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Death and new disability following bleeding complications during venoarterial extracorporeal membrane oxygenation. A prospective cohort study from the EXCEL registry

Abstract Introduction Bleeding events are common during the provision of Venoarterial ECMO (VA ECMO). Previous observational has suggested that these bleeding events are associated with an increased risk of in-hospital..

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Indications and outcomes of extracorporeal life support in trauma patients

Abstract BACKGROUND  The use of extracorporeal life support (ECLS) in the trauma population remains controversial and has been reported only in small cohort studies. Recent ECLS technical advances have increased..

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The Impact of Venovenous Extracorporeal Membrane Oxygenation Cannulation Configuration on Hemodynamic Characteristics and Risks of Hemolysis

Abstract Objective To investigate the impact of veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannula configuration and ECMO blood flow on intravascular hemodynamic environment, oxygen saturation, hemolysis, and thrombotic risk under varying..

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Between Hope and Harm: A Meta-Synthesis of Family Decision-Making Agonies in ECMO Initiation Crossroads

Abstract Background Family members making decisions about ECMO initiation face high-stakes uncertainty, emotional stress and cultural–ethical dilemmas. However, existing research lacks a synthesised understanding of these decision-making experiences across contexts...

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Ethical Dilemmas Surrounding ECMO Withdrawal: A Qualitative Empirical Study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical, life-sustaining intervention often described as ‘a bridge to nowhere’ due to its transient nature and the ethical complexities it entails. This..

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Plasma Exchange in the Setting of Immune-Mediated Multiple Organ Failure in the Cardiac ICU During ECMO: A Case Series

Abstract Extracorporeal membrane oxygenation (ECMO) is a last resort treatment for children with cardio-respiratory failure. Some of these patients will develop thrombocytopenia-associated multiple organ failure (TAMOF), which is sometimes managed..

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Differential Hypoxemia During Veno-Arterial Extracorporeal Organ Support: Its Impact on Mortality and Different Treatment Strategies

Abstract Objectives Extracorporeal Life Support (ECLS) has evolved into an established treatment for severe cardiogenic shock. As most patients have residual antegrade left ventricular output toward the descending aorta that..

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Clinical study of area-decreasing technique and conventional post-closure technique for V-A ECMO weaning application: study protocol of a randomised controlled…

Abstract Introduction Two techniques are commonly used for the femoral artery puncture closure during decannulation in venoarterial extracorporeal membrane oxygenation (V-A ECMO): the conventional post-closure technique and the small-sheath technique, also..

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Association between parenteral nutrition and extracorporeal membrane oxygenation circuit dysfunction in critically ill adults requiring extracorporeal life support: A retrospective…

Abstract Background Extracorporeal life support is influenced by membrane integrity and nutrition. The impact of parenteral nutrition with lipid injectable emulsions on membrane function remains uncertain. Methods This retrospective cohort..

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ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part I: Preoperative Considerations

Abstract The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no..

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Safely combining renal replacement therapy and extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is an extracorporeal technique used in acute circulatory and respiratory failures refractory to conventional therapies. ECMO patients are at risk of developing severe acute kidney..

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Practice of Apnea Testing and Determination of Brain Death During Extracorporeal Membrane Oxygenation: A Multicenter Retrospective Analysis

Abstract To explore whether reducing airflow and maintaining blood flow can improve the success rate of the apnea test (AT) and whether two auxiliary test strategies can improve the completion..

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Outcomes of central versus peripheral arterial cannulation for intraoperative extracorporeal membrane oxygenation support in lung transplantation

Abstract Background Intraoperative venoarterial extracorporeal membrane oxygenation (VA ECMO) is becoming the most common mode of extracorporeal life support (ECLS) in lung transplantation (LTx). We compared rates of primary graft..

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Development of nursing quality evaluation indicators for extracorporeal membrane oxygenation based on Donabedian theory: A Delphi study

Abstract Extracorporeal membrane oxygenation (ECMO) serves as a vital therapy for refractory severe respiratory and circulatory failure. With its expanding application in China and the heightened demand for high-quality medical..

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Extracorporeal Membrane Oxygenation in Liver Transplantation: Mayo Clinic Experience—A Case Series and Review

Abstract Extracorporeal membrane oxygenation (ECMO) use during liver transplantation is a complex and evolving aspect of critical care. This retrospective analysis presents the largest North American case series to date,..

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Silk-based multilayer coatings for anticoagulation and durability improvement in ECMO hollow fiber membranes

Abstract In clinical extracorporeal membrane oxygenation (ECMO), prolonged blood residence time in oxygenators can lead to thrombus formation and complications. Heparin-based bioactive coatings are commonly used for anticoagulation, but prolonged..

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Development of ECMO training program for ICU nurses knowledge gain and self-efficacy outcomes assessment: quasi-experimental evaluation

Abstract Aim and objectives To develop an extracorporeal membrane oxygenation (ECMO) training program for intensive care unit (ICU) nurses and assessing the impact of the training on the knowledge and..

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Using an intermittent flow (“clamp and flash”) method to assess the readiness to wean from VA ECMO in adult and…

Abstract Background: The use of VA extracorporeal membrane oxygenation (ECMO) for cardiac recovery is widely adopted, with extensive publications on assessing readiness to wean from VA ECMO. Techniques to reduce..

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Venovenous Extracorporeal Membrane Oxygenation Outcomes in Cirrhosis: An Extracorporeal Life Support Organization Registry Study

Abstract Cirrhosis was previously listed in Extracorporeal Life Support Organization (ELSO) guidelines as an absolute contraindication for venovenous extracorporeal membrane oxygenation (VV ECMO) and has since been removed. Minimal data..

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Evaluation of Cerebral Blood Pressure During Normothermic Regional Perfusion

Abstract Normothermic regional perfusion (NRP) is an effective method for recovering donation after circulatory death (DCD) organs. However, concerns remain that NRP may allow unintended cerebral perfusion despite clamping of..

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Hemodynamics in femoro-femoral venovenous extracorporeal membrane oxygenation using large eddy simulations

Abstract Venovenous extracorporeal membrane oxygenation (ECMO) is used for support in refractory severe respiratory failure. Venous drainage and return are accomplished through cannulation of patient’s major veins, typically on the..

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Understanding the Outcomes of Extracorporeal Membrane Oxygen Support in Patients With Sickle Cell Trait

Abstract The impact of common hemoglobinopathies, such as sickle cell trait (SCT), on outcomes in adults requiring extracorporeal membrane oxygenation (ECMO) remains understudied. Extracorporeal Life Support Organization registry data was..

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Buttock ischemia in adults with femoral venoarterial-extracorporeal membranoxygenation – A single center experience

Abstract Introduction Femoral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is used as an ultima ratio to maintain circulation in patients with refractory cardiorespiratory failure, but is also associated with vascular and..

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A silicon membrane microfluidic oxygenator for use as an artificial placenta with minimal anticoagulation

Abstract Extreme prematurity carries a high burden of morbidity and mortality. The artificial placenta is an emerging therapy that has the potential to improve outcomes in these patients. However, current..

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Complications of microaxial flow pump and VA-ECMO in infarct-related cardiogenic shock: Insights from the Netherlands heart registration

Abstract Background Active mechanical circulatory support (MCS) is associated with high complication rates. Reducing device-related complications may improve outcomes in patients with infarct-related cardiogenic shock (AMI-CS). This study aims to..

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Baseline characteristics and in-hospital mortality predictors in female patients on venovenous extracorporeal membrane oxygenation: Impact of pregnancy

Abstract Background Venovenous extracorporeal membrane oxygenation (VV-ECMO) is often used for lung rest in critically ill patients, including pregnant patients. Objectives We aimed to determine how pregnant and non-pregnant patients..

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Predicting Successful Weaning from Veno-Arterial ECMO Using Machine Learning

Abstract Extracorporeal Membrane Oxygenation (ECMO) is a life-saving cardiopulmonary support for patients with acute heart failure. However, the process of weaning from veno-arterial (V-A) ECMO remains complex and risky. We..

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Simulation-Based Education for Extracorporeal Membrane Oxygenation and Strategies for Implementation

Abstract Simulation-based education (SBE) in health care is expanding in both scope and relevance. As on-the-job training is challenging in extracorporeal membrane oxygenation (ECMO), SBE features strongly in its curricula,..

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ELSO 2025 Narrative Guideline on the Use of ECMO for Accidental Hypothermia

Background Accidental hypothermia (AH) can be caused by exposure to cold weather conditions, immersion in water, avalanche burial in snow, or indoors, mostly affecting elderly patients with multiple comorbidities., There are..

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Clinical outcomes of levosimendan administration in veno-arterial extracorporeal membrane oxygenation: a meta-analysis

Abstract Objectives To evaluate the effectiveness of levosimendan in promoting weaning from veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with refractory cardiogenic shock through a meta-analysis of clinical trials. Design Systematic review..

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