Pediatric

Perfusfind S.L.

Abstract Objective:  To describe neurobehavioral outcomes and investigate factors associated with survival and survival with good neurobehavioral outcome 1 year after in-hospital cardiac arrest for children who received extracorporeal cardiopulmonary resuscitation. Design:  Secondary analysis of the Therapeutic Hypothermia after Pediatric Cardiac Arrest In-Hospital trial. Setting:  Thirty-seven PICUs in the United..

Perfusfind S.L.

Abstract Aim Although recent  (CA) trials found no benefits of  versus normothermia , preclinical models suggest earlier timing of hypothermia improves  efficacy. This study investigated whether shorter time to goal temperature was associated with better one-year outcomes in the  After Pediatric Cardiac Arrest Out-of-Hospital Trial. Methods Patients were classified by tertiles of time to attain..

Perfusfind S.L.

Abstract Background There is an increasing number of young adults living with  (CHD). The goal of this study was to ascertain the frequency of  (AKI) as well as the risk factors and outcomes associated with AKI in young adults with CHD after a surgical procedure. Methods This was a single-center  including all patients..

Perfusfind S.L.

Abstract Perfusion strategies for  have direct consequences on pediatric cardiac surgery outcomes. However, inconsistent study results and a lack of uniform evidence-based guidelines for pediatric cardiopulmonary bypass management have led to considerable variability in perfusion practices among, and even within, institutions. Important aspects of cardiopulmonary bypass that can be optimized to..

Perfusfind S.L.

Abstract Objectives Our aim was to describe the pharmacokinetics of cefazolin in paediatric patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) who received cefazolin for peri-operative surgical prophylaxis in addition to having cefazolin added to the CPB circuit priming solution. Secondary aims were to determine the pharmacodynamic exposure associated with..

Perfusfind S.L.

Abstract Pediatric cardiac surgical patients are at particular risk for post-cardiopulmonary bypass hemorrhage. Moreover, both the incidence and volume of  have been associated with increased morbidity in pediatric cardiac patients. Transfusion of red blood cells, platelets, and  is necessary to combat the  associated with  and to treat . We are challenged to apply new pharmacologic, ,..

Perfusfind S.L.

Abstract The objective of this study is to establish reliable markers for mortality in children with refractory cardiogenic shock who underwent extracorporeal membrane oxygenation. A retrospective observational cohort study was performed at academic children’s hospital for forty-three consecutive pediatric patients who required veno-arterial extracorporeal membrane oxygenation (ECMO) support with refractory..

Perfusfind S.L.

OBJECTIVES Cardioplegia is the primary method for myocardial protection during cardiac surgery. We conducted a systematic review of randomized controlled trials of cardioplegia in children to evaluate the current evidence base. METHODS We searched MEDLINE, CENTRAL and LILACS and manually screened retrieved references and systematic reviews to identify all randomized..

Perfusfind S.L.

Abstract Introduction: We have been developing a closed-circuit cardiopulmonary bypass (CPB) system (“Dihead CPB”) for application during coronary artery bypass grafting (CABG) and valve surgery. To strive for minimal hemolysis during Dihead CPB, we compared the hemolysis caused by three different suction systems and performed a clinical study with the..

Perfusfind S.L.

Abstract Aim To assess the use of   (ECPR), compared with manual or mechanical cardiopulmonary resuscitation (CPR), for  (OHCA) and in-hospital cardiac arrest (IHCA) in adults and children. Methods The PRISMA guidelines were followed. We searched Medline, Embase, and Evidence-Based Medicine Reviews for  and  published before May 22, 2018. The population included adult and pediatric..