April 2025

Mechanical Ventilation

Ten rules for optimizing ventilatory settings and targets in post-cardiac arrest patients

Summary of “Ten rules for optimizing ventilatory settings and targets in post-cardiac arrest patients” Abstract This review proposes ten evidence-based rules to optimize mechanical ventilation in post-cardiac arrest (CA) patients. It focuses on lung-protective strategies, the balance of ventilator settings, and their influence on systemic physiology—especially cerebral function. Emphasizing parameters such as tidal volume, plateau […]

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Pulmonary

Advances in acute respiratory distress syndrome: focusing on heterogeneity, pathophysiology, and therapeutic strategies

Summary of “Advances in acute respiratory distress syndrome: focusing on heterogeneity, pathophysiology, and therapeutic strategies” Abstract This review addresses the growing complexity and heterogeneity of acute respiratory distress syndrome (ARDS), emphasizing its diverse pathophysiology, evolving clinical presentations, and variable treatment responses. Despite decades of study, ARDS remains a major cause of ICU mortality. The article

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Pulmonary

Acute Respiratory Distress Syndrome and Fluid Management: Finding the Perfect Balance

Summary of “Acute Respiratory Distress Syndrome and Fluid Management: Finding the Perfect Balance” (J. Clin. Med. 2025, 14, 2067) Abstract Acute Respiratory Distress Syndrome (ARDS) is characterized by alveolar epithelial injury leading to capillary leak and alveolar flooding. While fluid therapy is often essential in early resuscitation, excessive fluid administration may exacerbate pulmonary edema, impair

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Cardiovascular, Pulmonary

Navigating Heart–Lung Interactions in Mechanical Ventilation: Pathophysiology, Diagnosis, and Advanced Management Strategies in ARDS and Beyond

Summary of “Navigating Heart–Lung Interactions in Mechanical Ventilation: Pathophysiology, Diagnosis, and Advanced Management Strategies in Acute Respiratory Distress Syndrome and Beyond” Abstract: This article explores the intricate cardiopulmonary dynamics encountered in critically ill patients undergoing mechanical ventilation. It emphasizes the importance of understanding heart–lung interactions, particularly the vulnerability of the right ventricle (RV) under mechanical

Navigating Heart–Lung Interactions in Mechanical Ventilation: Pathophysiology, Diagnosis, and Advanced Management Strategies in ARDS and Beyond Read Post »

Mechanical Ventilation

First Stabilize and then Gradually Recruit: A Paradigm Shift in Protective Mechanical Ventilation for Acute Lung Injury

Summary of “First Stabilize and then Gradually Recruit: A Paradigm Shift in Protective Mechanical Ventilation for Acute Lung Injury” Citation: Nieman GF, Kaczka DW, Andrews PL, et al. J Clin Med. 2023;12(14):4633. doi:10.3390/jcm12144633 Abstract The article introduces a new paradigm in mechanical ventilation for acute lung injury, emphasizing a “Stabilize Lung Approach” (SLA) over traditional

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Mechanical Ventilation

Mechanical Power in Pressure-Controlled Ventilation: A Simple and Reliable Bedside Method

Summary of Mechanical Power in Pressure-Controlled Ventilation: A Simple and Reliable Bedside Method Snoep JWM, Rietveld PJ, van der Velde-Quist F, de Jonge E, Schoe A. Crit Care Explor. 2025. Abstract This study presents a newly proposed equation for calculating mechanical power (MP) in pressure-controlled ventilation (PCV) that is both simple and accurate for bedside

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Mechanical Power in Pressure-Controlled Ventilation: A Simple and Reliable Bedside Method Read Post »

Cardiovascular

Association between mean hemodynamic variables during the first 24 h and outcomes in cardiogenic shock: identification of clinically relevant thresholds

Summary of “Association between mean hemodynamic variables during the first 24 h and outcomes in cardiogenic shock: identification of clinically relevant thresholds” Abstract: This study investigated the association between mean hemodynamic variables within the first 24 hours and outcomes in patients with cardiogenic shock (CS). Using data from two prospective cohorts (OptimaCC and MicroShock), researchers

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Association between mean hemodynamic variables during the first 24 h and outcomes in cardiogenic shock: identification of clinically relevant thresholds Read Post »

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