Tags Archives: Acute kidney injury (AKI)

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Association between intrarenal venous flow and postoperative acute kidney injury in cardiac surgery patients following cardiopulmonary bypass: a prospective cohort…

Abstract Objective Postoperative acute kidney injury (AKI) after cardiac surgery is a major complication that worsens patient outcomes and increases healthcare costs. This study aimed to investigate the association between..

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Association of the red cell distribution with to total serum calcium ratio with severe AKI in patients undergoing cardiac surgery:…

Abstract Background Acute kidney injury (AKI) is a common complication following cardiac surgery. The RCR (ratio of RDW to total serum calcium (TSC)), which exhibits high predictive value for various..

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Exploring carboxyhemoglobin as a predictive marker of hemolysis-related CSA-AKI

Abstract Background Cardiac surgery–associated acute kidney injury (CSA-AKI) is one of the most frequent complications after cardiopulmonary bypass (CPB), in which hemolysis plays an important pathophysiological role. Carboxyhemoglobin (COHb) plays..

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Low cardiac index during periods of arterial hypotension and risk of acute kidney injury in cardiac surgery

Abstract Background Cardiac index (CI) and mean arterial pressure (MAP) are concurrent determinants of renal perfusion. Hypotension is associated with acute kidney injury (AKI), but clinical trials focused solely on..

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Renal pulsatility index assessment by intraoperative doppler ultrasound is associated with acute kidney injury after cardiac surgery: a prospective observational…

Abstract Background Acute kidney injury (AKI) is a common complication among patients undergoing cardiac surgery. Perioperative ultrasound assessment of renal hemodynamic parameters has emerged as a potential tool for predicting..

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Hypothermia exacerbates kidney injury during extracorporeal cardiopulmonary resuscitation

Abstract Objective Kidney injury is one of the most common complications of extracorporeal cardiopulmonary resuscitation (ECPR), yet the renoprotective effects of temperature management during ECPR remain inconclusive. This study aimed..

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Association Between Core Body Temperature at the Time of Separation From Cardiopulmonary Bypass and Postoperative Acute Kidney Injury: A Retrospective…

Abstract Objectives Although hyperthermic perfusion (arterial outlet temperature >37°C) during cardiopulmonary bypass (CPB) is associated with acute kidney injury (AKI), the impact of body temperature at the time of separation..

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Integrated or Parallel Configurations for Renal Replacement Therapy in Patients on VenoArterial Extracorporeal Membrane Oxygenation, a Single Center Retrospective Study

Abstract Background Acute kidney injury (AKI) is frequent in patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO), largely due to the severity of cardiogenic shock and multiorgan failure. Renal replacement..

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Impacts of preoperative kidney function and acute kidney injury on long-term kidney failure after cardiac surgery: a registry-based cohort study

Abstract Background Acute kidney injury is a common complication of cardiac surgery and may lead to kidney failure. In a large sample sourced from national registries, we estimated the risk..

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Predicting acute kidney injury after CABG: Identification of modifiable intraoperative risk factors

Abstract Aim Acute kidney injury (AKI) is a major complication of coronary artery bypass grafting (CABG). Existing predictive models show limited accuracy and rarely include modifiable intraoperative risk factors. Therefore,..

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Prognostic Value of Red Blood Cell Distribution Width in Predicting Acute Kidney Injury After Cardiac Surgery: A Retrospective Cohort Study

Abstract Background/Objectives: Acute kidney injury (AKI) remains a significant complication following cardiac surgery, associated with increased morbidity and mortality. The early detection of AKI is limited by the cost, availability,..

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Perioperative multivariate analysis and risk prediction of acute kidney injury after cardiac surgery: Based on dynamic temperature changes during cardiopulmonary…

Abstract Background Temperature variations during  (CPB) may significantly contribute to the development and progression of  (AKI) after cardiac surgery. We tested the hypothesis that temperature time-series variables during CPB are associated with..

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Early Prediction of Postoperative Peritoneal Dialysis Using Lung Ultrasound Scoring in Neonates After Cardiopulmonary Bypass

Abstract Background: Neonates and young infants undergoing cardiac surgery with cardiopulmonary bypass (CPB) are highly vulnerable to pulmonary dysfunction, systemic inflammation, capillary leak, and fluid overload, which may lead to..

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The Association Between Early Postoperative Temperature Trajectories and Severe Acute Kidney Injury After Valvular Heart Surgery: A Retrospective Cohort Study

Abstract Background/Objectives: Postoperative body temperature abnormalities are common yet underrecognized, and their association with acute kidney injury (AKI) remains unclear. In this study, we aimed to identify early postoperative temperature..

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Exploring the Role of Central Venous Pressure in Cardiac Surgery-Associated Acute Kidney Injury: A Comprehensive Scoping Review

Abstract Background: Acute kidney injury (AKI) is a critical complication, affecting up to 30% of coronary artery bypass grafting (CABG) patients, and contributing to significant morbidity and mortality. Recent studies indicate..

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Hemolysis and Acute Kidney Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Patients With Preexisting Renal Dysfunction

Abstract Objectives Acute kidney injury (AKI) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). This study investigated whether cell-free hemoglobin (CFHb) levels after CPB are associated with..

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Rhabdomyolysis-Associated Acute Kidney Injury: From Pathogenic Mechanisms to the Therapeutic Use of Sorbents

Abstract Background: Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..

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Extracorporeal membrane oxygenation, acute kidney injury, fluid balance, and continuous renal replacement therapy: Acute Disease Quality Initiative (ADQI) and Extracorporeal…

Abstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized for life-threatening cardiac and/or respiratory failure refractory to conventional treatment. Acute kidney injury (AKI) and fluid balance disorders commonly occur both..

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Rhabdomyolysis-associated Acute Kidney Injury: from pathogenic mechanisms to the therapeutic use of sorbents

Abstract Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..

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Profile of Acute Kidney Injury in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass Machine

Abstract Introduction Acute kidney injury (AKI) is a well-known serious complication of cardiopulmonary bypass (CPB) surgery and one of the significant risk factors for mortality, prolonged hospital stay, and additional..

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Machine learning for the prediction of acute kidney injury post cardiac surgery: a systematic review and meta-analysis

Abstract Background and objectives Cardiac surgery associated acute kidney injury can lead to increased morbidity, mortality, and hospitalization. The available risk assessment tools have limited predictive ability. Machine learning has..

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Hypoperfusion and cardiac surgery-associated major adverse kidney events: a single-center retrospective cohort study

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious complication, significantly increasing postoperative morbidity and mortality. We aimed to evaluate whether intraoperative peripheral perfusion index (PPI)..

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Balancing flow and filtration: AKI during ECMO

Abstract Acute Kidney Injury (AKI) cannot be viewed as a mere complication in critically ill patients who require extracorporeal membrane oxygenation (ECMO). Rather, it is being increasingly recognized as an..

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Association of duration of amino acids infusion and renal protection: a secondary analysis of the PROTECTION trial

Abstract Background Intravenous amino acids (AA) reduce acute kidney injury (AKI) in adult patients undergoing cardiac surgery. Because the optimal duration of AA infusion is unknown, we investigated the effect..

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Lean body weight-indexed O2 delivery during cardiopulmonary bypass and acute kidney injury

Abstract Introduction Monitoring indexed oxygen delivery (DO2i) is recommended during cardiopulmonary bypass (CPB) and a predictor of acute kidney injury (AKI). The use of lean body mass-adjusted blood flow rates..

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Postoperative red cell distribution width to platelet ratio is related to cardiac surgery-associated acute kidney injury

Abstract Background This study aimed to investigate the predictive value of the red cell distribution width-to-platelet ratio (RPR) for cardiac surgery-associated acute kidney injury (CSA-AKI). Methods A retrospective analysis of..

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Renal regional oxygenation during pediatric cardiac surgery predicts acute kidney injury: a prospective cohort study with model comparisons

Abstract Background Acute kidney injury (AKI) is a common complication after pediatric cardiac surgery using cardiopulmonary bypass (CPB). This study evaluated renal regional oxygen saturation (R-rSO₂), measured via near-infrared spectroscopy..

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Influence of Pre-emptive Haptoglobin on Postoperative Acute Kidney Injury in Cardiac Surgical Patients: A Randomized Controlled Trial

Abstract BACKGROUND:  Haptoglobin may reduce hemolysis-induced kidney injury in patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB). Haptoglobin may be given empirically when hemolytic urine is observed, or pre-emptively when..

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Tissue perfusion pressure: A novel hemodynamic measure to assess risk of acute kidney injury after cardiac surgery

Abstract Background Optimal hemodynamic targets for preventing acute kidney injury (AKI) have remained elusive. We hypothesized that lower tissue perfusion pressure (TPP), a novel perfusion index representing the difference between..

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Biomarkers for acute kidney injury: a pragmatic approach

Abstract Traditionally, the diagnosis of kidney disease has relied primarily on serum creatinine (SCr). For acute kidney injury (AKI), changes in urine output (UO) have also been recognized as a..

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