Pediatric

Perfusfind S.L.

Abstract Background: Among infants undergoing cardiac surgery, AKI may affect as many as 40% of this population and carries an unfavorable prognosis. A range of contributors has been implicated, including early age, cyanotic physiology, and extended time on cardiopulmonary bypass (CPB). Nadir-indexed oxygen delivery (DO2) is an important determinant for early..

Perfusfind S.L.

Abstract BACKGROUND We sought to determine if modified ultrafiltration (MUF) in the current era was associated with improved outcomes after neonatal cardiopulmonary bypass (CPB). METHODS Retrospective analysis of the PC4/NEPHRON dataset from 22 centers (2015-18). Neonates were stratified by MUF use and outcomes were compared. Multivariable regression models were adjusted..

Perfusfind S.L.

Abstract Lactate clearance is a key marker of oxygen delivery after neonatal cardiac surgery. While higher hematocrit (HCT) is often targeted to optimize oxygen delivery, its relationship with postoperative lactate clearance remains unclear. We hypothesized that supraphysiologic initial HCT may decrease lactate clearance. To assess whether higher initial postoperative HCT..

Perfusfind S.L.

      Dr.Sam Zeraatian Nejad Davani,  Cardiovascular and Thoracic Surgeon Transplant and Thoracic Organs Recovery Surgeon.  Director of Georgia Atlanta Procure on Demand Thoracic Organs Transplant and Procurement Surgery.                      

Perfusfind S.L.

Abstract Introduction Congenital Heart Disease (CHD) remains a major health challenge globally, with surgical interventions being the primary treatment modality for many defects. While advancements in cardiac surgery have improved survival rates, early postoperative complications continue to pose risks, particularly in settings with limited resources like Kenya. The study aimed..

Perfusfind S.L.

Abstract  Objective: To explore the predictive value of intraoperative oxygen delivery (DO2) and renal regional oxygen saturation (rSO2 ) during cardiopulmonary bypass (CPB) for cardiac surgery-associated acute kidney injury (CS-AKI) in neonates with congenital heart disease (CHD). Methods: A total of 235 neonates who underwent CPB-assisted cardiac surgery were enrolled..

Perfusfind S.L.

Abstract In children, validated tools to monitor anaesthetic depth are lacking. In routine practice, dosing of volatile agents relies on surrogate markers such as minimum alveolar concentration and autonomic responses. In noncardiac surgery, sevoflurane administration is typically guided by its end tidal concentration (FeSevo), which closely reflects cerebral partial pressure and..

Perfusfind S.L.

Abstract Background Pediatric patients undergoing cardiac surgery are at risk for developing positive cumulative fluid balance (CFB). Our goal was to study postoperative CFB in this population, its explanatory variables, and its effect on clinical outcomes during pediatric intensive care unit (PICU) stay and follow-up. Methods Retrospective single center study..

Perfusfind S.L.

Abstract Objectives To determine whether individualized heparin dosing guided by a heparin dose-response (HDR) curve is noninferior to conventional weight-based dosing in achieving target activated clotting time (ACT) of ≥480 seconds before cardiopulmonary bypass (CPB) and to compare total heparin and protamine requirements, postoperative blood loss, and transfusion needs in..

Perfusfind S.L.

Abstract Background Children undergoing high-risk cardiac surgery face significant postoperative morbidity and mortality risk, and early recognition of impaired systemic perfusion is critical. Current monitoring modalities, such as lactate, central venous oxygen saturation, and near-infrared spectroscopy, are indirect surrogates of cardiac output and are either invasive or have limited predictive..