Tags Archives: cardiac arrest

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On-Scene, Residential Extracorporeal Cardiopulmonary Resuscitation for Refractory Out-of-Hospital Cardiac Arrest: Operational and Logistical Considerations

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) is an emerging rescue strategy for select patients with refractory out-of-hospital cardiac arrest (OHCA). Mobile ECPR programs aim to reduce low-flow time by initiating extracorporeal..

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Characteristics and outcomes of younger adults with out-of-hospital cardiac arrest resuscitated with extracorporeal membrane oxygenation: a nationwide study

Abstract Background Extracorporeal cardiopulmonary resuscitation has shown promise in out-of-hospital cardiac arrest, but evidence in younger adults remains limited. Younger adults represent a unique subgroup with distinct etiologies and potentially..

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Time to extracorporeal cardiopulmonary resuscitation flow and outcomes in paediatric in-hospital cardiac arrest: a 12-year single-centre study

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory paediatric in-hospital cardiac arrest (IHCA). Although rapid initiation of extracorporeal life support (ECLS) is widely considered critical, the relative..

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Pediatric Extracorporeal Cardiopulmonary Resuscitation (ECPR): Understanding Variations in Systems and Clinical Practice

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric cardiac arrest relies on enhanced resources and time-critical decision-making. We aimed to evaluate variations in systems and clinical practice among extracorporeal membrane oxygenation..

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Association Between Targeted Temperature Management and New-Onset Brain Disability in in-Hospital Cardiac Arrest Survivors: A Nationwide Cohort Study

Abstract Objectives Targeted temperature management (TTM) is the standard of care for comatose cardiac arrest survivors. However, evidence regarding its long-term neurological impact specifically on in-hospital cardiac arrest (IHCA) survivors..

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Early Prediction of Neurological Outcome After Cardiac Arrest-Rationale and Design of the Prospective International Observational EARLY-NEURO, a STEPCARE Substudy

Abstract Background Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and..

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Cost-effectiveness of extracorporeal CPR for out-of-hospital cardiac arrest: a trial-based Markov model with a lifetime horizon

Abstract Aims Extracorporeal cardiopulmonary resuscitation (ECPR) can restore circulation in refractory out-of-hospital cardiac arrest (OHCA). A trial-based analysis with a 1-year horizon showed limited cost-effectiveness of this demanding procedure. However,..

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Next-generation extracorporeal membrane oxygenation for multi-organ recovery after refractory cardiac arrest

Abstract Introduction: Survival after cardiac arrest and prolonged conventional cardiopulmonary resuscitation remains poor, with out-of-hospital survival rates of only 2%–10%. Conventional veno-arterial extracorporeal membrane oxygenation or extracorporeal cardiopulmonary resuscitation can restore..

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Unexpected Cardiac Arrest After Cardiopulmonary Bypass Initiation, Likely Due to Cardioplegia Migration: A Case Report

Abstract This case report describes a pediatric cardiac surgery in which electrocardiographic (ECG) changes appeared immediately after the initiation of cardiopulmonary bypass (CPB), followed by severe bradycardia and ultimately flaccid..

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Early colonoscopy for detection of colon ischemia after extracorporeal cardiopulmonary resuscitation

Abstract Dear Editor, Extracorporeal cardiopulmonary resuscitation (ECPR) refers to the initiation of venoarterial extracorporeal membrane oxygenation (VA ECMO) during cardiac arrest to restore systemic perfusion with oxygenated blood []. Prolonged..

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Prehospital initiation of extracorporeal life support for refractory out-of-hospital cardiac arrest–results of a prospective observational study

Abstract Background Despite advances in cardiopulmonary resuscitation (CPR), survival after out-of-hospital cardiac arrest (OHCA) remains low. Use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) as extracorporeal CPR (ECPR) may improve..

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The Facilitated hospital-based ECPR via Helicopter Transport (FLIGHT-to-ECPR) Study

Abstract Introduction Survival after out-of-hospital cardiac arrest (OHCA) remains poor, particularly for refractory ventricular fibrillation/ventricular tachycardia (VF/VT). Extracorporeal cardiopulmonary resuscitation (ECPR) improves outcomes when delivered within 60 minutes of low-flow..

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Wolf Creek XVIII Part 4: innovations in ECPR technology

Abstract The 50th Anniversary Wolf Creek XVIII Conference was hosted by the Max Harry Weil Institute for Critical Care Research and Innovation in Ann Arbor, Michigan, USA on June 19–21,..

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Pediatric ECPR as Bridge to Surgery: Successful Management of Refractory Cardiac Arrest in High-Risk ICD Lead Extraction

Abstract Background Refractory cardiac arrest remains a major challenge in children, with poor survival despite advances in cardiopulmonary resuscitation (CPR). Extracorporeal cardiopulmonary resuscitation (ECPR), defined as rapid deployment of extracorporeal..

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Application of VA-ECMO combined with IABP in a patient with cardiac arrest following fulminant myocarditis

Abstract Background Fulminant myocarditis is a severe cardiac condition characterized by rapid progression and high mortality. In recent years, advancements in medical technology, particularly the application of mechanical circulatory support,..

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Impact of Advanced Cardiac Life Support Medications on Discharge Neurological Function for Survivors of Cardiac Arrest When Using ECPR

Abstract BACKGROUND: While the immediate goal of cardiopulmonary resuscitation is to achieve return of spontaneous circulation, the patient-centered goal is to minimize neurological injury. Several medications used during cardiac arrest..

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Breaking the Rhythm: Extracorporeal Membrane Oxygenation (ECMO) as a Life Saver in a Case of Resistant Arrhythmia and Cardiac Arrest

Abstract Refractory ventricular arrhythmias and cardiac arrest in younger patients are rare, life-threatening events, particularly when standard resuscitation fails. Extracorporeal membrane oxygenation (ECMO) provides temporary circulatory support, enabling hemodynamic stabilization,..

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The importance of early veno-arterial extracorporeal membrane oxygenation in the management of amniotic fluid embolism complicated by cardiac arrest: a…

Abstract Background Amniotic fluid embolism (AFE) with cardiac arrest is an obstetric emergency with an exceedingly high maternal mortality. Early application of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may provide essential..

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Racial differences in cardiac arrest survival: insights from Minnesota metro data and the University of Minnesota extracorporeal cardiopulmonary resuscitation cohort

Abstract Aims The study explores the association between race, survival and neurological outcomes among out-of-hospital cardiac arrest (OHCA) patients listed in Minnesota metro and the University of Minnesota Extracorporeal Cardiopulmonary..

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Effects of therapeutic hypothermia on brain function in a refractory cardiac arrest model treated with extracorporeal cardiopulmonary resuscitation

Abstract Background Cardiac arrest (CA) remains a leading cause of mortality and long-term neurological disability. In cases of refractory CA, extracorporeal cardiopulmonary resuscitation (ECPR) may be implemented as a salvage..

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Extracorporeal cardiopulmonary resuscitation: what does the future hold for out of hospital cardiac arrest? A narrative review and critical appraisal…

Abstract The use of extracorporeal cardiopulmonary resuscitation (ECPR) has risen exponentially worldwide. Following favorable observational studies, randomized controlled trials yielded conflicting results in patients with out of hospital cardiac arrest..

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Impact of rhythm changes during CPR on ECPR outcomes: an ELSO Registry study

Abstract Background Cardiac rhythm is a well-established prognostic factor in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR); however, existing evidence is primarily limited to small, single-center studies. This study aimed to..

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Extracorporeal Cardiopulmonary Resuscitation in Cardiac Arrest Associated to Neuroleptic Malignant Syndrome: A Case Report

Abstract Neuroleptic malignant syndrome (NMS) is a rare, life-threatening hypermetabolic reaction to dopamine-antagonist drugs that may progress to profound rhabdomyolysis, extreme hyperkalemia, and cardiac arrest (CA). Evidence guiding extracorporeal cardiopulmonary..

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State-of-the-Art Update in Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital Cardiac Arrest

Abstract ECPR Efficacy and Use: Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival and neurologic outcomes in refractory out-of-hospital cardiac arrest, with global adoption and center availability expanding significantly.

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Anticoagulation-free strategy within the first 24 h of extracorporeal cardiopulmonary resuscitation in refractory cardiac arrest patients: a retrospective cohort study

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), involving VA-ECMO during refractory cardiac arrest, has been linked to improved outcomes. While systemic anticoagulation is commonly used to prevent circuit thrombosis, bleeding and..

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Hydrogen’s Feasibility and Safety as a Therapy in Extracorporeal Cardiopulmonary Resuscitation (Hydrogen-FAST): study protocol for a trial of inhaled hydrogen…

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) improves survival for patients experiencing refractory cardiac arrest but is often associated with severe ischemia-reperfusion injury (IRI). Hydrogen gas (H2) has demonstrated promising preclinical..

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Lightning Strike-Induced Cardiac Arrest Managed With Extracorporeal Cardiopulmonary Resuscitation: A Case Report

Abstract Lightning strike injuries have a high mortality rate and frequently result in immediate cardiac arrest. Although extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for out-of-hospital cardiac arrest, its role..

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Trends and outcomes of cardiac arrest and extracorporeal membrane oxygenation during the COVID-19 pandemic in the United States

Abstract Background The COVID-19 Pandemic challenged the healthcare system worldwide, but its effect on outcomes of cardiac arrest (CA) and extracorporeal membrane oxygenation (ECMO) use are understudied. We examined trends..

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European Resuscitation Council Guidelines 2025 Special Circumstances in Resuscitation

Abstract These European Resuscitation Council (ERC) Guidelines 2025 on Special Circumstances in Resuscitation are based on the 2025 Consensus on Science with Treatment Recommendations (CoSTR) of the International Liaison Committee..

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Ice Water Drowning Survival After 147-Minute Submersion and 7 °C Hypothermic Circulatory Arrest

Abstract Background Young patients may survive accidental deep hypothermia with prolonged asystolic circulatory arrest because of protective effects of cold. Case Summary An 8-year-old boy fell through pond ice and..

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