Abstract Objectives: To describe blood component usage in transfused children with congenital heart disease undergoing cardiopulmonary bypass surgery across perioperative settings and diagnostic categories. Design: Datasets from U.S. hospitals participating in the National Heart, Lung, and Blood Institute Recipient Epidemiology and Donor Evaluation Study-III were analyzed. Setting: Inpatient admissions from..
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Abstract Objective: This study aims to investigate the effect of optimized ultrafiltration on perioperative electrolytes, acid–base balance, and pulmonary function during cardiopulmonary bypass (CPB) in infants with low body weight (under 10 kg), using traditional balanced ultrafiltration and modified ultrafiltration. Methods: A total of 30 children who underwent surgical correction for congenital..
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Abstract Introduction Cardiac surgery (CS) in pediatric patients induces an overt oxidative stress (OS) response. Children are particularly vulnerable to OS related injury. The immaturity of their organs and antioxidant systems as well as the induction of OS in cardio-pulmonary bypass (CPB) surgery may have an important impact on outcomes...
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Donation after Circulatory Death (DCD) is gaining worldwide acceptance as an adjunct to brain death (BD) in transplant surgery. Initially performed for abdominal organs procurement, DCD was then carried out for heart and lung transplants (HT). Most DCD-HT protocols regard their first cases to be performed with both donor and..
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Abstract Evidence for the use of extracorporeal membrane oxygenation (ECMO) in children with refractory respiratory failure or shock following ingestion or toxin exposure, has been confined to single-center experiences, individual case reports, and extrapolated from adult cohorts; no pediatric multicenter cohorts exist. The objective of this retrospective review of the..
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Abstract Objectives Recombinant factor VIIa is used off-label for refractory bleeding after cardiac surgery. This study reviewed the indications, usage rates and complications of recombinant factor VIIa. Design Retrospective case control observational study Setting Single quaternary pediatric hospital Participants All children undergoing cardiac surgery with cardiopulmonary bypass over a 3-year..
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This case reports on a 17-year-old male patient with a history of fever, dyspnea, diffuse chest and abdominal pain, and generalized rash following COVID-19 molecular diagnosis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/08/CoW_31_2021_E_web_compressed.pdf"]
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Abstract OBJECTIVES: Neonates with respiratory failure are ideally supported with veno-venous rather than veno-arterial extracorporeal membrane oxygenation due to the reduced rate of neurologic complications. However, the proportion of neonates supported with veno-venous extracorporeal membrane oxygenation is declining. We report multisite veno-venous extracorporeal membrane oxygenation, accessing the neck, returning to..
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Abstract Neonates and children who have survived critical illness severe enough to require extracorporeal membrane oxygenation (ECMO) are at risk for neurologic insults, neurodevelopmental delays, worsening of underlying medical conditions, and development of new medical comorbidities. Structured neurodevelopmental follow-up is recommended for early identification and prompt interventions of any neurodevelopmental..
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Abstract Background Little is known regarding whether hyperoxic reoxygenation was associated with higher risk of cardiovascular disorder following tetralogy of Fallot repair. Methods We performed a nested case–control study among patients aged 1 month–18 years undergoing complete repair of tetralogy of Fallot in 2012–2018. We measured the highest perfusate oxygenation..
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