acute hypoxemic respiratory failure (AHRF)

Mechanical Ventilation

Association between controlled mechanical ventilation and systemic inflammation in acute hypoxemic respiratory failure: an observational cohort study

Summary Why This Study Matters This study provides rare human clinical data linking spontaneous breathing during AHRF, ventilation distribution on EIT, and systemic inflammation (IL-6). It helps clarify when transitioning from non-invasive support to controlled mechanical ventilation may reduce physiologic stress and potential P-SILI. 1. What the Investigators Wanted to Know The study examined whether […]

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Respiratory

Limitations of SpO2 / FiO2-ratio for classification and monitoring of acute respiratory distress syndrome—an observational cohort study

Abstract Background The ratio of pulse-oximetric peripheral oxygen saturation to fraction of inspired oxygen (SpO2/FiO2) has been proposed as additional hypoxemia criterion in a new global definition of acute respiratory distress syndrome (ARDS). This study aims to evaluate the clinical and theoretical limitations of the SpO2/FiO2-ratio when using it to classify patients with ARDS and

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Limitations of SpO2 / FiO2-ratio for classification and monitoring of acute respiratory distress syndrome—an observational cohort study Read Post »

Miscellaneous, Respiratory

Distribution of airway pressure opening in the lungs measured with electrical impedance tomography (POET): a prospective physiological study

Abstract Background In patients with acute hypoxemic respiratory failure (AHRF) under mechanical ventilation, the change in pressure slope during a low-flow insufflation indicates a global airway opening pressure (AOP) needed to reopen closed airways and may be used for titration of positive end-expiratory pressure. Objectives To understand 1) if airways open homogeneously inside the lungs

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Distribution of airway pressure opening in the lungs measured with electrical impedance tomography (POET): a prospective physiological study Read Post »

Respiratory

High-flow nasal oxygen is the reference treatment in acute hypoxemic respiratory failure: Con

Abstract Over the past decade and boosted by the coronavirus disease 2019 (COVID-19) pandemic, high-flow nasal oxygen (HFNO) has been increasingly used in the intensive care unit (ICU) to treat acute hypoxemic respiratory failure (AHRF). In this review, we show that despite this wide and rapid increase in the use of HFNO to treat AHRF,

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High-flow nasal oxygen is the reference treatment in acute hypoxemic respiratory failure: Con Read Post »

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