Serum biomarkers of delirium in critical illness: a systematic review of mechanistic and diagnostic evidence
Serum Biomarkers of Delirium in Critical Illness Abstract: Delirium is a frequent and serious complication of critical illness, with up to 80% of ventilated ICU patients affected. This systematic review synthesized evidence from 28 studies assessing 54 serum biomarkers related to delirium, grouped into six mechanistic categories: CNS injury, immune activation, hormonal dysregulation, neurotransmission, coagulation, […]