Pediatric

Perfusfind S.L.

Abstract Background Delayed sternal closure (DSC) is a well-established management strategy following complex congenital cardiac surgery that is used to mitigate postoperative hemodynamic and respiratory instability. It is mostly used in neonates requiring prolonged cardiopulmonary bypass (CPB), long aortic cross-clamp times, or deep hypothermic circulatory arrest who are predisposed to..

Perfusfind S.L.

Abstract To investigate the feasibility of regional oxygen saturation (rSO2) monitoring for preventing acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) caused by cardiopulmonary bypass (CPB) in infants undergoing ventricular septal defect (VSD) closure. This study included 49 infants who underwent VSD closure between January 2012 and December 2023. Patients..

Perfusfind S.L.

Abstract Background There is geographic disparity in the provision of Pediatric and Congenital Heart Disease (PCHD) services; Africa accounts for only 1% of global cardiothoracic surgical capacity. Methods We conducted a survey of PCHD services in Africa, to investigate institution and national-level resources for pediatric cardiology and cardiothoracic surgery. Results..

Perfusfind S.L.

Abstract Background: The gold standard for treatment of patients with end-stage heart failure remains . Time spent on the active waiting list, notably for  patients, contributes to alarmingly high mortality. Donation after circulatory death (DCD) marks an evolution in  that has proven to expand the donor pool and shorten waitlist times in adult..

Perfusfind S.L.

Abstract Objective To describe cardiac arrest during anesthesia care provided by a pediatric cardiac anesthesiologist in patients with congenital heart disease and identify predictors of outcome. Design Retrospective chart review. Setting Quaternary children’s hospital. Participants Patients with congenital cardiac disease undergoing cardiac procedures or imaging between January 2016 and December..

Perfusfind S.L.

Abstract Purpose Extracorporeal cardiopulmonary resuscitation (ECPR) is an advanced resuscitation therapy for cardiopulmonary arrest refractory to standard CPR. ECPR treatment recommendations are not supported by strong evidence, and institutional criteria for its application are rare, challenging decision-making. We performed a decisional needs assessment among providers engaged in ECPR decisions at..

Perfusfind S.L.

Abstract This study aimed to assess whether the proinflammatory markers procalcitonin (PCT), C-reactive protein (CRP), or interleukin 6 (IL-6) are associated with mortality in neonates with congenital diaphragmatic hernia (CDH) requiring extracorporeal membrane oxygenation (ECMO). Congenital diaphragmatic hernia neonates receiving venovenous ECMO between December 2012 and June 2022 were retrospectively..

Perfusfind S.L.

Abstract Importance  Studies suggest that everolimus may reduce the risk of rejection, cardiac allograft vasculopathy (CAV), chronic kidney disease (CKD), and cytomegalovirus (CMV) after heart transplant. Everolimus use is controversial because of data demonstrating higher infection deaths when everolimus is introduced de novo after transplant. It is unclear whether everolimus is..

Perfusfind S.L.

Abstract Nutritional support in pediatric patients receiving extracorporeal membrane oxygenation (ECMO) therapy is controversial. Although ECMO is increasingly used in pediatric intensive care units, there is no consensus on the optimal approach for nutrient prescription in this patient population. It is imperative to understand that this population experiences severe metabolic..

Perfusfind S.L.

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a notably common complication in pediatrics, with an incidence rate ranging from 15 to 64%. This rate is significantly higher than that observed in adults. Currently, there is a lack of substantial evidence regarding the association between intraoperative blood pressure variability..