Microcirculation

Cardiovascular

Cardiogenic shock syndrome unraveled: understanding the different layers of heterogeneity

Summary Cardiogenic shock (CS) represents a heterogeneous clinical syndrome characterized by sustained tissue hypoperfusion due to cardiac dysfunction, encompassing diverse etiological, hemodynamic, and molecular profiles. The paper emphasizes the need for recognizing CS heterogeneity through clinical classification, ventriculo-arterial coupling, macro- and microcirculatory considerations, and molecular subphenotyping. These multiple layers of complexity suggest that personalized medicine […]

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Sepsis

Microcirculation: Current Perspective in Diagnostics, Imaging, and Clinical Applications

Abstract This review discusses the pivotal role of microcirculation in maintaining tissue oxygenation and waste removal and highlights its significance in various pathological conditions. It delves into the cellular mechanisms underlying hemodynamic coherence, elucidating the roles of the endothelium, glycocalyx, and erythrocytes in sustaining microcirculatory integrity. Furthermore, the review gives comprehensive information about microcirculatory changes

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