October 2025

Mechanical Ventilation, Respiratory

Revisiting Acute Respiratory Distress Syndrome ventilation management: Time for a paradigm shift focusing on tidal volume

Abstract: Merola and colleagues critically evaluate current Acute Respiratory Distress Syndrome (ARDS) ventilation strategies, emphasizing limitations inherent in universally applying low tidal volume (VT) strategies. They argue for personalized, physiology-driven ventilation approaches that incorporate mechanical power, compliance, and transpulmonary pressures. The authors highlight the complexity and heterogeneity of ARDS, suggesting the inadequacy of global parameters […]

, , , ,

Revisiting Acute Respiratory Distress Syndrome ventilation management: Time for a paradigm shift focusing on tidal volume Read Post »

Respiratory

Physical and respiratory therapy in the critically ill patient with obesity: a narrative review

Abstract: Martínez-Camacho et al. discuss the critical aspects of physical and respiratory therapy for obese patients in the ICU, highlighting the complexities of obesity-related respiratory and metabolic disturbances. They emphasize the importance of early mobilization, meticulous ventilatory management, personalized nutritional support, and multidisciplinary collaboration as pivotal strategies to enhance functional outcomes and reduce complications in

, ,

Physical and respiratory therapy in the critically ill patient with obesity: a narrative review Read Post »

Neurology

Managing Intracranial Pressure Crisis

Abstract: Viarasilpa provides a comprehensive review of current strategies for managing intracranial pressure (ICP) crises, emphasizing critical care management, ICP monitoring, neuromonitoring, and evidence-based therapeutic approaches. The review integrates protocols from the Brain Trauma Foundation (BTF), Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC), and Consensus-based management protocol (CREVICE), advocating personalized, neuromonitoring-driven interventions to

, , ,

Managing Intracranial Pressure Crisis Read Post »

Cardiovascular

Management of cardiogenic shock: state-of-the-art

Abstract: Jung et al. provide a comprehensive review addressing current knowledge and contemporary practices in the management of cardiogenic shock (CS). Despite advancements, mortality remains high, and the complexity of patient care underscores the need for individualized treatments. The authors highlight recent evidence in pharmacological therapies, mechanical circulatory support (MCS), and the potential for personalized

,

Management of cardiogenic shock: state-of-the-art Read Post »

Sepsis

Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised…

Abstract: Endo et al. conducted the OPTPRESS trial, a multicenter randomized controlled trial in Japan, evaluating whether a higher mean arterial pressure (MAP) target (80–85 mmHg) reduces mortality in older patients (≥65 years) with septic shock compared to standard targets (65–70 mmHg). The trial was terminated early due to increased mortality and adverse events in

, ,

Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised… Read Post »

Cardiovascular

Intraoperative extracorporeal support for lung transplant: a systematic review and network meta-analysis

Abstract: Pettenuzzo et al. conducted a systematic review and network meta-analysis evaluating the efficacy and safety of intraoperative extracorporeal supports—veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and cardiopulmonary bypass (CPB)—compared to off-pump strategies during lung transplantation (LT). Their analysis revealed that off-pump approaches generally offered better outcomes, while V-A ECMO, particularly as a default strategy, showed

, ,

Intraoperative extracorporeal support for lung transplant: a systematic review and network meta-analysis Read Post »

Pulmonary

Pulmonary shunt in critical care: a practical approach with clinical scenarios

Abstract: Raimondi Cominesi et al. deliver an extensive review on pulmonary shunt, a critical physiological phenomenon where venous blood bypasses alveolar gas exchange, leading to impaired oxygenation. The authors provide practical methods to assess and calculate pulmonary shunt in various critical care scenarios, highlighting its clinical importance, especially in complex conditions such as acute respiratory

,

Pulmonary shunt in critical care: a practical approach with clinical scenarios Read Post »

Scroll to Top