Pediatric

Perfusfind S.L.

LVAD Implantation in Pediatric Population inflow from LV and outflow to Ascending Aorta.   LVAD Implantation in the Pediatric Population   By Sam Zeraatiannejaddavani, MD   ⸻   A — Assessment & Indications   1. Clinical Indications •Refractory Stage D heart failure despite optimal medical therapy (NYHA IV / INTERMACS..

Perfusfind S.L.

Abstract Background Children with heart disease and cardiopulmonary failure may be supported with extracorporeal membrane oxygenation (ECMO) for stabilization before cardiac surgery. This study describes their epidemiology and outcomes. Methods The Society of Thoracic Surgeons Congenital Heart Surgery Database was queried for patients aged <18 years who underwent ECMO cannulation..

Perfusfind S.L.

Abstract Objectives:  To derive and externally validate supervised machine learning (ML) models predictive of cardiac surgery-associated acute kidney injury (CS-AKI). Design:  Retrospective cohort analysis. Setting:  Multicenter (4), cardiac surgical centers from January 2019 to February 2022. Patients:  Seven days to 18 years old who had undergone cardiac surgery. Interventions:  None...

Perfusfind S.L.

Abstract Objectives To compare the effects of total intravenous anesthesia (TIVA) versus volatile anesthesia on systemic inflammation and early postoperative cognitive recovery in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass. Design Prospective, randomized controlled trial. Setting A tertiary care center specializing in pediatric cardiac surgery. Participants Fifty children aged..

Perfusfind S.L.

Abstract Introduction: The use of cardiopulmonary bypass (CPB) is necessary during the repair of most congenital heart disease (CHD). The surface area of the CPB circuit and the volume of the filling prime are relatively large concerning the volume of neonatal and pediatric patients. Consequently, blood is often required to..

Perfusfind S.L.

Abstract Background Platelet transfusions are frequently given to preterm neonates. However, observational and randomized studies have reported higher morbidity and mortality associated with increased numbers of transfusions. We hypothesized that this was related to pro-inflammatory effects of transfused platelets. This study assessed the effects of platelet transfusions on bleeding, plasma..

Perfusfind S.L.

Abstract Background Cardiopulmonary bypass (CPB) plays a crucial role in cardiac surgery, with the pump being a key component affecting both hemolysis and thrombosis. Centrifugal levitating pumps (CP) have demonstrated superiority over roller pumps due to reduced hemolysis, but thrombotic risk remains a concern. Nonetheless, there exists a technological gap..

Perfusfind S.L.

Abstract Introduction Heparin is usually added to infant cardiopulmonary bypass circuit primes. Ultrafiltration is often used to minimise prime volume before commencing bypass. The extent of heparin removal from bypass primes by ultrafiltration is unknown, however at our institution it was assumed that heparin is freely filtered. The primary aim..

Perfusfind S.L.

Abstract Objective This scoping review aimed to examine current literature on the use of point-of-care ultrasound (POCUS) in paediatric patients supported by extracorporeal membrane oxygenation (ECMO). It assessed existing evidence, summarised key findings, explored theoretical limitations, and identified knowledge gaps. Methods A comprehensive search of Medline, CINAHL, Embase, and the..

Perfusfind S.L.

Abstract Background:  Infants with congenital heart disease (CHD) frequently undergo surgery during their first year of life. Infants undergoing CHD surgery experience systemic inflammation and haemodilution that can deplete circulating immunoglobulins (Ig). Methods:  In this prospective single-centre observational cohort study without healthy controls, we quantified IgG, IgA and IgM at..