Thrombocytopenia

Cardiovascular

Thrombocytopenia in the intensive care unit: diagnosis and management

Summary Thrombocytopenia is a common complication among critically ill patients, defined by platelet counts below 150 × 10⁹/L or a relative decrease by more than 30–50%. It significantly impacts patient outcomes due to increased bleeding risks and worse prognoses. The mechanisms underlying thrombocytopenia in the ICU are diverse, involving peripheral consumption, destruction, sequestration, dilution, or […]

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Practical approach to thrombocytopenia in patients with sepsis: a narrative review

Summary of Practical approach to thrombocytopenia in patients with sepsis: a narrative review Abstract: Thrombocytopenia is common in sepsis, with disseminated intravascular coagulation (DIC) being a frequent cause, though thrombotic microangiopathy (TMA)—including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS)—is increasingly recognized. Differentiating DIC from TMA is challenging due to overlapping clinical and laboratory

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