Pediatric

Perfusfind S.L.

Abstract Background Drawing on more than 30 years of valuable expertise in in-vitro, in-vivo, and clinical trials, we report the key findings of our institutional research on pulsatile cardiopulmonary bypass (CPB). Methods A detailed search was performed in the National Institutes of Health National Library of Medicine, focusing on the..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) is a common complication after pediatric cardiac surgery using cardiopulmonary bypass (CPB). This study evaluated renal regional oxygen saturation (R-rSO₂), measured via near-infrared spectroscopy (NIRS), as an AKI predictor. Methods 120 pediatric patients undergoing CPB-assisted congenital heart surgery were prospectively enrolled. Continuous intraoperative R-rSO₂..

Perfusfind S.L.

Abstract Objectives This quality improvement project aimed to enhance operating room efficiency in a newly established paediatric cardiac operating room by focusing on key performance indicators (KPI), including (1) first case on-time start (FCOTS), (2) turnover time (TOT), and (3) case cancellation rate through targeted interventions. Methods This initiative was..

Perfusfind S.L.

Abstract Design Apixaban is a direct oral anticoagulant that inhibits factor Xa. Our objective was to examine the effect of apixaban on perioperative transfusion requirements in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass. Setting Quaternary children’s hospital. Participants Children with congenital or acquired heart disease who received apixaban less..

Perfusfind S.L.

Abstract Background/Objectives: In the present study, we hypothesized that cardiac surgery in pediatric patients with congenital heart disease (CHD) leads to profound endothelial glycocalyx degradation, measured as the increase in plasma syndecan-1 concentration, and that this endothelial damage is more pronounced in patients with cyanotic CHD.  Methods: A total of..

Perfusfind S.L.

Abstract Racial and ethnic disparities and language barriers coexist with inequities in a child’s educational, environmental, and economic opportunity. We evaluated the association between surgical outcomes and a composite child neighborhood opportunity index (COI), race and ethnicity, and language barriers among children undergoing congenital heart surgery. Utilizing the Society of..

Perfusfind S.L.

Abstract The number of potential pediatric heart transplant recipients continues to exceed the number of donors, and consequently the waitlist mortality remains significant. Despite this, around 40% of all donated organs are not used and are discarded. This document (62 authors from 53 institutions in 17 countries) evaluates factors responsible..

Perfusfind S.L.

Abstract Background Donor discard rates for pediatric heart transplant (HT) remain high (≈40%), often driven by concerns about elevated donor troponin levels. This study evaluated the association between peak donor troponin levels, donor troponin trends, and post transplant survival among pediatric HT recipients. Methods Children (aged <18 years at listing) who..

Perfusfind S.L.

Abstract Background:  Acute kidney injury (AKI) is a frequent complication of congenital heart surgery with cardiopulmonary bypass (CPB) in pediatric patients, contributing to significant morbidity and mortality. Aim:  To determine the prevalence and perioperative predictors of AKI after pediatric CPB. Methods:  In this single-center retrospective cohort study, medical records of..

Perfusfind S.L.

Abstract Introduction Heparin induced thrombocytopenia (HIT) with in paediatric population is rare and subsequent anticoagulation management is challenging. Bivalirudin is a viable alternative to heparin for anticoagulating paediatric patients with HIT, though clinical data are limited. We describe the successful management of anticoagulation with bivalirudin from diagnosis through Extracorporeal Membrane..