Abstract While cardiogenic shock (CS) is classically defined by primary cardiac dysfunction leading to impaired macrocirculatory variables—such as hypotension, reduced cardiac output (CO), and diminished left ventricular ejection fraction—growing evidence..
Read MoreAbstract Objectives Acute kidney injury (AKI) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). This study investigated whether cell-free hemoglobin (CFHb) levels after CPB are associated with..
Read MoreAbstract Rationale In acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) without invasive mechanical ventilation (IMV) is particularly challenging. Objectives To study ARDS patients treated with ECMO to avoid..
Read MoreAbstract Background and Objectives: Extracorporeal membrane oxygenation (ECMO) provides temporary respiratory or circulatory support when conventional therapies fail. Some patients do not recover and are not candidates for transplant or..
Read MoreAbstract Background Gas embolism (GE) occurs when gas enters into the circulation. Whilst small quantities of gas may be harmless, massive, or systemic GE may be life-threatening, when associated with..
Read MoreAbstract Background Data on the outcome of veno-arterial extracorporeal membrane oxygenation (V-A-ECMO) support as a bridge to replacement therapies are scarce. Objectives We investigated the outcome of V-A-ECMO support after..
Read MoreAbstract Background: Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..
Read MoreAbstract Objectives Los Angeles County initiated an extracorporeal cardiopulmonary resuscitation (eCPR) program to transport patients with refractory shockable out-of-hospital cardiac arrest (OHCA) to dedicated eCPR-capable centers (ECCs). The impact of..
Read MoreAbstract For many tertiary care hospitals, not offering extracorporeal membrane oxygenation (ECMO) is increasingly difficult to justify. Choosing not to offer ECMO means patients who could survive are instead transferred,..
Read MoreAbstract Introduction Adverse neurological complications, including postoperative delirium (POD) and stroke, remain one of the major risks after cardiac surgery. A lack of comprehensive knowledge about their causes and neuroprotective strategies..
Read MoreAbstract While extracorporeal membrane oxygenation (ECMO) case volume continues to increase [, ], management of patients receiving ECMO remains technically challenging [, ]. Iatrogenic injury is a potential contributor to complications and..
Read MoreEvolving Concepts in Anticoagulation for VV-ECMO, VA-ECMO, and ECPR Moderator: Peter Schellongowski Speakers and Schedule: Anticoagulation and antiplatelets in VA ECMO Christophe Vandenbriele (London/United Kingdom) Anticoagulation and antiplatelets in..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (ECPR) offers a life-saving option for select patients with refractory cardiac arrest, yet a substantial proportion suffer devastating neurological injury and die despite extracorporeal support. In..
Read MoreAbstract Purpose Pediatric patients undergoing cardiac surgery are at risk of developing postoperative acute kidney injury (AKI). We hypothesized that a reduction in intraoperative renal (SrO2) or cerebral (ScO2) tissue..
Read MoreAbstract Background Extracorporeal Life Support (ECLS) services are characterised by variability in resource availability, specific expertise, device management and team organisation, especially regarding the role of perfusionists. This international survey..
Read MoreAbstract Background We implemented a preoperative screening brain magnetic resonance imaging (MRI) protocol for neonates undergoing cardiac surgery. The intent was to identify unrecognized central nervous system (CNS) injury that..
Read MoreEarly colonoscopy for detection of colon ischemia after extracorporeal cardiopulmonary resuscitation
Abstract Dear Editor, Extracorporeal cardiopulmonary resuscitation (ECPR) refers to the initiation of venoarterial extracorporeal membrane oxygenation (VA ECMO) during cardiac arrest to restore systemic perfusion with oxygenated blood []. Prolonged..
Read MoreAbstract Cerebrovascular autoregulation maintains stable cerebral blood flow by counteracting slow changes in cerebral perfusion pressure (termed “slow waves”). Conventional assessment involves invasive techniques using intracranial pressure (ICP) or technically..
Read MoreAbstract Background We have demonstrated cardioprotection by the adenosine triphosphate–sensitive potassium (KATP) channel opener diazoxide in multiple animal models in an effort to reduce myocardial stunning following cardiac surgery. These..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized for life-threatening cardiac and/or respiratory failure refractory to conventional treatment. Acute kidney injury (AKI) and fluid balance disorders commonly occur both..
Read MoreAbstract Background: Sanguineous preparation of the cardiopulmonary bypass (CPB) circuit with allogeneic blood products is known to contain substantial complement mediator burden. This study aims to assess the longitudinal immunologic impacts..
Read MoreAbstract Background Despite advances in cardiopulmonary resuscitation (CPR), survival after out-of-hospital cardiac arrest (OHCA) remains low. Use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) as extracorporeal CPR (ECPR) may improve..
Read MoreAbstract The role of intra-aortic balloon pump (IABP) use in optimizing patients for durable left ventricular assist device (LVAD) implantation is being reevaluated in the era of modern centrifugal, magnetically..
Read MoreAbstract Objectives Postcardiopulmonary bypass bleeding is frequent and distinctive because of its associated coagulopathy. Despite diagnostic and therapeutic progress, substantial variability persists in hemostatic transfusion practices. Because transfusion of hemostatic..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) provides lifesaving support for patients with cardiopulmonary failure but poses complex ethical challenges that may generate moral distress for clinicians, patients, and families. We convened..
Read MoreAbstract Importance Acute respiratory distress syndrome (ARDS) represents a frequent and serious complication after cardiovascular surgery. Although sivelestat, a specific neutrophil elastase inhibitor, has demonstrated therapeutic potential in preliminary studies, the..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is widely used in patients with severe cardiac or respiratory failure. ECMO is resource and cost intensive and carries the potential for significant complications; therefore,..
Read MoreSerum lactate is a critical biomarker in cardiac surgery, offering insights into tissue oxygenation and metabolic status. Elevated lactate levels during cardiopulmonary bypass (CPB) can indicate inadequate perfusion, hypoxia, or..
Read MoreAbstract Introduction Survival after out-of-hospital cardiac arrest (OHCA) remains poor, particularly for refractory ventricular fibrillation/ventricular tachycardia (VF/VT). Extracorporeal cardiopulmonary resuscitation (ECPR) improves outcomes when delivered within 60 minutes of low-flow..
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