Abstract Cardiopulmonary bypass (CPB) is one of the most groundbreaking medical innovations in history, enabling safe and effective heart surgery by temporarily replacing the function of the heart and lungs...
Read MoreAbstract Objectives Systemic inflammatory response syndrome (SIRS) is a common complication following cardiopulmonary bypass (CPB), associated with increased mortality. We assessed the relationship between indexed oxygen delivery (DO2i) during CPB..
Read MoreAbstract CARDIOPULMONARY BYPASS (CPB) is an essential component of cardiac surgery, and its unexpected failure during surgery can compromise circulatory and respiratory management, potentially endangering the patient's life. In the..
Read MoreAbstract To investigate the feasibility of regional oxygen saturation (rSO2) monitoring for preventing acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) caused by cardiopulmonary bypass (CPB) in infants undergoing ventricular..
Read MoreAbstract Cardiopulmonary bypass serves as a cornerstone in cardiac surgery, enabling life-sustaining circulatory and respiratory support during complex procedures that necessitate the temporary cessation of cardiac activity. This intricate process..
Read MoreAbstract Activation of the alternative complement pathway by artificial extracorporeal surfaces is relevant to several clinical applications such as cardiac surgery with cardiopulmonary bypass (CPB), thoracic organ transplantation and hemodialysis...
Read MoreAbstract Transcatheter aortic valve implantation (TAVI) has revolutionized the treatment of severe aortic stenosis in high-risk patients, offering a minimally invasive alternative to open-heart surgery. However, complications such as hemodynamic..
Read MoreAbstract Studies into the mechanisms of cardiopulmonary bypass-associated acute lung injury have not presented breakthroughs for many years, resulting in the stagnation of management strategies and clinical medicine measures. This..
Read MoreAbstract Postoperative organ dysfunction remains a major challenge in adult cardiac surgery with cardiopulmonary bypass (CPB), frequently involving the kidneys, heart, and lungs. These complications are primarily driven by hemolysis,..
Read MoreAbstract We read with great interest the article by Kowara et al.,[] which highlights the potential of PvCO2 × Ve/Q as a key predictive marker for hyperlactatemia during cardiopulmonary bypass (CPB). This..
Read MoreAbstract Background: Cardiac surgery with cardiopulmonary bypass (CPB) is associated with impaired renal oxygenation and acute kidney injury. We investigated whether a higher than our standard blood flow during CPB..
Read MoreAbstract Background During cardiopulmonary bypass (CPB), which is frequently utilized in open-heart surgery, the maintenance of circulation in a non-physiological environment may lead to alterations in the properties of circulating..
Read MoreAbstract Background Despite sternum sparing and without cardiopulmonary bypass, the actual value of minimally invasive coronary surgery (MICS) is still debatable. This study aimed to compare the completeness of revascularization..
Read MoreAbstract Introduction: In cardiopulmonary bypass (CPB), blood circulation is temporarily maintained by an artificial blood-pumping device during cardiac surgery. Worldwide, approximately half of the CPB procedures utilize either centrifugal or..
Read MoreAbstract Introduction Increased time-dose-response (TDR) of suboptimal oxygen delivery (DO2) during cardiopulmonary bypass (CPB) has been associated with increased postoperative complications. The impact of surgical approach - minimally invasive vs...
Read MoreAbstract Background Cardiopulmonary bypass use during surgery disrupts microcirculation, which can contribute to lung injury, particularly in patients with pulmonary comorbidities. Continuous transcutaneous carbon dioxide (CO2) monitoring assists clinicians to..
Read MoreAbstract This study assesses hemodynamic data and parameter combinations in predicting neurocognitive impairment post-cardiopulmonary bypass graft (CABG) using logistic regression and random forest algorithms. 28 patients underwent the Montreal Cognitive..
Read More1. Introduction Sickle Cell Disease (SCD) is a chronic, inherited blood disorder resulting from a single point mutation in the β-globin gene. This mutation leads to the production of hemoglobin..
Read MoreIn modern cardiac surgery, cardiopulmonary bypass (CPB) plays a life-saving role. It allows the heart to be stopped safely while the body is perfused with oxygenated blood. However, it’s a..
Read MoreAbstract BACKGROUND Cardiopulmonary bypass (CPB) is a life-support technology widely used in surgery. Review articles reflect research advances in a certain topic or field within a certain period of time...
Read MoreAbstract Introduction: Indexed oxygen delivery (DO₂i) is a critical parameter in cardiopulmonary bypass (CPB) management. Traditional goal-directed perfusion (GDP) protocols use fixed DO₂i thresholds, typically derived from normothermic conditions. However,..
Read MoreAbstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size..
Read MoreAbstract Introduction Cardiopulmonary bypass (CPB) is essential for cardiac surgery but poses risks, including gaseous micro emboli (GME). While the incidence of stroke—a common clinical consequence of embolism—ranges from 1-5%..
Read MoreAbstract A venous reservoir (VR) is crucial for safe blood volume regulation during cardiopulmonary bypass (CPB) procedures. Currently, blood volume measurement in VRs relies heavily on visual inspection, which limits..
Read MoreAbstract IMPORTANCE: Cardiopulmonary bypass (CPB) surgery is associated with changes in the intestinal microbiome. Metabolism of tryptophan into the indole pathway is entirely facilitated by the intestinal microbiome, and indole..
Read MoreAbstract Background The nadir oxygen delivery index (DO2i) during cardiopulmonary bypass (CPB) is reportedly associated with acute kidney injury (AKI) in patients undergoing cardiac surgery. However, there are few reports..
Read MoreAbstract Patients undergoing cardiopulmonary bypass (CPB) often experience neurological complications, but the neurobiological mechanisms remain unclear. This study combined resting-state fMRI, structural MRI, and cognitive testing to examine brain changes..
Read MoreAbstract OBJECTIVES The question whether minimally invasive extracorporeal circulation (MiECC) represents the optimal perfusion strategy in cardiac surgery remains unanswered. We sought to systematically review the entire literature and thoroughly..
Read MoreAbstract Background: This study aimed to investigate the effect of operative and postoperative parameters on late-onset hyperlactatemia (LOHL) after cardiac surgery in the pediatric patient population.Methods: One hundred fifty-nine ventricular septal defect..
Read MoreAbstract Background There remains significant variability in the use of intraoperative mechanical circulatory support in lung transplantation. This report details our outcomes using elective cardiopulmonary bypass (CPB) in lung transplantation...
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