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The effects of mechanical ventilation during v-a ecmo support: a systematic review

Abstract Background Mechanical ventilation is routinely used during veno-arterial extracorporeal membrane oxygenation (V-A ECMO), but its role in influencing hemodynamics and supporting cardiac recovery remains poorly understood. This systematic review..

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Novel Extracorporeal Life Support System to Mitigate Ischemia-Reperfusion Injury During Prolonged Aortic and Inferior Vena Caval Occlusion

Abstract Extracorporeal membrane oxygenation (ECMO) and endovascular balloon occlusion of the aorta (REBOA) have been reported to manage hemodynamics and reduce blood loss and transfusion requirements during high-risk abdominal surgeries...

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Diagnostic Imaging Challenges During Extracorporeal Membrane Oxygenation

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical life support therapy for severe cardiac and respiratory failure, but it is associated with thromboembolic, hemorrhagic, and neurological complications. Diagnostic imaging..

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Anticoagulation Strategies in Adults Undergoing Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for patients with severe cardiac or respiratory failure, but it is associated with a high risk of thrombotic and bleeding..

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Costs and complications of extracorporeal membrane oxygenation therapy in Australia and New Zealand

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving form of cardiopulmonary support for patients with severe refractory cardiopulmonary disease. It is a resource-intensive intervention requiring specialised equipment and personnel,..

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Comparison of Left Ventricular Pressure-Volume Loops With Veno-Arterial Extracorporeal Membrane Oxygenator Support: In Vitro Investigation

Abstract Background The hemodynamic consequence of increasing veno-arterial extracorporeal membrane oxygenator (V-A ECMO) flow on left ventricular (LV) loading is controversial, with in vivo studies reporting conflicting results on left ventricular..

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Clinical Outcomes of Different Heparin Anticoagulation Monitoring Targets in Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis

Abstract Objectives This systematic review and meta-analysis aimed to evaluate clinical outcomes associated with different systemic heparin protocols (conservative v standard intensity) during extracorporeal membrane oxygenation (ECMO) support. Included studies comprised both..

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Safety and efficacy of OASSIST ECMO system: A first-in-human, multi-center, clinical trial

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) provides respiratory and circulatory support in patients with severe cardiorespiratory failure. As ECMO technology advances, portability has become an important design consideration for transport..

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Hypothermia exacerbates kidney injury during extracorporeal cardiopulmonary resuscitation

Abstract Objective Kidney injury is one of the most common complications of extracorporeal cardiopulmonary resuscitation (ECPR), yet the renoprotective effects of temperature management during ECPR remain inconclusive. This study aimed..

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Rescue strategies combining ultra-protective ventilation and veno-venous ECMO in a patient with near-drowning-related severe ARDS: a case report and literature…

Abstract Background Drowning can lead to acute respiratory distress syndrome (ARDS), which is associated with high mortality and poses substantial clinical management challenges. Ultra-protective ventilation strategy combined with veno-venous extracorporeal..

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Improving outcomes of patients with venovenous extracorporeal membrane oxygenation

Abstract Venovenous extracorporeal membrane oxygenation (VV ECMO) is a potentially lifesaving yet resource-intensive organ support option for patients with very severe respiratory failure refractory to optimized conventional management. Mortality remains..

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Artificial intelligence-guided tools in adult ECMO: Current advancements, emerging Trends and future directions

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) provides life support for patients with refractory cardiac or respiratory failure. The complexity of ECMO management and associated mortality necessitates high-accuracy clinical decision-making systems...

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Proactive versus resuscitative extracorporeal membrane oxygenation for low cardiac output syndrome after cardiac surgery

Abstract Objectives We sought to evaluate extracorporeal membrane oxygenation (ECMO) use for low cardiac output syndrome (LCOS) after congenital heart surgery. Our primary aims were (1) to compare hospital mortality..

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Surgical technique of donation after circulatory death heart procurement using direct procurement and hypothermic oxygenated perfusion preservation

Abstract Introduction Donation after circulatory death (DCD) has re-emerged as a means of expanding the donor heart pool. Current clinical practice relies mainly on direct procurement followed by normothermic machine..

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Hemolysis testing in circulatory support pumps: Standards, mock loops, and pulsatility

Abstract Hemolysis evaluation is central to the safety assessment of blood pumps and extracorporeal circulatory support, yet clinically relevant hemolysis continues to occur despite widespread use of standardized in vitro..

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Vascular implications of non-pulsatile flow extracorporeal life support

Abstract Extracorporeal life support has become a widely integrated tool in treating refractor cardiopulmonary failure. Under normal physiologic conditions, arterial blood flow is inherently pulsatile, and cyclic shear stress plays..

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Long-term quality of life and functional outcomes in extracorporeal membrane oxygenation survivors

Abstract Extracorporeal membrane oxygenation (ECMO) has become an increasingly vital intervention for patients with severe cardiac and respiratory failure, significantly improving short-term survival rates. However, there is growing recognition of..

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ELSO-score: A practical pre-ECMO risk model for predicting in-hospital mortality in patients receiving VA-ECMO

Abstract Background Despite advancements in management strategies, patients with refractory cardiogenic shock (CS) have high mortality. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly utilized as temporary mechanical support in these..

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How to optimize brain perfusion and prevent cerebral complications during extracorporeal life support

Abstract Extracorporeal life support (ECLS) is increasingly used to rescue patients with refractory respiratory failure, cardiogenic shock and/or cardiac arrest. Acute brain injury during ECLS is common and associated with..

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Prophylactic temporary mechanical circulatory support: The new paradigm in cardiac surgery

Abstract Background Post-cardiotomy cardiogenic shock (PCCS) remains one of the most lethal complications of cardiac surgery, with high in-hospital mortality despite major improvements in operative techniques, and intensive care management...

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A Novel Trans-Septal Cannula for Wearable Extracorporeal Membrane Oxygenation: In Vitro Hemodynamic Evaluation and Placement Feasibility

Abstract Extracorporeal membrane oxygenation (ECMO) supports patients with end-stage heart and lung disease awaiting transplantation. In pulmonary hypertension, veno-arterial ECMO (VA-ECMO) is common but linked to vascular complications and limited..

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Hemodynamic monitoring during veno-venous extracorporeal membrane oxygenation: A scoping review

Abstract Background In adult patients receiving veno-venous Extracorporeal Membrane Oxygenation (VV ECMO), cardiovascular performance plays a critical role in determining oxygen delivery, organ perfusion and safe titration of extracorporeal support...

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ECMO transports perspectives on organization and patient management: A narrative review

Abstract Background Extracorporeal membrane oxygenation (ECMO) is an established life support technique for refractory acute cardiorespiratory failure in children and adult patients. However, ECMO support is provided only by specialized..

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Use of extracorporeal circulation in multidisciplinary approach and replantation strategies for traumatic limb amputations: A case report

Abstract Background Traumatic major limb amputations require urgent intervention to prevent irreversible tissue necrosis and life-threatening systemic complications due to warm ischemia. We aim to demonstrate the efficacy of extracorporeal..

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Extracorporeal life support in lung transplantation with dual-lumen cannulas: A systematic review

Abstract Background Refractory end-stage lung failure may benefit from extracorporeal life support (ECLS) as a bridge to lung transplantation. Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is indicated in patients who..

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Changes in hemodynamics, cardiac energetics, and cell signaling pathways induced by veno-arterial extracorporeal membrane oxygenation with or without left ventricular…

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly used in refractory cardiogenic shock (CS) but may exacerbate left ventricular (LV) loading conditions and impair cardiac energetics. Adjunctive LV..

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Impact of eosinophil levels on postoperative clinical outcomes in patients undergoing extracorporeal circulation: a retrospective cohort study

Abstract Background Extracorporeal circulation (ECC) is an essential operation in many cardiac surgeries, but contact between blood and connecting tubes can activate inflammatory factors and adversely affect complement. Previous studies..

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Development of a Plasma Free Hemoglobin-Adsorbing Device for Extracorporeal Therapies

Abstract In extracorporeal therapies such as cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO), the transport of blood through artificial circulation frequently results in the rupture of erythrocytes, releasing hemoglobin..

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Preoperative Platelet Count Predicts In-Hospital Mortality in Patients Supported With Venoarterial Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Cohort Study

Abstract Objectives To determine whether preoperative platelet (PLT) count independently predicts in-hospital mortality in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). Design Secondary analysis of a prospectively maintained institutional registry...

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Impact of combined ECMO - CRRT support on patient outcomes and risk factors: a multicenter retrospective study

Abstract Objective This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its..

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