Toward optimal mechanical ventilation of the injured lung: the role of expiratory duration
Abstract This perspective challenges one of the most fundamental assumptions in ARDS ventilation: that only inspiratory forces (tidal volume, driving pressure, plateau pressure, mechanical power) shape lung injury. The authors argue that expiratory time—specifically, the rate of lung emptying—is an overlooked determinant of stress and strain. In injured lungs with low compliance and heterogeneous time […]