Monthly Archives: abril 2026

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ASSISTENZA EXTRACORPOREA MEDIANTE ECMO IN TERAPIA INTENSIVA ED EMERGENZA - 4/5 Giugno

  Il supporto extracorporeo mediante ECMO (Extracorporeal Membrane Oxygenation, ECMO) rappresenta oggi una delle frontiere più complesse e decisive della terapia intensiva, poiché è in grado di fornire un temporaneo..

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Train the Trainers ECMO - 15/17 July

Train the Trainers ECMO European edition: the course to prepare ECMO educators to design, deliver, and evaluate high-quality, simulation-based training in accordance with ELSO educational standards, combining sound instructional design,..

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Cybersecurity as it relates to perfusion

Abstract Perfusionists must maintain strong digital security habits, know the inherent risks of devices in use, and have a healthy respect for the consequences of a security breach at a..

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Real-Time Individualization of UFH Dosing in Cardiac Procedures: Development and Validation of an Online ACT-Based Target-Controlled Tool

Abstract Objectives To develop and validate, a real-time algorithm to individualize unfractionated heparin (UFH) dosing based on activated clotting time (ACT) dynamics in cardiac procedures with or without cardiopulmonary bypass..

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Use of plasmapheresis during cardiopulmonary bypass in a pediatric heart transplant of a patient with Failing Fontan Physiology: first case…

Abstract Background: A 17-year-old male patient diagnosed with a single ventricle, in a failed Fontan stage, was evaluated prior to heart transplantation. The patient had a panel-reactive antibody (PRA) for..

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Comparison of Membrane Lung Function at Different Altitudes: A Prospective Two-Center Study in Xining and Beijing

Abstract Background The use of extracorporeal membrane oxygenation (ECMO) has expanded significantly, especially during the COVID-19 pandemic, but membrane lung (ML) function at high altitudes remains unexplored. This study aimed..

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Clinical correlates for major bleeding during veno-arterial extracorporeal membrane oxygenation support: a time-dependent perspective

Abstract Background Major bleeding is a common and serious complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO). Current perspectives on bleeding risk fail to reflect dynamic changes over time in..

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Continuous vs pulsatile arterial cannula flow for venoarterial extracorporeal membrane oxygenation: A multiscale computational fluid dynamics analysis

Abstract Background and Objective Venoarterial extracorporeal membrane oxygenation (VA ECMO) circuits typically utilise a continuous flow (CF) of blood to support patients suffering from refractory cardiorespiratory dysfunction. Pulsatile flow (PF)..

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Elevated phthalate exposure and metabolic susceptibility increased breast cancer risk: A 20-y follow-up study in Taiwan

Abstract Widely used phthalates, especially di-(2-ethylhexyl) phthalate (DEHP), increase breast cancer risk in experimental animals and humans, but long-term follow-up evidence of its human breast carcinogenicity remains inconclusive. This nested..

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Integration of Anesthesia and Perfusion Variables into Europe’s Largest Congenital Cardiac Surgery Outcomes Database: Methods and First List of Candidate…

Abstract Objectives Numerous databases exist in the field of cardiac surgery across Europe, but none of them combine the entire captured data of all clinical specialties involved in the care..

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Semi-Empirical Model to Predict Blood Flow in an Extracorporeal Respiratory Support Circuit Driven by Ventricular Assist Devices

Abstract Despite increasing clinical interest in ambulatory extracorporeal membrane oxygenation (ECMO), its equipment is not optimally designed for portability. Blood pumps are too heavy for ambulation, as the lightest system..

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Acid–Base Status During Venoarterial Extracorporeal Membrane Oxygenator Support in Patients With Cardiogenic Shock

Abstract Background The prognostic significance of an adverse acid–base milieu despite venoarterial extracorporeal membrane oxygenation support in patients with cardiogenic shock remains poorly defined. We examined metabolic and respiratory disturbances..

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Beyond goal directed perfusion: Individualizing O2-delivery to O2-consumption

Abstract Goal directed perfusion (GDP) aims to maintain an O2 delivery above 270-300 ml/min/m2, during cardiopulmonary bypass. This strategy decreases the incidence of postoperative acute kidney injury. We first developed a simple..

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Interdisciplinary and Cross-Sectoral Perioperative Care Model in Cardiac Surgery: ERAS Implementation in the Setting of Minimally Invasive Heart Valve Surgery…

Abstract Objectives Enhanced recovery after surgery (ERAS) protocols are patient-centred, interprofessional perioperative care models aimed at reducing hospital stays, complications, healthcare costs, and improving patient satisfaction. Evidence for ERAS in..

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Extracorporeal Cardiopulmonary Resuscitation in Adult Patients Following In-Hospital and Out-of-Hospital Refractory Cardiac Arrest: A Narrative Review

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) involves cannulation and initiation of venoarterial extracorporeal membrane oxygenation, offering enhanced perfusion during refractory cardiac arrest when conventional cardiopulmonary resuscitation fails. The use of ECPR..

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Impact of early hyperoxia on outcomes during neonatal and pediatric veno-arterial extracorporeal life support

Abstract Background: Hyperoxia induces oxidative stress and can exacerbate inflammatory response to Veno-Arterial Extracorporeal Life Support (VA–ECLS). This study aimed to evaluate the association between hyperoxia during VA–ECLS and morbidity, complications,..

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Nanoconjugated anticoagulant coating with blood repellency for extracorporeal circulation in cardiothoracic surgery

Abstract Coating strategies play a pivotal role in anticoagulation management during extracorporeal circulation. While heparin-based coatings remain the most widely used, their limited anticoagulant efficacy may lead to adverse events..

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A bedside staffing model with perfusionists for pediatric extracorporeal membrane oxygenation (ECMO) at a high-volume center

Abstract Background: Extracorporeal membrane oxygenation (ECMO) in pediatric patients requires monitoring by specialists to optimize outcomes. Practice variability exists among pediatric ECMO centers across the country. We present a bedside..

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Hyperlipidemia and Postoperative Hallucinations After Cardiac Surgery: Insights from the VAACS Cohort Study

Abstract Objective To evaluate the cumulative incidence and predictors of postoperative visual and auditory hallucinations among hyperlipidemic and normolipidemic patients undergoing cardiac surgery, with a particular focus on lipid indices,..

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Machine learning for the prediction of acute kidney injury post cardiac surgery: a systematic review and meta-analysis

Abstract Background and objectives Cardiac surgery associated acute kidney injury can lead to increased morbidity, mortality, and hospitalization. The available risk assessment tools have limited predictive ability. Machine learning has..

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Outcomes of Adult Patients With Acute Liver Dysfunction and Chronic Liver Disease Supported by Extracorporeal Membrane Oxygenation

Abstract The impact of acute liver dysfunction and chronic liver disease on adult patients receiving extracorporeal membrane oxygenation (ECMO) support remains unclear. To investigate this, we performed a retrospective analysis..

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Standardization of In Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development

Abstract Extracorporeal life support (ECLS) technology has witnessed remarkable advancements during the last decades. However, further research and development of devices are required to increase, for example, performance-efficiency, hemocompatibility, and..

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Hypoperfusion and cardiac surgery-associated major adverse kidney events: a single-center retrospective cohort study

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious complication, significantly increasing postoperative morbidity and mortality. We aimed to evaluate whether intraoperative peripheral perfusion index (PPI)..

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Evaluating the Impact of a Standardized Protocol for Managing Refractory Vasoplegia After Cardiopulmonary Bypass

Abstract Objectives This study aimed to evaluate the hemodynamic impact and cost-effectiveness of a standardized protocol for refractory vasoplegia occurring after cardiopulmonary bypass (CPB). Design Observational, pre-post study. Setting A..

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Pulmonary Endarterectomy (PEA)

    Perfusion Management – Technical Notes   Core Perfusion Strategy   •Full CPB with bicaval cannulation •Target DHCA at 18–20°C •Ensure excellent venous drainage •Maintain uniform cooling (ΔT <10°C)..

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Redo Aorta to Pulmonary Fistula and Femoral Cannulation

    Technical Challenges & Surgical Strategy Background •Aorto–pulmonary fistula is a rare but life-threatening complication •Common in redo cardiac surgery •Frequently associated with: •Prior aortic valve/root procedures •Infective endocarditis..

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Anesthetic Perspective on Total Arch Replacement With Frozen Elephant Trunk Surgery

Abstract The total arch replacement with frozen elephant trunk (TARFET) technique has emerged as a leading treatment for extensive aortic pathologies that span from the aortic arch to the proximal..

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Delta perfusion rate predicts the development of adverse outcome in cardiopulmonary bypass patients

Abstract Introduction: Despite the advances in CPB, various complications may occur. Prediction and anticipation of these undesirable outcomes is of great importance. For this reason, various markers have been tried to..

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Generalizability of Landmark Temporary MCS Device Trials: Insights From the CSWG Registry

Abstract Background Landmark randomized controlled trials like DanGer Shock, IABP-SHOCK II, and ECLS-SHOCK guide infarct-related cardiogenic shock (CS) management with temporary mechanical circulatory support (tMCS), but strict enrollment criteria may..

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Bivalirudin Monitoring Using Dilute Thrombin Time in Pediatric Extracorporeal Membrane Oxygenation: Single-Center, Retrospective Cost Analysis, 2018–2023

Abstract Objectives:  The parenteral anticoagulant bivalirudin has favorable safety and efficacy outcomes compared with unfractionated heparin (UFH) in pediatric patients requiring extracorporeal membrane oxygenation (ECMO), and is frequently monitored using..

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