December 2024

Circulatory

Post-resuscitation shock: recent advances in pathophysiology and treatment

Abstract A post-resuscitation shock occurs in 50–70% of patients who had a cardiac arrest. It is an early and transient complication of the post-resuscitation phase, which frequently leads to multiple-organ failure and high mortality. The pathophysiology of post-resuscitation shock is complex and results from the whole-body ischemia–reperfusion process provoked by the sequence of circulatory arrest, […]

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Circulatory, Mechanical Ventilation, Pharmacological Insights in Critical Care

Ventilation and Oxygenation During and After Adult Cardiopulmonary Resuscitation: Changing Paradigms

Abstract Cardiac arrest (CA) remains a major cause of death despite advancements in cardiopulmonary resuscitation (CPR), post-resuscitation care, and international efforts to develop evidence-based guidelines. Effectively managing ventilation and oxygenation during and after CPR is vital for patient survival and neurological outcomes, yet it remains a challenging task. This review examines current strategies for ventilation

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Mechanical Ventilation

“Awake” Cannulation of Patients for Venovenous Extracorporeal Membrane Oxygen: An Analysis of the Extracorporeal Life Support Organization Registry

Abstract IMPORTANCE: “Awake” cannulation for venovenous extracorporeal membrane oxygenation (ECMO), where patients remain spontaneously breathing without invasive mechanical ventilation during the cannulation procedure, may reduce lung injury from positive pressure ventilation and promote patient mobility. OBJECTIVES: To examine the association between “awake” cannulation for venovenous ECMO and patient outcomes. DESIGN, SETTING, AND PARTICIPANTS: Analysis of

“Awake” Cannulation of Patients for Venovenous Extracorporeal Membrane Oxygen: An Analysis of the Extracorporeal Life Support Organization Registry Read Post »

Respiratory

The Ventilatory Ratio as a Predictor of Successful Weaning from a Veno-Venous Extracorporeal Membrane Oxygenator

Abstract Background: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a critical intervention for patients with severe lung failure, especially acute respiratory distress syndrome (ARDS). The weaning process from ECMO relies largely on expert opinion due to a lack of evidence-based guidelines. The ventilatory ratio (VR), which correlates with dead space and mortality in ARDS, is calculated

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Miscellaneous

Clinical governance in intensive care medicine

Patient safety has become a primary focus for healthcare improvement, particularly in intensive care units (ICUs) where the complexity increases the risk of medical errors compared to other hospital settings [1]. Therefore, ensuring safe care is crucial and should be actively pursued as a fundamental value [2]. Clinical governance (CG) is how healthcare organizations (including

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Respiratory

Distinct phenotype and risk factor analysis of persistent airflow limitation among asthmatic children: a case-control study

Abstract Background Persistent airflow limitation (PAL) in childhood asthma is associated with a poor prognosis. The aim of this study was to categorize asthmatic children with PAL into distinct phenotypes and investigate the risk factors associated with each phenotype. Methods We conducted a case-control study with a total of 119 PAL patients and 120 non-PAL

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Distinct phenotype and risk factor analysis of persistent airflow limitation among asthmatic children: a case-control study Read Post »

Mechanical Ventilation, Pharmacological Insights in Critical Care

Pressure support, patient effort and tidal volume: a conceptual model for a non linear interaction

Abstract Pressure support ventilation (PSV) is a form of assisted ventilation which has become frequently used, with the aim of partially unloading the patient’s inspiratory muscles. Both under- and over-assistance should be avoided to target a lung- and diaphragm- protective ventilation. Herein, we propose a conceptual model, supported by actual data, to describe how patient

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Circulatory

Post-Cardiac Arrest Care in Extracorporeal Cardiopulmonary Resuscitation

Abstract   OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) serves as a lifesaving intervention for patients experiencing refractory cardiac arrest. With its expanding usage, there’s a burgeoning focus on improving patient outcomes through optimal management in the acute phase after cannulation. This review explores systematic post-cardiac arrest management strategies, associated complications, and prognostication in ECPR patients. DATA

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Sepsis

Epidemiology of β-blocker use among critically iII patients during and after septic shock

Abstract   Introduction β-Blockers are used widely in the outpatient care of chronic disease, but less is known about how to restart chronic therapy during and after hospitalization for septic shock [1, 2]. We sought to characterize the epidemiology of β-blocker treatment during and after septic shock among patients administered chronic β-blocker therapy in the year

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Epidemiology of β-blocker use among critically iII patients during and after septic shock Read Post »

Circulatory

Blood Pressure Management for Hypotensive Patients in Intensive Care and Perioperative Cardiovascular Settings

Abstract Blood pressure is a critical physiological parameter, particularly in the context of cardiac intensive care and perioperative settings. As a primary indicator of organ perfusion, the maintenance of adequate blood pressure is imperative for the assurance of sufficient tissue oxygen delivery. Among critically ill and major surgery patients, the continuous monitoring of blood pressure

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