Abstract Immediate recognition of cardiac arrest and the initiation of cardiopulmonary resuscitation (CPR) can significantly improve survival chances. The use of extracorporeal membrane oxygenation during CPR (eCPR) could further enhance..

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Is body mass index associated with hypoxic-ischemic brain injury risk in extracorporeal cardiopulmonary resuscitation?

Abstract Aim To characterize the impact of BMI (body mass index) on HIBI (hypoxic-ischemic brain injury) in patients receiving ECPR, with the hypothesis that elevated BMI is associated with increased..

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Prolonged intra-aortic balloon pump support successfully reversed severe pulmonary hypertension prior to heart transplantation

Abstract Background Heart transplantation remains the gold standard for the treatment of end-stage heart failure, but severe pulmonary hypertension (PH) poses a significant challenge due to the increased risk of..

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