Regional venous-to-arterial carbon dioxide pressure and content differences during endotoxemic shock: influence of hydrogen ion accumulation vs…..
Abstract: This study investigated whether discrepancies between venous-to-arterial carbon dioxide pressure (ΔPCO₂) and content differences (ΔCCO₂) during endotoxemic shock are primarily influenced by hydrogen ion accumulation (acidosis) or hemoglobin oxygen saturation (Haldane effect). Using a porcine endotoxemia model, researchers induced and resuscitated shock with fluids and norepinephrine, measuring systemic and mesenteric CO₂ parameters. Key Insights: […]