Pediatric

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Association Between Exogenous Nitric Oxide Given During Cardiopulmonary Bypass and…

Abstract Objective To compare the incidence and severity of acute kidney injury following open heart surgery with cardiopulmonary bypass in children after administration of exogenous nitric oxide. Design Retrospective cohort study. Setting Single institution, university hospital. Participants: All children less than 18 years of age who underwent surgery with cardiopulmonary..

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A pumpless artificial lung without systemic anticoagulation: The Nitric Oxide…

Abstract Background Artificial lungs have the potential to serve as a bridge to transplantation or recovery for children with end-stage lung disease dependent on extracorporeal life support, but such devices currently require systemic anticoagulation. We describe our experience using the novel Nitric Oxide (NO) Surface Anticoagulation (NOSA) system—an NO-releasing circuit..

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Antifibrinolytic Drugs for the Prevention of Bleeding in Pediatric Cardiac…

Abstract BACKGROUND:  Bleeding is one of the commonest complications affecting children undergoing cardiac surgery on cardiopulmonary bypass. Antifibrinolytic drugs are part of a multifaceted approach aimed at reducing bleeding, though sufficiently sized pediatric studies are sparse, and dosing algorithms are heterogeneous. Our objective was to evaluate the efficacy and safety..

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Residual Lesion Diagnostics in Pediatric Postcardiotomy Extracorporeal Membrane Oxygenation and…

Abstract Background: To assess the impact of diagnostic procedures in identifying residual lesions during extracorporeal membrane oxygenation (ECMO) on survival after pediatric cardiac surgery. Methods: Between January 2012 and December 2017, 74 patients required postcardiotomy ECMO. Patients were retrospectively divided into 2 groups: Group I underwent only echocardiography ([echo only]..

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Strategies to Prevent Acute Kidney Injury after Pediatric Cardiac Surgery

Abstract Background and objectives AKI is a common complication after pediatric cardiac surgery and has been associated with higher morbidity and mortality. We aimed to compare the efficacy of available pharmacologic and nonpharmacologic strategies to prevent AKI after pediatric cardiac surgery. Design, setting, participants, & measurements PubMed/MEDLINE, Embase, Cochrane Controlled Trials Register,..

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Bi-Caval Dual Lumen Catheter for Pediatric Patients Undergoing Venovenous Extracorporeal…

Abstract An 11-year-old female patient was admitted to a pediatric intensive care unit for the treatment of acute respiratory distress syndrome (ARDS). She had received peripheral blood stem cell transplantation for prolymphocytic leukemia 3 months prior and then had been diagnosed with pneumocystis carinii pneumonia 5 days prior, during a..

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Interrelations of Intraoperative Changes in Cerebral Tissue Oxygen Saturation with…

Abstract Objectives The monitoring of cerebral tissue oxygen saturation by near-infrared spectroscopy (ScerebO2) is used widely in pediatric cardiac anesthesia. However, little information is available on the effects of changes in perioperative ScerebO2 on brain morphology and neurologic outcome. The primary hypothesis tested in this study was that intraoperative ScerebO2 during the..

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EuroELSO Webinar: Anticoagulation monitoring on ECMO in neonates and children:…

  EuroELSO Webinar on 30 March 2021 Topic: Anticoagulation monitoring on ECMO in neonates and children: moving target - anti Xa over ACT & APTT.   Introduction, moderation & closing Peter Roeleveld, Leiden, Netherlands   Talk 1: Anticoagulation monitoring on ECMO - brief overview of current modalities including viscoelastic coagulation..

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Risk Factors of Venoarterial Extracorporeal Membrane Oxygenation–Related Intracranial Hemorrhage in…

Abstract To analyze the risk factors for intracranial hemorrhage (ICH) in congenital heart disease (CHD) patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO). We performed a retrospective analysis of VA ECMO patients after open heart surgery in Shanghai Children’s Medical Center from February 2017 to December 2018, with a total of 50..

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Routine Neuroimaging. Understanding Brain Injury in Pediatric Extracorporeal Membrane Oxygenation

Abstract Objectives:  This project aims to describe brain injuries on routine neuroimaging in a large single-center neonatal and pediatric cohort supported by extracorporeal membrane oxygenation. The study also aims to examine the association of these injuries with neurocognitive outcomes in survivors and identify laboratory findings associated with neurologic injury. Design: ..

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