Abstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and outcomes in pediatric patients requiring veno-venous (VV) ECLS. Methods: Retrospective single-center study at an academic children’s hospital, Children’s Healthcare..
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Abstract Introduction This study aims to describe laboratory and clinical factors associated with thrombotic events during prolonged pediatric extracorporeal membrane oxygenation. Methods A secondary analysis of a multi-center prospective study performed between 2012 and 2014. Patients under the age of 19 years that received extracorporeal membrane oxygenation for at least 4 days..
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Abstract Objectives To ascertain the dosage of bivalirudin in neonates and infants undergoing arterial switch operation on integrated extracorporeal membrane oxygenation–cardiopulmonary bypass (CPB) circuit. Design Pilot study. Setting A tertiary care hospital. Participants Ten neonates and infants with transposition of great arteries undergoing an arterial switch operation Interventions The patients..
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Abstract Objectives: Blood lactate concentration ([Lac]b) reflects the balance among production, clearance (Cl[Lac]), and volume of distribution. We have observed dramatic improvement in [Lac]b in critically ill patients after starting support with extracorporeal membrane oxygenation (ECMO) and discontinuing vasopressors. Here, we evaluated such [Lac]b profiles to develop a mathematical model of recovery..
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Abstract To evaluate the impact of hospital-acquired infections ( HAIs ) on the prognosis of neonates treated with extracorporeal membrane oxygenation (ECMO) and analyzing related prognostic indicators, we conducted a systematic review and meta-analysis. Databases such as PubMed, Web of Science, Embase, and the Cochrane Library from the inception of..
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Abstract Extracorporeal membrane oxygenation (ECMO) is an important rescue strategy for neonates with severe cardiorespiratory failure, yet its role in the management of hypoxic–ischemic encephalopathy (HIE) remains subject to debate. Historically, clinicians have been reluctant to offer ECMO to infants with significant neurological injury because of concerns related to poor..
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Abstract OBJECTIVES Acute kidney injury commonly complicates congenital heart surgery with cardiopulmonary bypass, increasing morbidity and mortality. This study aimed to evaluate risk factors for postoperative acute kidney injury and its impact on outcomes after the Norwood procedure. METHODS Neonates undergoing the Norwood procedure from 2001 to 2022 were reviewed...
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Abstract Purpose The purpose of this systematic review was to identify the efficacy of cell salvage in adult and pediatric spinal surgery. Methods A comprehensive systematic review of four biomedical databases was conducted to identify study articles of interest. Articles from original studies were compiled for the composition of this..
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Abstract Aims Pediatric cardiac arrest is associated with high mortality and significant morbidity among survivors. International guidelines for prognostication remain limited due to small heterogeneous patient populations, variable post-return of circulation diagnostics, and insufficient long-term follow-up. Pediatric Resuscitation Prognostication and Outcomes Registry (PROGNOSE) is a Dutch nationwide, multicenter registry aiming..
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Abstract Poor or worsening functional status of lung transplant (LTx) candidates is a key risk factor for waitlist and post-transplant mortality. As more critically ill adults and children are listed for LTx, the use of extracorporeal membrane oxygenation (ECMO) as bridge to LTx is also increasing. Sustaining optimal functional status..
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