Pediatric

Perfusfind S.L.

Abstract Introduction Bleeding and thrombosis are major causes of morbidity and mortality in pediatric extracorporeal membrane oxygenation (ECMO), yet their evolving, time-dependent risks remain poorly defined. This study evaluated clinical predictors of bleeding and thrombotic events using time-to-event analysis. Methods A retrospective cohort study was conducted using the Pediatric ECMO..

Perfusfind S.L.

Abstract Extubation of select neonatal and pediatric patients supported with extracorporeal membrane oxygenation (ECMO) may avoid ventilator-induced lung injury, decrease neurosedative exposure, and improve rehabilitation. A single-center retrospective cohort study was performed to describe our experience with extubation of ECMO patients in the cardiac intensive care unit (CICU), pediatric intensive..

Perfusfind S.L.

Abstract Background Cardiac allotransplantation is the optimal treatment for end-stage heart failure. However, organ supply remains the principal issue affecting patients. Pediatric patients present unique challenges resulting in long wait-list times and increased mortality. Donation after circulatory death with normothermic regional perfusion represents a method to increase the number of..

Perfusfind S.L.

Abstract Background Children undergoing cardiopulmonary bypass (CPB) surgery are vulnerable to bleeding and often require transfusions. Pathogen-reduced (PR) platelets may reduce microbial contamination but are associated with decreased platelet count increments and increased transfusions. We sought to evaluate hemostasis in children undergoing CPB surgery receiving PR platelets vs large-volume delayed..

Perfusfind S.L.

Abstract Background: To investigate the factors that influence blood transfusions after neonatal cardiac surgery and their association with prolonged mechanical ventilation (PMV) to provide a basis for optimizing blood transfusion strategies. Methods: This study retrospectively analyzed the clinical data of 202 neonates who had undergone cardiac surgery with cardiopulmonary bypass..

Perfusfind S.L.

Abstract The emergence of large language models (LLMs) opens new horizons to leverage, often unused, information in clinical text. Our study aims to capitalise on this new potential. Specifically, we examine the utility of text embeddings generated by LLMs in predicting postoperative acute kidney injury (AKI) in paediatric cardiopulmonary bypass..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) and dysnatremia following pediatric cardiac surgery are common conditions associated with worse outcomes. While the multifactorial etiology of AKI is well-known, the role of concomitant dysnatremia is limited. This study aims to describe the occurrence of AKI, its association with the length of stay..

Perfusfind S.L.

Abstract Background To evaluate the effect and safety of modified ultrafiltration warming technology during pediatric congenital heart disease (CHD) surgery. Methods A retrospective analysis included 68 children (<1 year) who underwent CHD correction surgery with cardiopulmonary bypass (CPB) and modified ultrafiltration (MUF). Patients were divided into a warmed MUF group..

Perfusfind S.L.

Abstract Digital ischemia following extracorporeal membrane oxygenation (ECMO) therapy is a known complication with potential devastating long-term sequela. Onabotulinum toxin type A (BTX-A) has been demonstrated to be effective for digital ischemia in adults with Raynaud’s phenomenon. The objective of this study is to describe the use of BTX-A in..

Perfusfind S.L.

Abstract Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant deaths in this population. Donation after circulatory death (DCD) with normothermic regional perfusion has the potential to increase the donor..