Pediatric

Perfusfind S.L.

Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and lung involvement is common. Patients with COVID-19 may progress to acute respiratory distress syndrome (ARDS) for which they may require mechanical ventilation. When conventional ventilation strategies are unable to achieve the desired oxygenation and..

Perfusfind S.L.

Abstract Background The objective of this randomized clinical trial was to investigate the effects of perfusion modalities on cerebral hemodynamics, vital organ injury, quantified by the Pediatric Logistic Organ Dysfunction-2 (PELOD-2) Score, and clinical outcomes in risk-stratified congenital cardiac surgery patients. Methods This randomized clinical trial included 159 consecutive congenital..

Perfusfind S.L.

Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI) is a common and serious postoperative complication of cardiac surgery with cardiopulmonary bypass (CPB) in children. No studies have yet..

Perfusfind S.L.

Abstract OBJECTIVES:  To determine potential risk factors for severe hemolysis during pediatric cardiopulmonary bypass and examine whether supraphysiologic levels of oxygen and cardiopulmonary bypass duration are associated with hemolysis. DESIGN:  Prospective observational study. SETTING:  Cardiac ICU in a university-affiliated children’s hospital. PATIENTS:  Greater than 1 month to less than 18..

Perfusfind S.L.

Abstract Right heart failure (RHF) is a common, yet difficult to manage, complication of severe acute respiratory distress syndrome requiring extracorporeal membrane oxygenation (ECMO) that is associated with increased mortality. Reports of the use of percutaneous mechanical circulatory support devices for concurrent right heart and respiratory failure are limited. This series..

Perfusfind S.L.

Abstract Introduction Propofol infusion syndrome (PRIS) is a rare entity that could lead to profound cardiogenic shock (CS). Mitochondrial toxicity and sympathetic blockade are the mechanisms leading to CS in PRIS. Case report We present a 22-year-old woman who developed refractory CS due to PRIS after aortic valve replacement surgery..

Perfusfind S.L.

- Hemoadsorption with CytoSorb as part of an individualized therapy in critically-ill patients Chair: Manu Malbrain, Leuven, Belgium and Yatin Mehta, Gurgaon, India - How to balance sepsis campaign guidelines and the need for patient tailored care? Axel Nierhaus, Hamburg, Germany - Use of CytoSorb in different pediatric indications –..

Perfusfind S.L.

Abstract   OBJECTIVES Cardiopulmonary bypass generates a systemic inflammatory response. This inflammatory response is reduced if patients are ventilated during bypass, as evidenced by lower levels of postoperative circulating inflammatory mediators. However, this does not appear to make much clinical difference in adults, at least not consistently, but, to our..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenator (ECMO) is effective for maintaining oxygenation and hemodynamic support in patients with post-cardiotomy cardiogenic shock (PCCS). Researchers, led by Ahmed Abdeljawad, sought to compare the effect of early ECMO implantation in emergency patients versus elective patients who developed univentricular or biventricular pump failure. After their trial,..

Perfusfind S.L.

Abstract During the first wave of the COVID-19 pandemic, the European Extracorporeal Life Support Organization (ELSO) established a prospective survey including 52 European neonatal and paediatric centres and reported the use of extracorporeal membrane oxygenation (ECMO) in seven children with acute respiratory distress syndrome (ARDS) related to COVID-19 and paediatric..