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Miscellaneous

Clinical governance in intensive care medicine

Patient safety has become a primary focus for healthcare improvement, particularly in intensive care units (ICUs) where the complexity increases the risk of medical errors compared to other hospital settings [1]. Therefore, ensuring safe care is crucial and should be actively pursued as a fundamental value [2]. Clinical governance (CG) is how healthcare organizations (including […]

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Respiratory

Distinct phenotype and risk factor analysis of persistent airflow limitation among asthmatic children: a case-control study

Abstract Background Persistent airflow limitation (PAL) in childhood asthma is associated with a poor prognosis. The aim of this study was to categorize asthmatic children with PAL into distinct phenotypes and investigate the risk factors associated with each phenotype. Methods We conducted a case-control study with a total of 119 PAL patients and 120 non-PAL

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Distinct phenotype and risk factor analysis of persistent airflow limitation among asthmatic children: a case-control study Read Post »

Mechanical Ventilation, Pharmacological Insights in Critical Care

Pressure support, patient effort and tidal volume: a conceptual model for a non linear interaction

Abstract Pressure support ventilation (PSV) is a form of assisted ventilation which has become frequently used, with the aim of partially unloading the patient’s inspiratory muscles. Both under- and over-assistance should be avoided to target a lung- and diaphragm- protective ventilation. Herein, we propose a conceptual model, supported by actual data, to describe how patient

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Pressure support, patient effort and tidal volume: a conceptual model for a non linear interaction Read Post »

Circulatory

Post-Cardiac Arrest Care in Extracorporeal Cardiopulmonary Resuscitation

Abstract   OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) serves as a lifesaving intervention for patients experiencing refractory cardiac arrest. With its expanding usage, there’s a burgeoning focus on improving patient outcomes through optimal management in the acute phase after cannulation. This review explores systematic post-cardiac arrest management strategies, associated complications, and prognostication in ECPR patients. DATA

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Sepsis

Epidemiology of β-blocker use among critically iII patients during and after septic shock

Abstract   Introduction β-Blockers are used widely in the outpatient care of chronic disease, but less is known about how to restart chronic therapy during and after hospitalization for septic shock [1, 2]. We sought to characterize the epidemiology of β-blocker treatment during and after septic shock among patients administered chronic β-blocker therapy in the year

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Epidemiology of β-blocker use among critically iII patients during and after septic shock Read Post »

Circulatory

Blood Pressure Management for Hypotensive Patients in Intensive Care and Perioperative Cardiovascular Settings

Abstract Blood pressure is a critical physiological parameter, particularly in the context of cardiac intensive care and perioperative settings. As a primary indicator of organ perfusion, the maintenance of adequate blood pressure is imperative for the assurance of sufficient tissue oxygen delivery. Among critically ill and major surgery patients, the continuous monitoring of blood pressure

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Neurology

Post-Traumatic Cerebral Infarction: A Narrative Review of Pathophysiology, Diagnosis, and Treatment

Abstract Traumatic brain injury (TBI) is a common diagnosis requiring acute hospitalization. Long-term, TBI is a significant source of health and socioeconomic impact in the United States and globally. The goal of clinicians who manage TBI is to prevent secondary brain injury. In this population, post-traumatic cerebral infarction (PTCI) acutely after TBI is an important

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Post-Traumatic Cerebral Infarction: A Narrative Review of Pathophysiology, Diagnosis, and Treatment Read Post »

Circulatory

Cardiogenic shock

Summary Cardiogenic shock is a complex syndrome defined by systemic hypoperfusion and inadequate cardiac output arising from a wide array of underlying causes. Although the understanding of cardiogenic shock epidemiology, specific subphenotypes, haemodynamics, and cardiogenic shock severity staging has evolved, few therapeutic interventions have shown survival benefit. Results from seminal randomised controlled trials support early

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Mechanical Ventilation, Respiratory

Personalized mechanical ventilation in acute respiratory distress syndrome

Abstract A personalized mechanical ventilation approach for patients with adult respiratory distress syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging, and biological phenotypes may improve ventilation practice and outcome. However, additional research is warranted before personalized mechanical ventilation strategies can be applied at the bedside. Ventilatory parameters should be titrated based

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Miscellaneous

The Pain Management of Trauma Patients in the Emergency Department

Abstract   The vast majority of injured patients suffer from pain. Systematic assessment of pain on admission to the emergency department (ED) is a cornerstone of translating the best treatment strategies for patient care into practice. Pain must be measured with severity scales that are validated in clinical practice, including for specific populations (such as

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