Il supporto extracorporeo mediante ECMO (Extracorporeal Membrane Oxygenation, ECMO) rappresenta oggi una delle frontiere più complesse e decisive della terapia intensiva, poiché è in grado di fornire un temporaneo..
Read MoreTrain the Trainers ECMO European edition: the course to prepare ECMO educators to design, deliver, and evaluate high-quality, simulation-based training in accordance with ELSO educational standards, combining sound instructional design,..
Read MoreAbstract Perfusionists must maintain strong digital security habits, know the inherent risks of devices in use, and have a healthy respect for the consequences of a security breach at a..
Read MoreAbstract Objectives To develop and validate, a real-time algorithm to individualize unfractionated heparin (UFH) dosing based on activated clotting time (ACT) dynamics in cardiac procedures with or without cardiopulmonary bypass..
Read MoreAbstract Background: A 17-year-old male patient diagnosed with a single ventricle, in a failed Fontan stage, was evaluated prior to heart transplantation. The patient had a panel-reactive antibody (PRA) for..
Read MoreAbstract Background The use of extracorporeal membrane oxygenation (ECMO) has expanded significantly, especially during the COVID-19 pandemic, but membrane lung (ML) function at high altitudes remains unexplored. This study aimed..
Read MoreAbstract Background Major bleeding is a common and serious complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO). Current perspectives on bleeding risk fail to reflect dynamic changes over time in..
Read MoreAbstract Background and Objective Venoarterial extracorporeal membrane oxygenation (VA ECMO) circuits typically utilise a continuous flow (CF) of blood to support patients suffering from refractory cardiorespiratory dysfunction. Pulsatile flow (PF)..
Read MoreAbstract Widely used phthalates, especially di-(2-ethylhexyl) phthalate (DEHP), increase breast cancer risk in experimental animals and humans, but long-term follow-up evidence of its human breast carcinogenicity remains inconclusive. This nested..
Read MoreAbstract Objectives Numerous databases exist in the field of cardiac surgery across Europe, but none of them combine the entire captured data of all clinical specialties involved in the care..
Read MoreAbstract Despite increasing clinical interest in ambulatory extracorporeal membrane oxygenation (ECMO), its equipment is not optimally designed for portability. Blood pumps are too heavy for ambulation, as the lightest system..
Read MoreAbstract Background The prognostic significance of an adverse acid–base milieu despite venoarterial extracorporeal membrane oxygenation support in patients with cardiogenic shock remains poorly defined. We examined metabolic and respiratory disturbances..
Read MoreAbstract Goal directed perfusion (GDP) aims to maintain an O2 delivery above 270-300 ml/min/m2, during cardiopulmonary bypass. This strategy decreases the incidence of postoperative acute kidney injury. We first developed a simple..
Read MoreAbstract Objectives Enhanced recovery after surgery (ERAS) protocols are patient-centred, interprofessional perioperative care models aimed at reducing hospital stays, complications, healthcare costs, and improving patient satisfaction. Evidence for ERAS in..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (ECPR) involves cannulation and initiation of venoarterial extracorporeal membrane oxygenation, offering enhanced perfusion during refractory cardiac arrest when conventional cardiopulmonary resuscitation fails. The use of ECPR..
Read MoreAbstract Background: Hyperoxia induces oxidative stress and can exacerbate inflammatory response to Veno-Arterial Extracorporeal Life Support (VA–ECLS). This study aimed to evaluate the association between hyperoxia during VA–ECLS and morbidity, complications,..
Read MoreAbstract Coating strategies play a pivotal role in anticoagulation management during extracorporeal circulation. While heparin-based coatings remain the most widely used, their limited anticoagulant efficacy may lead to adverse events..
Read MoreAbstract Background: Extracorporeal membrane oxygenation (ECMO) in pediatric patients requires monitoring by specialists to optimize outcomes. Practice variability exists among pediatric ECMO centers across the country. We present a bedside..
Read MoreAbstract Objective To evaluate the cumulative incidence and predictors of postoperative visual and auditory hallucinations among hyperlipidemic and normolipidemic patients undergoing cardiac surgery, with a particular focus on lipid indices,..
Read MoreAbstract Background and objectives Cardiac surgery associated acute kidney injury can lead to increased morbidity, mortality, and hospitalization. The available risk assessment tools have limited predictive ability. Machine learning has..
Read MoreAbstract The impact of acute liver dysfunction and chronic liver disease on adult patients receiving extracorporeal membrane oxygenation (ECMO) support remains unclear. To investigate this, we performed a retrospective analysis..
Read MoreAbstract Extracorporeal life support (ECLS) technology has witnessed remarkable advancements during the last decades. However, further research and development of devices are required to increase, for example, performance-efficiency, hemocompatibility, and..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious complication, significantly increasing postoperative morbidity and mortality. We aimed to evaluate whether intraoperative peripheral perfusion index (PPI)..
Read MoreAbstract Objectives This study aimed to evaluate the hemodynamic impact and cost-effectiveness of a standardized protocol for refractory vasoplegia occurring after cardiopulmonary bypass (CPB). Design Observational, pre-post study. Setting A..
Read MorePerfusion Management – Technical Notes Core Perfusion Strategy •Full CPB with bicaval cannulation •Target DHCA at 18–20°C •Ensure excellent venous drainage •Maintain uniform cooling (ΔT <10°C)..
Read MoreTechnical Challenges & Surgical Strategy Background •Aorto–pulmonary fistula is a rare but life-threatening complication •Common in redo cardiac surgery •Frequently associated with: •Prior aortic valve/root procedures •Infective endocarditis..
Read MoreAbstract The total arch replacement with frozen elephant trunk (TARFET) technique has emerged as a leading treatment for extensive aortic pathologies that span from the aortic arch to the proximal..
Read MoreAbstract Introduction: Despite the advances in CPB, various complications may occur. Prediction and anticipation of these undesirable outcomes is of great importance. For this reason, various markers have been tried to..
Read MoreAbstract Background Landmark randomized controlled trials like DanGer Shock, IABP-SHOCK II, and ECLS-SHOCK guide infarct-related cardiogenic shock (CS) management with temporary mechanical circulatory support (tMCS), but strict enrollment criteria may..
Read MoreAbstract Objectives: The parenteral anticoagulant bivalirudin has favorable safety and efficacy outcomes compared with unfractionated heparin (UFH) in pediatric patients requiring extracorporeal membrane oxygenation (ECMO), and is frequently monitored using..
Read More





















