Abstract Purpose: Complications associated with use of dual-lumen venovenous extracorporeal membrane oxygenation (VV-ECMO) cannulas are of concern in pediatric patients. While the risk of atrial perforation is believed to be higher with bicaval cannulas, direct comparison of complication rate between atrial and bicaval cannulas has not been conducted in this..
Read MoreAbstract OBJECTIVES To determine the recommended concentrations of cefazolin to be used for antibiotic prophylaxis during paediatric cardiac surgery with extracorporeal circulation (ECC). METHODS Twenty paediatric patients undergoing cardiac surgery with ECC and cefazolin antibiotic prophylaxis were included in the study. Blood samples for measurement of total cefazolin plasma concentration..
Read MoreAbstract Objectives: To describe blood component usage in transfused children with congenital heart disease undergoing cardiopulmonary bypass surgery across perioperative settings and diagnostic categories. Design: Datasets from U.S. hospitals participating in the National Heart, Lung, and Blood Institute Recipient Epidemiology and Donor Evaluation Study-III were analyzed. Setting: Inpatient admissions from..
Read MoreAbstract Objective: This study aims to investigate the effect of optimized ultrafiltration on perioperative electrolytes, acid–base balance, and pulmonary function during cardiopulmonary bypass (CPB) in infants with low body weight (under 10 kg), using traditional balanced ultrafiltration and modified ultrafiltration. Methods: A total of 30 children who underwent surgical correction for congenital..
Read MoreAbstract Introduction Cardiac surgery (CS) in pediatric patients induces an overt oxidative stress (OS) response. Children are particularly vulnerable to OS related injury. The immaturity of their organs and antioxidant systems as well as the induction of OS in cardio-pulmonary bypass (CPB) surgery may have an important impact on outcomes...
Read MoreDonation after Circulatory Death (DCD) is gaining worldwide acceptance as an adjunct to brain death (BD) in transplant surgery. Initially performed for abdominal organs procurement, DCD was then carried out for heart and lung transplants (HT). Most DCD-HT protocols regard their first cases to be performed with both donor and..
Read MoreAbstract Evidence for the use of extracorporeal membrane oxygenation (ECMO) in children with refractory respiratory failure or shock following ingestion or toxin exposure, has been confined to single-center experiences, individual case reports, and extrapolated from adult cohorts; no pediatric multicenter cohorts exist. The objective of this retrospective review of the..
Read MoreAbstract Objectives Recombinant factor VIIa is used off-label for refractory bleeding after cardiac surgery. This study reviewed the indications, usage rates and complications of recombinant factor VIIa. Design Retrospective case control observational study Setting Single quaternary pediatric hospital Participants All children undergoing cardiac surgery with cardiopulmonary bypass over a 3-year..
Read MoreThis case reports on a 17-year-old male patient with a history of fever, dyspnea, diffuse chest and abdominal pain, and generalized rash following COVID-19 molecular diagnosis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/08/CoW_31_2021_E_web_compressed.pdf"]
Read MoreAbstract OBJECTIVES: Neonates with respiratory failure are ideally supported with veno-venous rather than veno-arterial extracorporeal membrane oxygenation due to the reduced rate of neurologic complications. However, the proportion of neonates supported with veno-venous extracorporeal membrane oxygenation is declining. We report multisite veno-venous extracorporeal membrane oxygenation, accessing the neck, returning to..
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