Abstract The 50th Anniversary Wolf Creek XVIII Conference was hosted by the Max Harry Weil Institute for Critical Care Research and Innovation in Ann Arbor, Michigan, USA on June 19–21,..
Read MoreAbstract Background Refractory cardiac arrest remains a major challenge in children, with poor survival despite advances in cardiopulmonary resuscitation (CPR). Extracorporeal cardiopulmonary resuscitation (ECPR), defined as rapid deployment of extracorporeal..
Read MoreAbstract Background Fulminant myocarditis is a severe cardiac condition characterized by rapid progression and high mortality. In recent years, advancements in medical technology, particularly the application of mechanical circulatory support,..
Read MoreAbstract BACKGROUND: While the immediate goal of cardiopulmonary resuscitation is to achieve return of spontaneous circulation, the patient-centered goal is to minimize neurological injury. Several medications used during cardiac arrest..
Read MoreAbstract Refractory ventricular arrhythmias and cardiac arrest in younger patients are rare, life-threatening events, particularly when standard resuscitation fails. Extracorporeal membrane oxygenation (ECMO) provides temporary circulatory support, enabling hemodynamic stabilization,..
Read MoreAbstract Background Amniotic fluid embolism (AFE) with cardiac arrest is an obstetric emergency with an exceedingly high maternal mortality. Early application of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may provide essential..
Read MoreAbstract Aims The study explores the association between race, survival and neurological outcomes among out-of-hospital cardiac arrest (OHCA) patients listed in Minnesota metro and the University of Minnesota Extracorporeal Cardiopulmonary..
Read MoreAbstract Background Cardiac arrest (CA) remains a leading cause of mortality and long-term neurological disability. In cases of refractory CA, extracorporeal cardiopulmonary resuscitation (ECPR) may be implemented as a salvage..
Read MoreAbstract The use of extracorporeal cardiopulmonary resuscitation (ECPR) has risen exponentially worldwide. Following favorable observational studies, randomized controlled trials yielded conflicting results in patients with out of hospital cardiac arrest..
Read MoreAbstract Background Cardiac rhythm is a well-established prognostic factor in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR); however, existing evidence is primarily limited to small, single-center studies. This study aimed to..
Read MoreAbstract Neuroleptic malignant syndrome (NMS) is a rare, life-threatening hypermetabolic reaction to dopamine-antagonist drugs that may progress to profound rhabdomyolysis, extreme hyperkalemia, and cardiac arrest (CA). Evidence guiding extracorporeal cardiopulmonary..
Read MoreAbstract ECPR Efficacy and Use: Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival and neurologic outcomes in refractory out-of-hospital cardiac arrest, with global adoption and center availability expanding significantly.
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), involving VA-ECMO during refractory cardiac arrest, has been linked to improved outcomes. While systemic anticoagulation is commonly used to prevent circuit thrombosis, bleeding and..
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival for patients experiencing refractory cardiac arrest but is often associated with severe ischemia-reperfusion injury (IRI). Hydrogen gas (H2) has demonstrated promising preclinical..
Read MoreAbstract Lightning strike injuries have a high mortality rate and frequently result in immediate cardiac arrest. Although extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for out-of-hospital cardiac arrest, its role..
Read MoreAbstract Background The COVID-19 Pandemic challenged the healthcare system worldwide, but its effect on outcomes of cardiac arrest (CA) and extracorporeal membrane oxygenation (ECMO) use are understudied. We examined trends..
Read MoreAbstract These European Resuscitation Council (ERC) Guidelines 2025 on Special Circumstances in Resuscitation are based on the 2025 Consensus on Science with Treatment Recommendations (CoSTR) of the International Liaison Committee..
Read MoreAbstract Background Young patients may survive accidental deep hypothermia with prolonged asystolic circulatory arrest because of protective effects of cold. Case Summary An 8-year-old boy fell through pond ice and..
Read MoreAbstract Objective To describe cardiac arrest during anesthesia care provided by a pediatric cardiac anesthesiologist in patients with congenital heart disease and identify predictors of outcome. Design Retrospective chart review...
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (ECPR) is an established intervention for select patients experiencing refractory cardiac arrest. Among modifiable predictors of survival and neurologic recovery during ECPR implementation, timely restoration of..
Read MoreAbstract Introduction Extracorporeal cardiopulmonary resuscitation (eCPR) is a rescue therapy for refractory cardiac arrest, with evidence suggesting improved outcomes when performed at experienced centres. Unlike conventional CPR (cCPR), eCPR patients..
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory cardiac arrest across the world, but its cost-effectiveness remains uncertain. We conducted this systematic review to assess the available..
Read MoreAbstract Background While the clinical effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) has gained increasing attention, its real-world utilization, patient selection, and system-level implementation remain incompletely..
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) can improve outcomes in refractory out-of-hospital cardiac arrest (OHCA), but access is limited by geographic and system constraints. We aimed to compare the potential..
Read MoreAbstract BackgroundCPR-induced consciousness (CPRIC) is defined as consciousness during CPR, ranging from eye opening to combative behaviour and vocalisation, despite the absence of spontaneous circulation. CPRIC has not previously been..
Read MoreAbstract After cardiac arrest, restoration of circulation is the first step toward survivorship. Extracorporeal CPR (ECPR), the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) to restore circulation, is increasingly being..
Read MoreAbstract Aims Pediatric cardiac arrest is associated with high mortality and significant morbidity among survivors. International guidelines for prognostication remain limited due to small heterogeneous patient populations, variable post-return of..
Read MoreAbstract Introduction Cardiac arrest in the emergency department (ED) is a rare event. Prior studies have used dedicated cardiac arrest registries, but few have leveraged “big data” from electronic healthcare..
Read MoreAbstract Objective Cardiac arrest happens in 0.7%-5.2% patients after cardiovascular surgery, and cases with asystole or severe bradycardia need timely temporary pacing. However, routine temporary pacing wire insertion in cardiopulmonary..
Read MoreAbstract Background: Extracorporeal cardiopulmonary resuscitation (eCPR) is a method for initiation of cardiopulmonary bypass during resuscitation of a patient with refractory cardiac arrest to support end-organ perfusion. This retrospective study evaluates..
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