Tags Archives: heart transplantation

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Simultaneos Heart - Liver transplantation

  1. Preoperative Planning & Coordination •Multidisciplinary alignment (cardiac surgery, transplant hepatology, anesthesia, perfusion) •Donor organ assessment and synchronized timing of procurement •Hemodynamic optimization and coagulation planning •blood products (massive..

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Net Prolongation of Life in Advanced Heart Failure: An Intentional Strategy of Durable LVAD Therapy Followed by Heart Transplantation

Abstract Heart transplantation (HT) and durable left ventricular assist device (LVAD) support are established surgical treatment options for patients with end-stage systolic heart failure (HF) and/or nonrecoverable cardiogenic shock. HT..

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Heart Procurement and Putting the Heart on OCS Machine with Perfusionist

    Heart Procurement and Placement on OCS – Stepwise Approach   I. Preoperative Preparation   1.Team Preparation •Confirm donor consent and organ allocation. •Communicate with recipient surgical team and..

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A Perioperative Blood Conservation Protocol to Achieve Successful Bloodless Heart Transplantation

Abstract Heart transplantation (HT) is the definitive therapy for end-stage heart failure. Patients unwilling to receive blood product transfusions are often considered ineligible for HT due to the significant perioperative..

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Shaping the Future of Partial Heart Transplantation: Innovations and Emerging Applications

Abstract Introduction Partial heart transplantation (PHT) represents a novel and adaptable approach to cardiac surgery, allowing for patient-specific and disease-specific interventions while expanding the donor pool and improving organ stewardship...

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Intraoperative antithrombotic drug removal during heart transplantation: A case series from the International Safe and Timely Antithrombotic Removal (STAR) registry1

Abstract Background Patients on heart transplant waiting lists are often on antithrombotic (AT) drugs. Emergency orthotopic heart transplantation (OHT) when performed on such patients without optimal washout periods increases the..

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Heart transplant ( rapid sequence)

A quick explanation of heart transplantation.   Dr.Sam Zeraatian Nejad Davani, Attending Professor of Cardiovascular Surgery and Head of Department of Transplant and OPO of IUMS and Superfellowship of Advanced..

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Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry

Abstract BACKGROUND: A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated favorable outcomes in hearts recovered..

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Heart transplantation following donation after euthanasia

Abstract Heart transplantation (HT) is markedly constrained due to a critical shortage of suitable organs from donors in brain death (DBD). Transplantation of hearts donated after circulatory death (DCD) has..

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BTT-ECMO Trends and Outcomes Under Revised Heart Allocation System

Abstract Under the revised UNOS heart allocation system, waitlist and post-transplant outcomes among patients bridged to transplant with VA-ECMO (BTT-ECMO) have improved. However, it remains largely unknown if these early..

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Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation

Abstract Open-lung ventilation during cardiopulmonary bypass (CPB) in patients undergoing heart transplantation (HTx) is a potential strategy to mitigate postoperative acute respiratory distress syndrome (ARDS). We utilized an ovine HTx..

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Surgical Technique of Donation after Circulatory Death using Normothermic Regional Perfusion

Abstract Heart transplantation (HT) is the gold standard treatment of end-stage heart disease. Waitlist mortality remains high due to a shortage of available donor organs. Donation after circulatory death (DCD)..

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Heart Transplantation and Left Ventricular Assist Devices: Long-Term Prognosis and Effects on Mental Health

Abstract Heart transplantation and left ventricular assist devices (LVADs) have emerged as crucial interventions for end-stage heart failure, dramatically improving patient outcomes. This narrative review examines their historical context, indications,..

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Heart transplantation using donation after circulatory death in the United States

Abstract Objectives Heart donation after circulatory death was recently reintroduced in the United States with hopes of increasing donor heart availability. We examined its national use and outcomes. Methods The..

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Beating Heart Transplantation: How to Do It

Abstract Heart transplantation utilizing deceased after circulatory death (DCD) donors has expanded the donor pool through the use of ex vivo normothermic perfusion. Compared with brain death donation, the conventional..

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Overcoming the 24-Hour Heart Transplant Time Limit: New Transplant Technique Could Save Lives

Significant advancements in preservation techniques could liberate more hearts for transplantation. More than five decades after the first human-to-human heart transplant, over 5,000 heart transplants are performed annually worldwide. However,..

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Use of intraoperative haemoadsorption in patients undergoing heart transplantation: a proof-of-concept randomized trial

Abstract Aims The aim of this trial was to compare the clinical effects of intraoperative haemoadsorption versus standard care in patients undergoing orthotopic heart transplantation (OHT). Methods and results In..

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Heart Transplantation From DCD Donors in Australia: Lessons Learned From the First 74 Cases

Abstract Heart transplantation from donation after circulatory death (DCD) donors has the potential to substantially increase overall heart transplant activity. The aim of this report is to review the first..

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The Use of Impella 5.5 for Donor–Heart Hemodynamic Support in Heart Transplantation

Abstract Primary graft dysfunction is a feared complication and cause of mortality post–heart transplant. Primary graft dysfunction may require mechanical circulatory support, such as venoarterial extracorporeal membrane oxygenation, which carries..

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Ambulation of Patients With In Situ Femoral Intraaortic Balloon Pump While Awaiting Heart Transplantation

Abstract With the implementation of the new allocation system in the United States on October 18, 2018, patients requiring temporary mechanical circulatory support (tMCS) have the highest priority, a shorter..

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The 2023 International Society for Heart and Lung Transplantation Guidelines for Mechanical Circulatory Support: A 10- Year Update

Abstract In 2013, the International Society for Heart and Lung Transplantation (ISHLT) published the first official guidelines for implantable mechanical circulatory support (MCS) as commissioned by its Board of Directory...

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Partial Heart Transplantation in Adult Cardiac Surgery

Abstract Many young adults require heart valve replacements. Current options for valve replacement in adults include mechanical valves, bioprosthetic valves, or the Ross procedure. Of these, mechanical and bioprosthetic valves..

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First Successful Human Coronary Artery Bypass Surgery Postoperative Heart Transplant: A Case Report

Abstract Heart transplant is now the treatment of choice for patients with advanced heart failure who are refractory to medical treatment. With a small number of candidates who meet the..

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Molecules, Machines, and the Perfusate Milieu: Organ Preservation and Emerging Concepts for Heart Transplant

Abstract Heart transplant remains the most durable treatment for end-stage congestive heart failure. Since the first successful human heart transplant performed by Barnard in 1967, advances in organ procurement, understanding..

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Donation After Circulatory Death in Heart Transplantation: History, Outcomes, Clinical Challenges, and Opportunities to Expand the Donor Pool

Abstract Heart transplantation remains the gold-standard therapy for end-stage heart failure; the expected median survival range is 12–13 years. More than 30,000 heart transplants have been performed globally in the..

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Reinnervation post-heart transplantation

Abstract Heart transplantation results in complete denervation of the donor heart with loss of afferent and efferent nerve connections. The majority of patients remain completely denervated during the first 6–12..

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Outcome of primary graft dysfunction rescued by venoarterial extracorporeal membrane oxygenation after heart transplantation

Abstract Background: Primary graft dysfunction remains the leading cause of 30-day mortality after heart transplantation. Few data have been published about the clinical outcome of severe primary graft dysfunction treated..

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The application of autopsy and explanted heart samples in scientific research

Abstract Cardiovascular disease, which accounts for nearly one-third of deaths globally, is a great threat to human life and health. To improve global health and advance the progression of cardiovascular..

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Use of the CytoSorb® filter for elimination of residual therapeutic argatroban concentrations during heparinized cardiopulmonary bypass for heart transplantation

This case reports on a 34-year-old male patient with a medical history of corrected Fallot tetralogy, who was scheduled for heart transplantation. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/06/CoW_25_2022_E_web_compressed.pdf"]

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Controlled temperatures in cold preservation provides safe heart transplantation results

Abstract Background We aimed to investigate the short-term outcomes of heart transplant patients who underwent SherpaPak™ donor organ preservation. Method We prospectively collected the data of patients who underwent heart..

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