Abstract Background and objectives Cardiac surgery associated acute kidney injury can lead to increased morbidity, mortality, and hospitalization. The available risk assessment tools have limited predictive ability. Machine learning has..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious complication, significantly increasing postoperative morbidity and mortality. We aimed to evaluate whether intraoperative peripheral perfusion index (PPI)..
Read MoreAbstract Acute Kidney Injury (AKI) cannot be viewed as a mere complication in critically ill patients who require extracorporeal membrane oxygenation (ECMO). Rather, it is being increasingly recognized as an..
Read MoreAbstract Background Intravenous amino acids (AA) reduce acute kidney injury (AKI) in adult patients undergoing cardiac surgery. Because the optimal duration of AA infusion is unknown, we investigated the effect..
Read MoreAbstract Introduction Monitoring indexed oxygen delivery (DO2i) is recommended during cardiopulmonary bypass (CPB) and a predictor of acute kidney injury (AKI). The use of lean body mass-adjusted blood flow rates..
Read MoreAbstract Background This study aimed to investigate the predictive value of the red cell distribution width-to-platelet ratio (RPR) for cardiac surgery-associated acute kidney injury (CSA-AKI). Methods A retrospective analysis of..
Read MoreAbstract Background Acute kidney injury (AKI) is a common complication after pediatric cardiac surgery using cardiopulmonary bypass (CPB). This study evaluated renal regional oxygen saturation (R-rSO₂), measured via near-infrared spectroscopy..
Read MoreAbstract BACKGROUND: Haptoglobin may reduce hemolysis-induced kidney injury in patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB). Haptoglobin may be given empirically when hemolytic urine is observed, or pre-emptively when..
Read MoreAbstract Background Optimal hemodynamic targets for preventing acute kidney injury (AKI) have remained elusive. We hypothesized that lower tissue perfusion pressure (TPP), a novel perfusion index representing the difference between..
Read MoreAbstract Traditionally, the diagnosis of kidney disease has relied primarily on serum creatinine (SCr). For acute kidney injury (AKI), changes in urine output (UO) have also been recognized as a..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and important complication. The risk factors for CSA-AKI remain poorly described. We aimed to identify risk factors for CSA-AKI..
Read MoreAbstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..
Read MoreAbstract Objectives The Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion (ACTA-PORT) score was originally developed to predict the need for transfusion in cardiac surgery patients. Given the inter-relationship..
Read MoreAbstract Introduction Contrast-induced acute kidney injury (CIAKI) is a common and serious complication of coronary angiography, caused by iodinated contrast agents. It significantly worsens cardiovascular prognosis and increases in-hospital morbidity..
Read MoreAbstract Cardiovascular surgery with cardiopulmonary bypass (CPB) is associated with several potential complications, including the activation of inflammatory and coagulation pathways, which may lead to acute kidney injury (AKI). In..
Read MoreAbstract Background: Acute kidney injury (AKI) is a frequent complication of congenital heart surgery with cardiopulmonary bypass (CPB) in pediatric patients, contributing to significant morbidity and mortality. Aim: To determine..
Read MoreAbstract Objective We aimed to develop and evaluate cardiac surgery–associated acute kidney injury (CSA-AKI) machine learning prediction models that included clinical variables, biomarkers, and high-frequency hemodynamic measurements. Design A prospective,..
Read MoreAbstract Acute kidney injury (AKI) affects 40–50% of cardiac surgery patients and is closely linked to renal medullary hypoxia. Although urinary oxygen partial pressure (PuO2) offers real-time insight into renal..
Read MoreAbstract Background This study aimed to develop a data-driven prediction model for cardiac surgery-associated acute kidney injury (CSA-AKI) at the end of surgery using machine learning (ML) algorithms. Methods We..
Read MoreAbstract Acute kidney injury (AKI) is a significant complication following cardiac surgery, affecting 20% to 30% of patients and contributing to increased morbidity and mortality. Cardiac surgery–associated AKI (CSA-AKI) is..
Read MoreAbstract Background Acute Kidney Injury (AKI) is a frequent post-operative complication following cardiac surgery in the clinical setting. Iron metabolism disorders are a key cause of kidney injury during the..
Read MoreAbstract Perioperative acute kidney injury (AKI) is a frequent complication that affects outcomes well beyond the perioperative period. Its mechanisms remain incompletely understood, arising from the interplay of comorbidities, surgical..
Read MoreAbstract Objectives: This study aimed to assess whether continuous furosemide administration during cardiopulmonary bypass (CPB) in minimally invasive cardiac surgery (MICS) reduces the incidence of cardiac surgery-associated acute kidney injury..
Read MoreAbstract Background Acute renal impairment following cardiopulmonary bypass (CPB) is a serious perioperative complication with sustained occurrence. Proactive risk assessment and preventive strategies are crucial for enhancing surgical outcomes. Methods..
Read MoreAbstract Objectives: To derive and externally validate supervised machine learning (ML) models predictive of cardiac surgery-associated acute kidney injury (CS-AKI). Design: Retrospective cohort analysis. Setting: Multicenter (4), cardiac surgical centers..
Read MoreAbstract Objectives To investigate the potential contribution of tissue oxygenation prediction in cardiac surgery–associated acute kidney injury (CSA-AKI) using near-infrared spectroscopy (NIRS) and serum lactate level measurements. Design A retrospective..
Read MoreAbstract Objectives Acute kidney injury (AKI) occurs in 19–42% of patients with cardiac surgery under cardiopulmonary bypass (CPB). Clarifying their landscape of immune cells may help discover the mechanisms and..
Read MoreAbstract OBJECTIVES: Acute kidney injury (AKI) occurs frequently in ICUs and is associated with poor outcomes. However, little is known about AKI in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) for..
Read MoreAbstract Purpose of review Acute kidney injury (AKI) is common in critically ill patients, especially among those with severe and advanced organ failure. The use of extracorporeal support (ECS) is..
Read MoreAbstract Background Acute kidney injury (AKI) is a frequent complication following cardiac surgery involving cardiopulmonary bypass (CPB). This is partly attributable to crystalloid-based priming solutions causing both hemolysis and loss..
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