Monthly Archives: septiembre 2026

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Retrograde Lower Body Perfusion Is Associated with Reduced Acute Kidney Injury in Stage II Palliation for Hypoplastic Left Heart Syndrome

Abstract Objective Acute kidney injury (AKI) complicates pediatric cardiac surgery, particularly in single-ventricle palliation. While retrograde lower body perfusion (LBP) has been associated with a renal-protective signal during aortic arch..

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Enhanced antithrombogenic performance of microfluidic oxygenators through dual bioactive surface modification for an artificial placenta system

Abstract In recent years, artificial placenta systems have been developed for the clinical treatment of infant respiratory distress syndrome (RDS). Their use requires systemic anticoagulation to prevent clotting during treatment...

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Design and in vitro evaluation of a parallel gas-exchange chambers oxygenator with reduced hemolysis and pressure drop

Abstract Background: Hemolytic complications remain a major limitation of membrane oxygenators in clinical support. Compared with human lungs, most commercial oxygenators generate substantial pressure drops and high shear stress, increasing..

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Randomized pilot trial of intraoperative hemoadsorption in clopidogrel treated patients undergoing urgent coronary artery bypass grafting

Abstract Background Patients receiving clopidogrel who undergo urgent CABG before the recommended 5-day washout period are at increased risk of perioperative bleeding. This study evaluated whether intraoperative hemoadsorption can reduce..

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Artificial Intelligence for Predicting Perioperative Outcomes in Cardiac Surgery: A Systematic Review

Abstract Objective: Cardiac surgery carries a significant risk of complications and mortality. Artificial intelligence (AI), particularly machine learning (ML), is increasingly being explored to enhance perioperative risk prediction and support..

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Navigating anticoagulation in heart transplantation with thrombin–antithrombin complex: when conventional monitoring fails

Abstract Background Heart transplant recipients often face the clinical dilemma of coexisting bleeding and thrombotic risks postoperatively. Conventional anticoagulation monitoring parameters (e.g., platelet count, fibrinogen, D‑dimer, and anti‑Xa activity) frequently..

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Blood Glucose Variability and Postoperative Organ Function in Coronary Artery Bypass Grafting: A Prospective Cohort Study of Microcirculatory Perfusion and…

Abstract Objectives Coronary heart disease remains the leading cause of cardiovascular morbidity and mortality. The relationship between perioperative blood glucose variability (BGV), microcirculatory changes, and subsequent organ dysfunction after coronary..

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Impact of red blood cell transfusion on clinical outcomes after cardiovascular surgery: a reconstructed time-to-event meta-analysis

Abstract Background The impact of perioperative red blood cell transfusion on long-term outcomes after cardiovascular surgery remains controversial. This meta-analysis of reconstructed time-to-event data aimed to evaluate the association between..

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AI integration in healthcare simulation debriefing: support or substitute?

Abstract Debriefing is widely recognised as a central mechanism for learning within healthcare simulation, enabling learners to reflect on clinical actions, decision-making, and team interactions. However, high-quality debriefing is resource-intensive,..

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Evaluation of Activated Clotting Time Response to Unfractionated Heparin in Vascular Surgery: An Observational Study

Abstract Objectives Activated clotting time (ACT) is widely used to monitor intraoperative anticoagulation with unfractionated heparin (UFH) during vascular surgery, but the most informative ACT-derived metric and the optimal approach..

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V̇co2: the essential underpinning to homeostatic control of breathing

Abstract This essay addresses the fundamental mechanism underlying the precise regulation of PaCO2 during steady states of air-breathing eupnea and hyperpnea. First, an argument is made for CO2/H+ chemoreception as an important compensatory..

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Distinct goal-directed perfusion signatures in donation after brain death versus circulatory death heart transplantation

Abstract Background Continuous oxygen extraction ratio (O2ER) monitoring during cardiopulmonary bypass is an emerging strategy to support goal-directed perfusion (GDP) during heart transplantation (HT). Because donation after circulatory death (DCD)..

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Piecing together the alveolar-capillary unit: arterial-venous capillary polarization

Abstract Pulmonary capillary endothelial cells (ECs) form a highly specialized vascular interface that sustains gas exchange and organismal survival across species. Recent advances in single-cell transcriptomics and lineage tracing have..

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Imbalance between oxygen delivery and consumption during cooling and rewarming phases of cardiopulmonary bypass and association with hyperlactatemia in total…

Abstract Background Inadequate oxygen perfusion during cardiac surgery increases risk of postoperative complications. In order to optimize perfusion strategies, the aim of this exploratory study was to investigate oxygen delivery,..

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The intrinsic cardiac nervous system is essential for cardiac function and survival

Abstract The intrinsic cardiac nervous system (ICNS) is a key node in heart-brain communication and an emerging target for cardiac therapy, yet its physiological importance and functional organization remain poorly..

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Sonorheometry Quantra QPlus Characteristics in Adult Cardiac Surgical Patients: An Observational Cohort Study

Abstract BACKGROUND: Validation of the Quantra QPlus sonorheometry cartridge (Hemosonics Corporation) in cardiac surgical patients is limited. The primary aim of our study was to quantify the accuracy of the..

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Risk factors and outcomes of early postoperative complications following congenital heart surgery: a retrospective study at a tertiary care hospital…

Abstract Introduction Congenital Heart Disease (CHD) remains a major health challenge globally, with surgical interventions being the primary treatment modality for many defects. While advancements in cardiac surgery have improved..

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Postoperative anaemia and long-term survival following cardiac surgery: a multicentre, retrospective, observational study

Abstract Introduction Pre-operative anaemia is associated with adverse outcomes following cardiac surgery. However, the prognostic impact of postoperative anaemia is characterised incompletely. We examined whether anaemia at hospital discharge independently..

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Mortality-related predictors in patients receiving extracorporeal membrane oxygenation after coronary artery bypass grafting: a retrospective study

Abstract Background This study aimed to evaluate in-hospital mortality and to identify predictors of mortality in coronary artery bypass grafting (CABG) patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. Methods..

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Incidence and Temporal Changes of Transfusion and Coagulation Management in Cardiac Surgery: Insights From the Netherlands Heart Registration

Abstract Objectives To describe perioperative transfusion rates, hospital variability, temporal trends, and the association between red blood cell (RBC) transfusion and predefined risk factors in Dutch cardiac surgery. Design Nationwide..

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Efficacy and safety of prothrombin complex concentrate versus fresh frozen plasma in adult patients undergoing cardiac surgery: a systematic review…

Abstract Background Postoperative bleeding is a common and potentially life-threatening complication following cardiac surgery, often exacerbated by multifactorial coagulopathy from cardiopulmonary bypass, hypothermia, and platelet dysfunction. While fresh frozen plasma..

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Designing a Cardiac Arrest System That Includes Extracorporeal Cardiopulmonary Resuscitation: A Contemporary Review

Abstract Extracorporeal cardiopulmonary resuscitation for refractory out‐of‐hospital cardiac arrest is increasingly used, with survival rates up to ≈30% reported in select highly organized systems, although outcomes vary widely across programs...

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Predictive value of oxygen delivery and regional oxygen saturation during cardiopulmonary bypass for cardiac surgery-associated acute kidney injury in neonates…

Abstract  Objective: To explore the predictive value of intraoperative oxygen delivery (DO2) and renal regional oxygen saturation (rSO2 ) during cardiopulmonary bypass (CPB) for cardiac surgery-associated acute kidney injury (CS-AKI)..

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Preoperative Stabilization With Left Atrial Venoarterial Extracorporeal Membrane Oxygenation Before Salvage Valve Surgery in Cardiogenic Shock

Abstract Patients undergoing salvage cardiac surgery experience markedly elevated mortality, often exceeding the risk predicted by the Society of Thoracic Surgeons Predicted Risk of Mortality score. These patients are typically..

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Predictive value of preoperative hematologic inflammation indices (NLR, PLR, SII) and clinical risk factors in predicting postoperative pulmonary complications after…

Abstract Background Pulmonary complications after coronary artery bypass surgery continue to be a significant problem, affecting 5–20% of patients, prolonging hospital stays and increasing costs. In this study, we investigated..

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Amino acids for the prevention of acute kidney injury after cardiac surgery: a narrative review of trials and meta-analyses

Abstract Acute kidney injury (AKI) is one of the most common serious complications after cardiac surgery. Although many causes and risk factors have been identified, effective measures to prevent AKI..

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Partial cardiopulmonary bypass in thoracoabdominal aorta repair: a safe alternative in a low-volume center

Abstract Objective To describe postoperative outcomes with the use of partial CPB for thoracoabdominal aortic repair. Methods We included all the patients who underwent programmed thoracoabdominal aortic procedures in which..

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Pragmatic Assessment of VA-ECMO Decannulation Readiness After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract Background Readiness for venoarterial-extracorporeal membrane oxygenation (VA-ECMO) decannulation after extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) remains poorly defined. Objectives The objective of the study was to..

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Partial carina resection, reconstruction, and left pneumonectomy under median sternotomy combined with cardiopulmonary bypass: a case report

Abstract Background There is limited clinical data to guide surgical decisions for ACC with extensive carinal involvement in the left main bronchus. In this case, it is shown that median..

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Brain Death Determination During VA-ECMO After Pediatric Cardiac Surgery: A Case-Based Analysis of the 2023 Unified Consensus

Abstract Background Determination of brain death/death by neurologic criteria (BD/DNC) in patients supported with extracorporeal membrane oxygenation (ECMO) is particularly challenging due to extracorporeal carbon dioxide clearance, which may interfere..

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