Pediatric

Perfusfind S.L.

Abstract In children, validated tools to monitor anaesthetic depth are lacking. In routine practice, dosing of volatile agents relies on surrogate markers such as minimum alveolar concentration and autonomic responses. In noncardiac surgery, sevoflurane administration is typically guided by its end tidal concentration (FeSevo), which closely reflects cerebral partial pressure and..

Perfusfind S.L.

Abstract Background Pediatric patients undergoing cardiac surgery are at risk for developing positive cumulative fluid balance (CFB). Our goal was to study postoperative CFB in this population, its explanatory variables, and its effect on clinical outcomes during pediatric intensive care unit (PICU) stay and follow-up. Methods Retrospective single center study..

Perfusfind S.L.

Abstract Objectives To determine whether individualized heparin dosing guided by a heparin dose-response (HDR) curve is noninferior to conventional weight-based dosing in achieving target activated clotting time (ACT) of ≥480 seconds before cardiopulmonary bypass (CPB) and to compare total heparin and protamine requirements, postoperative blood loss, and transfusion needs in..

Perfusfind S.L.

Abstract Background Children undergoing high-risk cardiac surgery face significant postoperative morbidity and mortality risk, and early recognition of impaired systemic perfusion is critical. Current monitoring modalities, such as lactate, central venous oxygen saturation, and near-infrared spectroscopy, are indirect surrogates of cardiac output and are either invasive or have limited predictive..

Perfusfind S.L.

Abstract Objectives Antegrade cerebral perfusion (ACP) is used to protect the brain during aortic arch reconstructions. It is unknown whether cerebral autoregulation remains intact during ACP. This study was designed to determine whether neonates exhibit cerebral vasoreactivity during ACP. Design Retrospective cohort study. Setting Single-center, university hospital. Patients Neonates undergoing..

Perfusfind S.L.

Abstract Background: Establishing the Korean Pediatric and Congenital Heart Surgery Database (KPCHSD) and linking it to the World Database for Pediatric and Congenital Heart Surgery (WDPCHS) is an important step toward creating a global network for quality care. Worldwide outcomes data are needed to support quality assurance and advocacy for..

Perfusfind S.L.

Abstract Objectives Inadequate heparin response is frequently observed in neonates and young infants. While low antithrombin level is considered to be the primary cause, the existing literature suggests that it is not necessarily responsible. However, granular coagulation factor profiling data are rather limited. Design Prospective, single-center study. Setting Tertiary academic..

Perfusfind S.L.

Abstract Objectives To determine the prevalence of iron deficiency and iron deficiency anemia and their association with adverse outcomes in children undergoing cardiac surgery with cardiopulmonary bypass. Design Retrospective review. Setting Single-center, academic quaternary children’s hospital. Participants Eight hundred eighty-six cardiac surgery patients aged 0 to 18 years at the..

Perfusfind S.L.

Abstract Objectives: Pediatric in-hospital cardiac arrest (IHCA) events leading to extracorporeal cardiopulmonary resuscitation (E-CPR) most often occur in the ICU in cardiac patients. Since there is little information about using E-CPR for pediatric IHCA in the emergency department (ED), we aimed to describe this population. Design: The American Heart Association’s..

Perfusfind S.L.

Abstract Background Infants with congenital diaphragmatic hernia (CDH) are at increased risk of neuroimaging abnormalities and neurodevelopmental impairment. There is no standardized neuroimaging scoring system in this patient population. Our objective was to develop a novel Neonatal Brain Injury Score (NBIS) and evaluate its association with neurodevelopmental outcomes. Methods We..