Abstract Background Bleeding and thrombosis are major complications of micro-axial flow pump (mAFP) support in cardiogenic shock (CS), yet contemporary data on their incidence, temporal trends, and prognostic impact remain..
Read MoreAbstract Background Major bleeding is a common and serious complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO). Current perspectives on bleeding risk fail to reflect dynamic changes over time in..
Read MoreAbstract Objective So far, evidence is scarce regarding the impact of rewarming temperature on bleeding after cardiac surgery under cardiopulmonary bypass (CPB). We seek to evaluate how rewarming temperature affects..
Read MoreAbstract Background The microaxial flow pump (mAFP) has demonstrated improved outcomes in selected patients with ST-segment elevation acute myocardial infarction and cardiogenic shock (STEMI-CS). However, its use has been associated..
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR), an emerging resuscitative therapy following refractory cardiac arrests, is associated with hemorrhagic complications that potentially affect patient outcomes. Objectives This study evaluated the risks..
Read MoreAbstract Importance Platelet transfusion is critical in managing major bleeding, but access to liquid-stored platelets is limited by their 5- to 7-day shelf life. Cryopreserved platelets last up to 2 years..
Read MoreAbstract Background Coronary artery bypass grafting (CABG) carries a high risk of bleeding and allogeneic blood transfusions, both associated with poor outcomes. We assessed perioperative transfusions and factors associated with..
Read MoreAbstract Background Postoperative bleeding is a major concern in cardiac surgery, often leading to significant transfusion requirements. Despite this high transfusion demand, the use of postoperative autologous blood transfusion (PABT)..
Read MoreAbstract Objectives Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO) support. While chest tube treatment is infrequently linked to bleeding in non-ECMO patients, several reports suggest a markedly..
Read MoreAbstract The utilisation of cardiopulmonary bypass (CPB) during cardiac surgery is often associated with complex haemostatic perturbations, frequently manifesting as a paradoxical risk of both bleeding and thrombosis. This is..
Read MoreAbstract Purpose Fibrinogen is widely used in cardiac surgery. Still, reported associations between plasma fibrinogen level and chest tube drainage are weak. The results of trials on fibrinogen supplementation are..
Read MoreAbstract Purpose Postoperative bleeding is a major concern in pediatric cardiac surgery under cardiopulmonary bypass (CPB). The comparative utility of viscoelastic testing and central laboratory assays for predicting bleeding risk..
Read MoreAbstract Introduction Patients who undergo cardiac surgery have a high risk of significant blood loss and anemia. While allogeneic red blood cell (RBC) transfusions are effective, they are associated with..
Read MoreAbstract Introduction Bleeding events are common during the provision of Venoarterial ECMO (VA ECMO). Previous observational has suggested that these bleeding events are associated with an increased risk of in-hospital..
Read MoreAbstract Objectives Activated recombinant factor VII (rFVIIa) has been used to treat cardiac surgical bleeding in an off-label manner. Due to the high risk of mortality with ongoing hemorrhage, assessing..
Read MoreAbstract Objectives To compare effectiveness and safety of rescue therapy approach with recombinant Factor VII activated (rFVIIa) for refractory bleeding in cardiac surgery compared with a propensity-score-matched control group at..
Read MoreAbstract BACKGROUND: Major bleeding after cardiac surgery is still a relatively common complication, requiring red blood cell (RBC) transfusions and use of procoagulants. The existing guidelines recommend a bleeding management..
Read MoreAbstract Purpose To assess whether prone positioning (PP) increases bleeding risk compared to supine positioning in ARDS patients undergoing veno venous Extracorporeal Membrane Oxygenation (VV ECMO). Materials and Methods A..
Read MoreAbstract Introduction Bleeding and thrombosis are major causes of morbidity and mortality in pediatric extracorporeal membrane oxygenation (ECMO), yet their evolving, time-dependent risks remain poorly defined. This study evaluated clinical..
Read MoreAbstract Objectives The platelet trigger at which to transfuse platelets to prevent bleeding complications in patients supported with extracorporeal membrane oxygenation (ECMO) is unclear. We aimed to elucidate the association..
Read MoreAbstract Introduction Cardiac surgery remains a high-risk procedure for bleeding despite advances in patient blood management. Conventional centrifugation-based autotransfusion devices primarily recover red blood cells, losing platelets and coagulation factors. The..
Read MoreAbstract Objective: To identify risk factors for bleeding and thrombotic complications during extracorporeal membrane oxygenation (ECMO) support in adults and to develop a predictive model based on these factors...
Read MoreAbstract Bleeding complications are frequently observed in patients undergoing extracorporeal membrane oxygenation and are associated with increased mortality. Due to the complex mechanisms, managing bleeding during ECMO remains a challenge...
Read MoreAbstract Bleeding and transfusion during cardiac surgery are major sources of complications. Surgery and cardiopulmonary bypass can induce coagulopathy, including platelet dysfunction. Desmopressin has been shown to reduce bleeding and..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) supports severe cardiorespiratory failure but carries a significant bleeding risk. This systematic review aims to report bleeding definitions in studies involving neonates and children treated..
Read MoreAbstract Objectives To study the association between bleeding and acute kidney injury (AKI). Design Post-hoc study of a randomized trial of 4% albumin versus Ringer's acetate for cardiopulmonary bypass priming..
Read MoreAbstract Introduction Bleeding and thrombotic complications are common in extracorporeal membrane oxygenation (ECMO) patients and are associated with increased mortality and morbidity. The optimal anticoagulation monitoring protocol in these patients..
Read MoreAbstract Introduction Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is an essential life-support system in critical care specifically engineered to assist cardiac and respiratory function by externally maintaining blood perfusion and oxygenation..
Read MoreAbstract Importance Excessive bleeding is a common and prognostically important complication of cardiac surgery. For bleeding related to coagulation factor deficiency, frozen plasma is the most used therapy. Preliminary trials indicate..
Read MoreAbstract Objectives Severe perioperative bleeding occurs in over 30 % of patients on ticagrelor undergoing isolated coronary artery bypass grafting (i-CABG) before completing the recommended 3-day washout. Intraoperative ticagrelor removal with..
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