Antibiotics archivos - Perfusfind Intensive Care

Ventilator-associated pneumonia: mechanisms, an appraisal of current therapies and the role for inhaled antibiotics in prevention and treatment

Summary Ventilator-associated pneumonia (VAP), the most common healthcare-associated infection in the ICU, significantly increases healthcare costs and negatively impacts patient outcomes. The review outlines complex VAP pathophysiology, involving abnormal microbiota colonization and micro-aspiration associated with mechanical ventilation. Traditional intravenous antibiotic therapies face challenges such as systemic complications and antibiotic resistance, while inhaled antibiotics offer a […]

Antibiotics, inhaled antibiotics, mechanical ventilation, pneumonia, ventilator

Ventilator-associated pneumonia: mechanisms, an appraisal of current therapies and the role for inhaled antibiotics in prevention and treatment Read Post »

Miscellaneous

Invasive fungal infections in patients with liver disease: immunological and clinical considerations for the intensive care unit

Abstract Patients with liver disease in the intensive care unit (ICU) face a unique susceptibility to infection due to the complex immune dysfunction resulting from hepatic failure. Bacterial infections are commonly present in these patients upon arrival to the hospital, often being the primary reason for ICU admission. In contrast, invasive fungal infections (IFIs) afflict

Antibiotics, antifungal, aspergillus, invasive fungal infections (IFIs), Invasive Pulmonary Aspergillosis (IPA), liver disease

Invasive fungal infections in patients with liver disease: immunological and clinical considerations for the intensive care unit Read Post »

Respiratory

Inhaled antibiotics for treating pneumonia in invasively ventilated patients in intensive care unit: a meta-analysis of randomized clinical trials with trial sequential analysis

Abstract Background The use of inhaled antibiotics for treating pneumonia in invasively ventilated patients offers a direct approach, allowing for high local concentrations of the drug in the lower respiratory tract while simultaneously reducing systemic toxicity. However, the real efficacy and safety of nebulized antibiotics remain unclear. The aim of the present is to assess

Antibiotics, infection, Inhaled, invasive ventilation, Multi-drug resistant, Multi-drug resistant organism, pneumonia

Inhaled antibiotics for treating pneumonia in invasively ventilated patients in intensive care unit: a meta-analysis of randomized clinical trials with trial sequential analysis Read Post »