Pediatric

Perfusfind S.L.

Abstract Introduction Heparin induced thrombocytopenia (HIT) with in paediatric population is rare and subsequent anticoagulation management is challenging. Bivalirudin is a viable alternative to heparin for anticoagulating paediatric patients with HIT, though clinical data are limited. We describe the successful management of anticoagulation with bivalirudin from diagnosis through Extracorporeal Membrane..

Perfusfind S.L.

Abstract Objective To investigate the association of Tau protein levels with postoperative evidence of neural injury following cardiopulmonary bypass (CPB) in pediatric cardiac surgery patients. Methods One hundred forty-four consecutive pediatric cardiac surgery patients were recruited. Whole blood (3 mL) was collected in EDTA tubes from an arterial line at..

Perfusfind S.L.

Abstract Hyperoxia in pediatric cardiopulmonary bypass patients is associated with adverse effects, including reoxygenation injury, increased mortality, heightened inflammatory response, and cerebral injury. Although prior research has demonstrated a correlation between these adverse effects and hyperoxia during cardiac surgery, definitions of “hyperoxia’ vary across the literature. This scoping review synthesizes..

Perfusfind S.L.

Abstract Background:Infants with CHD who undergo cardiopulmonary bypass surgery are at risk of impaired growth and neurodevelopment. However, few studies have thoroughly investigated the risk factors for growth and neurodevelopmental impairments, particularly with respect to the timing of the initial surgical intervention. Methods:We retrospectively analysed term singleton infants with CHD..

Perfusfind S.L.

Abstract Background Children with congenital heart disease are at risk for poor neurodevelopment. The gut microbiome may influence neurodevelopmental outcomes through the gut-brain axis. This study investigated the association of early-life gut microbiome with neurodevelopmental outcomes. Methods A prospective cohort study was conducted in the cardiac intensive care unit. Fecal..

Perfusfind S.L.

Abstract Background Acute Kidney Injury (AKI) is a frequent post-operative complication following cardiac surgery in the clinical setting. Iron metabolism disorders are a key cause of kidney injury during the ischemia-reperfusion (IR) process. However, the role of iron metabolites in prediction of AKI remains unidentified. This study investigates the roles..

Perfusfind S.L.

Abstract Objectives Neonates with complex congenital heart disease (CHD), in particular newborns with hypoplastic left heart syndrome (HLHS) or transposition of the great arteries (TGA), may show brain pathologies and altered brain growth after birth. Our prospective study investigates brain volumes and immature brain structures in these patient groups compared..

Perfusfind S.L.

LVAD Implantation in Pediatric Population inflow from LV and outflow to Ascending Aorta.   LVAD Implantation in the Pediatric Population   By Sam Zeraatiannejaddavani, MD   ⸻   A — Assessment & Indications   1. Clinical Indications •Refractory Stage D heart failure despite optimal medical therapy (NYHA IV / INTERMACS..

Perfusfind S.L.

Abstract Background Children with heart disease and cardiopulmonary failure may be supported with extracorporeal membrane oxygenation (ECMO) for stabilization before cardiac surgery. This study describes their epidemiology and outcomes. Methods The Society of Thoracic Surgeons Congenital Heart Surgery Database was queried for patients aged <18 years who underwent ECMO cannulation..

Perfusfind S.L.

Abstract Objectives:  To derive and externally validate supervised machine learning (ML) models predictive of cardiac surgery-associated acute kidney injury (CS-AKI). Design:  Retrospective cohort analysis. Setting:  Multicenter (4), cardiac surgical centers from January 2019 to February 2022. Patients:  Seven days to 18 years old who had undergone cardiac surgery. Interventions:  None...