Tidal volume

Mechanical Ventilation, Respiratory

Revisiting Acute Respiratory Distress Syndrome ventilation management: Time for a paradigm shift focusing on tidal volume

Abstract: Merola and colleagues critically evaluate current Acute Respiratory Distress Syndrome (ARDS) ventilation strategies, emphasizing limitations inherent in universally applying low tidal volume (VT) strategies. They argue for personalized, physiology-driven ventilation approaches that incorporate mechanical power, compliance, and transpulmonary pressures. The authors highlight the complexity and heterogeneity of ARDS, suggesting the inadequacy of global parameters […]

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Miscellaneous, Sepsis

How I personalize fluid therapy in septic shock?

Abstract During septic shock, fluid therapy is aimed at increasing cardiac output and improving tissue oxygenation, but it poses two problems: it has inconsistent and transient efficacy, and it has many well-documented deleterious effects. We suggest that there is a place for its personalization according to the patient characteristics and the clinical situation, at all

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Mechanical Ventilation, Respiratory

Personalized mechanical ventilation in acute respiratory distress syndrome

Abstract A personalized mechanical ventilation approach for patients with adult respiratory distress syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging, and biological phenotypes may improve ventilation practice and outcome. However, additional research is warranted before personalized mechanical ventilation strategies can be applied at the bedside. Ventilatory parameters should be titrated based

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