Pediatric

Perfusfind S.L.

Abstract Objective:This study aimed to evaluate school-age neurodevelopmental outcomes among children with single ventricle heart disease who underwent neonatal Norwood operation with regional cerebral perfusion compared to deep hypothermic circulatory arrest. Additionally, we aimed to identify predictors of school-age development, including early developmental measures. Study design:Patients enrolled in a prospective..

Perfusfind S.L.

Abstract Allogeneic red blood cells (RBCs) are commonly used for cardiopulmonary bypass (CPB) circuit priming in congenital heart surgery. While convection-based pre-bypass ultrafiltration (PBUF) corrects acid–base, electrolyte, and metabolite imbalances, its efficacy in removing RBC cytokines/chemokines remains unclear. In a prospective observational study, 22 children (median age: 4.1 months) undergoing congenital..

Perfusfind S.L.

Abstract Background Despite the widespread adoption of selective antegrade cerebral perfusion (SACP) for neonatal aortic arch reconstruction, significant variability in techniques persists across institutions, thus reflecting limited supporting data and lack of consensus on best practices. This review aimed to characterize the use of SACP in the extant literature comprehensively..

Perfusfind S.L.

Abstract Therapeutic plasma exchange (TPE) in pediatric patients presents many challenges, including management of a large extracorporeal volume (ECV) and calcium replacement for patients who may not be able to express signs of hypocalcemia or other associated adverse events with a large ECV. Pediatric patients who are critically ill on..

Perfusfind S.L.

Abstract Background The experience of a percutaneous microaxial (Impella)  in children with  is limited. The primary objective of this study was to review our institutional clinical outcomes of Impella use in children with cardiogenic shock. Methods This is a single-center retrospective study of all adult-sized children who underwent Impella implantation from June..

Perfusfind S.L.

Abstract Aims Academic achievement of children with congenital heart disease (CHD) has not been comprehensively studied across the entire CHD severity spectrum. Methods and results Through nationwide registries, we identified all children with CHD who reached 16 years of age and matched each child with CHD to controls who attended..

Perfusfind S.L.

Abstract Congenital diaphragmatic hernia (CDH) is a rare and severe malformation that can lead to life-threatening postnatal physiological challenges which may require lifesaving extracorporeal membrane oxygenation (ECMO) support, sometimes more than once. However, the benefits of multiple ECMO courses remain uncertain. Data on all patients with CDH supported on ECMO..

Perfusfind S.L.

Abstract Background Young patients may survive accidental deep hypothermia with prolonged asystolic circulatory arrest because of protective effects of cold. Case Summary An 8-year-old boy fell through pond ice and was submerged for ≥147 minutes. Nadir peripheral body temperature was 7 °C (45 °F). After rewarming with extracorporeal membrane oxygenation,..

Perfusfind S.L.

Abstract Background Delayed sternal closure (DSC) is a well-established management strategy following complex congenital cardiac surgery that is used to mitigate postoperative hemodynamic and respiratory instability. It is mostly used in neonates requiring prolonged cardiopulmonary bypass (CPB), long aortic cross-clamp times, or deep hypothermic circulatory arrest who are predisposed to..

Perfusfind S.L.

Abstract Background There is geographic disparity in the provision of Pediatric and Congenital Heart Disease (PCHD) services; Africa accounts for only 1% of global cardiothoracic surgical capacity. Methods We conducted a survey of PCHD services in Africa, to investigate institution and national-level resources for pediatric cardiology and cardiothoracic surgery. Results..