December 2025 - Perfusfind Intensive Care

Measurement and interpretation of central venous pressure: a narrative review

Summary This narrative review explores the historical development, physiological underpinnings, measurement techniques, and clinical relevance of central venous pressure (CVP) in perioperative and critical care settings. Although traditionally used as a marker for fluid responsiveness and intravascular volume status, evidence now emphasizes that CVP alone is unreliable for guiding fluid therapy. Nonetheless, when used alongside […]

central venous pressure

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Respiratory

Can we predict the future of respiratory failure prediction?

Summary This article examines current methods of predicting respiratory failure, emphasizing existing scoring systems, biomarkers, and their limitations. It introduces machine learning (ML) as a promising alternative for predicting acute respiratory failure and reviews key challenges to integrating ML into clinical practice. The authors advocate for rigorous validation, thoughtful trial design, and clinician collaboration to

Respiratory Failure

Can we predict the future of respiratory failure prediction? Read Post »

Mechanical Ventilation

Automated mechanical ventilator design and analysis using neural network

Summary This study describes the design, simulation, and validation of an automated mechanical ventilator system using neural networks to optimize critical ventilation parameters. The ventilator specifically addresses clinical conditions such as pneumonia and chronic obstructive pulmonary disease (COPD). By employing feed-forward neural networks (FFNN) to regulate parameters like tidal volume, respiratory rate, and inspiration-to-expiration (I:E)

mechanical ventilation, ventilation parameters

Automated mechanical ventilator design and analysis using neural network Read Post »