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Five Years After Extracorporeal Membrane Oxygenation: A Prospective Cohort Study of Health-Related Quality of Life and Patient Outcomes

Abstract Objectives:  To report on 5-year survival, health-related quality of life (HRQoL), and occupational status of patients with respiratory or cardiac failure, who were supported with extracorporeal membrane oxygenation (ECMO)...

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Construction of a nomogram model for individualized prediction of extracorporeal membrane oxygenation weaning outcomes in cardiogenic shock

Abstract Objective To construct a nomogram prediction model for death in patients with cardiogenic shock after extracorporeal membrane oxygenation (ECMO) weaning. Methods Totally 210 patients with cardiogenic shock treated with..

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Predictivity of Each Readiness-to-Explant Criterion for Successful Venoarterial Extracorporeal Membrane Oxygenation Explantation

Abstract Background: The use of temporary mechanical circulatory support (tMCS) has revolutionized the management of cardiogenic shock (CS). However, standardized readiness-to-explant criteria for venoarterial extracorporeal membrane oxygenation (VA-ECMO) have not been..

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Extracorporeal Membrane Oxygenation in Adults with Congenital Heart Disease: Considerations, Cannulation and Challenges for Complex Cardiac Anomalies

Abstract As survival among patients with congenital heart disease (CHD) continues to improve, the population of adults with CHD (ACHD) is rapidly growing. These patients often present with complex anatomy,..

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Novel heat exchanger in extracorporeal circuit: technical and biological feasibility

Abstract To evaluate a novel anticoagulation strategy in an extracorporeal circuit, we introduce a device that induces local hypothermia as blood flows through the circuit. Using a pig model, we..

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Cardiovascular Physiology During Mechanical Circulatory Support: Implications for Management and Monitoring

Abstract Background/Objectives: Mechanical circulatory support (MCS) is increasingly utilized for the management of acute decompensated heart failure (HF) and cardiogenic shock (CS). The primary goals of MCS are to restore systemic..

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A nitric oxide-releasing organic selenium-grafted phosphorylcholine coating for thrombosis and inflammation prevention in extracorporeal membrane oxygenation

Abstract Thrombosis and inflammation represent major challenges limiting the functionality of asymmetric poly(4-methyl-1-pentene) (PMP) hollow fiber membranes in extracorporeal membrane oxygenation (ECMO) systems. Moreover, the interplay between these two pathological..

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Flow monitoring of venovenous and venoarterial ECMO to detect circuit obstructions using hemodynamic modeling

Abstract Introduction Current extracorporeal membrane oxygenation (ECMO) monitoring methods for circuit obstructions have limitations. In this study, we test the hypothesis that changes in flow in a pre-existing shunt tubing..

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Impact of early PaCO2 and pH fluctuations on neurological outcomes in ARDS patients receiving VV ECMO: a retrospective cohort study…

Abstract Background Neurological complications significantly contributed to mortality in patients with acute respiratory distress syndrome (ARDS) supported by venovenous extracorporeal membrane oxygenation (VV ECMO). Early fluctuations in arterial partial pressure..

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Trends and outcomes of cardiac arrest and extracorporeal membrane oxygenation during the COVID-19 pandemic in the United States

Abstract Background The COVID-19 Pandemic challenged the healthcare system worldwide, but its effect on outcomes of cardiac arrest (CA) and extracorporeal membrane oxygenation (ECMO) use are understudied. We examined trends..

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Early Exposure to Arterial Hyperoxia During Extracorporeal Membrane Oxygenator Support and Acute Brain Injury and Mortality in Patients With Cardiogenic…

Abstract BACKGROUND:  Patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) are frequently managed with varying degrees of hyperoxia. Existing data suggest that higher levels of Pao2 correlate with worsened outcome in patients..

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“Safety of ECMO Cannulation: Organization and Standardized Training Matters”

Abstract We appreciate the insightful remarks by Sin et al regarding our systematic review and meta-analysis on extracorporeal membrane oxygenation (ECMO) cannulation by intensivists. Their comments highlight important considerations for..

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Novel use of negative pressure ventilation for weaning of venovenous extracorporeal membrane oxygenation

Abstract Negative pressure ventilation (NPV) has been used to assist patients with respiratory failure. Venovenous extracorporeal membrane oxygenation (V-V ECMO) supports patients with acute lung injury who do not respond..

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Death and new disability following bleeding complications during venoarterial extracorporeal membrane oxygenation. A prospective cohort study from the EXCEL registry

Abstract Introduction Bleeding events are common during the provision of Venoarterial ECMO (VA ECMO). Previous observational has suggested that these bleeding events are associated with an increased risk of in-hospital..

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Indications and outcomes of extracorporeal life support in trauma patients

Abstract BACKGROUND  The use of extracorporeal life support (ECLS) in the trauma population remains controversial and has been reported only in small cohort studies. Recent ECLS technical advances have increased..

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The Impact of Venovenous Extracorporeal Membrane Oxygenation Cannulation Configuration on Hemodynamic Characteristics and Risks of Hemolysis

Abstract Objective To investigate the impact of veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannula configuration and ECMO blood flow on intravascular hemodynamic environment, oxygen saturation, hemolysis, and thrombotic risk under varying..

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Between Hope and Harm: A Meta-Synthesis of Family Decision-Making Agonies in ECMO Initiation Crossroads

Abstract Background Family members making decisions about ECMO initiation face high-stakes uncertainty, emotional stress and cultural–ethical dilemmas. However, existing research lacks a synthesised understanding of these decision-making experiences across contexts...

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Ethical Dilemmas Surrounding ECMO Withdrawal: A Qualitative Empirical Study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical, life-sustaining intervention often described as ‘a bridge to nowhere’ due to its transient nature and the ethical complexities it entails. This..

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Plasma Exchange in the Setting of Immune-Mediated Multiple Organ Failure in the Cardiac ICU During ECMO: A Case Series

Abstract Extracorporeal membrane oxygenation (ECMO) is a last resort treatment for children with cardio-respiratory failure. Some of these patients will develop thrombocytopenia-associated multiple organ failure (TAMOF), which is sometimes managed..

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Differential Hypoxemia During Veno-Arterial Extracorporeal Organ Support: Its Impact on Mortality and Different Treatment Strategies

Abstract Objectives Extracorporeal Life Support (ECLS) has evolved into an established treatment for severe cardiogenic shock. As most patients have residual antegrade left ventricular output toward the descending aorta that..

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Clinical study of area-decreasing technique and conventional post-closure technique for V-A ECMO weaning application: study protocol of a randomised controlled…

Abstract Introduction Two techniques are commonly used for the femoral artery puncture closure during decannulation in venoarterial extracorporeal membrane oxygenation (V-A ECMO): the conventional post-closure technique and the small-sheath technique, also..

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Association between parenteral nutrition and extracorporeal membrane oxygenation circuit dysfunction in critically ill adults requiring extracorporeal life support: A retrospective…

Abstract Background Extracorporeal life support is influenced by membrane integrity and nutrition. The impact of parenteral nutrition with lipid injectable emulsions on membrane function remains uncertain. Methods This retrospective cohort..

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ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part I: Preoperative Considerations

Abstract The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no..

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Safely combining renal replacement therapy and extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is an extracorporeal technique used in acute circulatory and respiratory failures refractory to conventional therapies. ECMO patients are at risk of developing severe acute kidney..

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Practice of Apnea Testing and Determination of Brain Death During Extracorporeal Membrane Oxygenation: A Multicenter Retrospective Analysis

Abstract To explore whether reducing airflow and maintaining blood flow can improve the success rate of the apnea test (AT) and whether two auxiliary test strategies can improve the completion..

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Outcomes of central versus peripheral arterial cannulation for intraoperative extracorporeal membrane oxygenation support in lung transplantation

Abstract Background Intraoperative venoarterial extracorporeal membrane oxygenation (VA ECMO) is becoming the most common mode of extracorporeal life support (ECLS) in lung transplantation (LTx). We compared rates of primary graft..

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Development of nursing quality evaluation indicators for extracorporeal membrane oxygenation based on Donabedian theory: A Delphi study

Abstract Extracorporeal membrane oxygenation (ECMO) serves as a vital therapy for refractory severe respiratory and circulatory failure. With its expanding application in China and the heightened demand for high-quality medical..

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Extracorporeal Membrane Oxygenation in Liver Transplantation: Mayo Clinic Experience—A Case Series and Review

Abstract Extracorporeal membrane oxygenation (ECMO) use during liver transplantation is a complex and evolving aspect of critical care. This retrospective analysis presents the largest North American case series to date,..

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Silk-based multilayer coatings for anticoagulation and durability improvement in ECMO hollow fiber membranes

Abstract In clinical extracorporeal membrane oxygenation (ECMO), prolonged blood residence time in oxygenators can lead to thrombus formation and complications. Heparin-based bioactive coatings are commonly used for anticoagulation, but prolonged..

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Development of ECMO training program for ICU nurses knowledge gain and self-efficacy outcomes assessment: quasi-experimental evaluation

Abstract Aim and objectives To develop an extracorporeal membrane oxygenation (ECMO) training program for intensive care unit (ICU) nurses and assessing the impact of the training on the knowledge and..

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