Abstract Background: Neonates and young infants undergoing cardiac surgery with cardiopulmonary bypass (CPB) are highly vulnerable to pulmonary dysfunction, systemic inflammation, capillary leak, and fluid overload, which may lead to..
Read MoreAbstract Background/Objectives: Postoperative body temperature abnormalities are common yet underrecognized, and their association with acute kidney injury (AKI) remains unclear. In this study, we aimed to identify early postoperative temperature..
Read MoreAbstract Background: Acute kidney injury (AKI) is a critical complication, affecting up to 30% of coronary artery bypass grafting (CABG) patients, and contributing to significant morbidity and mortality. Recent studies indicate..
Read MoreAbstract Objectives Acute kidney injury (AKI) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). This study investigated whether cell-free hemoglobin (CFHb) levels after CPB are associated with..
Read MoreAbstract Background: Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized for life-threatening cardiac and/or respiratory failure refractory to conventional treatment. Acute kidney injury (AKI) and fluid balance disorders commonly occur both..
Read MoreAbstract Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..
Read MoreAbstract Introduction Acute kidney injury (AKI) is a well-known serious complication of cardiopulmonary bypass (CPB) surgery and one of the significant risk factors for mortality, prolonged hospital stay, and additional..
Read MoreAbstract Background and objectives Cardiac surgery associated acute kidney injury can lead to increased morbidity, mortality, and hospitalization. The available risk assessment tools have limited predictive ability. Machine learning has..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious complication, significantly increasing postoperative morbidity and mortality. We aimed to evaluate whether intraoperative peripheral perfusion index (PPI)..
Read MoreAbstract Acute Kidney Injury (AKI) cannot be viewed as a mere complication in critically ill patients who require extracorporeal membrane oxygenation (ECMO). Rather, it is being increasingly recognized as an..
Read MoreAbstract Background Intravenous amino acids (AA) reduce acute kidney injury (AKI) in adult patients undergoing cardiac surgery. Because the optimal duration of AA infusion is unknown, we investigated the effect..
Read MoreAbstract Introduction Monitoring indexed oxygen delivery (DO2i) is recommended during cardiopulmonary bypass (CPB) and a predictor of acute kidney injury (AKI). The use of lean body mass-adjusted blood flow rates..
Read MoreAbstract Background This study aimed to investigate the predictive value of the red cell distribution width-to-platelet ratio (RPR) for cardiac surgery-associated acute kidney injury (CSA-AKI). Methods A retrospective analysis of..
Read MoreAbstract Background Acute kidney injury (AKI) is a common complication after pediatric cardiac surgery using cardiopulmonary bypass (CPB). This study evaluated renal regional oxygen saturation (R-rSO₂), measured via near-infrared spectroscopy..
Read MoreAbstract BACKGROUND: Haptoglobin may reduce hemolysis-induced kidney injury in patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB). Haptoglobin may be given empirically when hemolytic urine is observed, or pre-emptively when..
Read MoreAbstract Background Optimal hemodynamic targets for preventing acute kidney injury (AKI) have remained elusive. We hypothesized that lower tissue perfusion pressure (TPP), a novel perfusion index representing the difference between..
Read MoreAbstract Traditionally, the diagnosis of kidney disease has relied primarily on serum creatinine (SCr). For acute kidney injury (AKI), changes in urine output (UO) have also been recognized as a..
Read MoreAbstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and important complication. The risk factors for CSA-AKI remain poorly described. We aimed to identify risk factors for CSA-AKI..
Read MoreAbstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..
Read MoreAbstract Objectives The Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion (ACTA-PORT) score was originally developed to predict the need for transfusion in cardiac surgery patients. Given the inter-relationship..
Read MoreAbstract Introduction Contrast-induced acute kidney injury (CIAKI) is a common and serious complication of coronary angiography, caused by iodinated contrast agents. It significantly worsens cardiovascular prognosis and increases in-hospital morbidity..
Read MoreAbstract Cardiovascular surgery with cardiopulmonary bypass (CPB) is associated with several potential complications, including the activation of inflammatory and coagulation pathways, which may lead to acute kidney injury (AKI). In..
Read MoreAbstract Background: Acute kidney injury (AKI) is a frequent complication of congenital heart surgery with cardiopulmonary bypass (CPB) in pediatric patients, contributing to significant morbidity and mortality. Aim: To determine..
Read MoreAbstract Objective We aimed to develop and evaluate cardiac surgery–associated acute kidney injury (CSA-AKI) machine learning prediction models that included clinical variables, biomarkers, and high-frequency hemodynamic measurements. Design A prospective,..
Read MoreAbstract Acute kidney injury (AKI) affects 40–50% of cardiac surgery patients and is closely linked to renal medullary hypoxia. Although urinary oxygen partial pressure (PuO2) offers real-time insight into renal..
Read MoreAbstract Background This study aimed to develop a data-driven prediction model for cardiac surgery-associated acute kidney injury (CSA-AKI) at the end of surgery using machine learning (ML) algorithms. Methods We..
Read MoreAbstract Acute kidney injury (AKI) is a significant complication following cardiac surgery, affecting 20% to 30% of patients and contributing to increased morbidity and mortality. Cardiac surgery–associated AKI (CSA-AKI) is..
Read MoreAbstract Background Acute Kidney Injury (AKI) is a frequent post-operative complication following cardiac surgery in the clinical setting. Iron metabolism disorders are a key cause of kidney injury during the..
Read MoreAbstract Perioperative acute kidney injury (AKI) is a frequent complication that affects outcomes well beyond the perioperative period. Its mechanisms remain incompletely understood, arising from the interplay of comorbidities, surgical..
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