Abstract Background The nadir oxygen delivery index (DO2i) during cardiopulmonary bypass (CPB) is reportedly associated with acute kidney injury (AKI) in patients undergoing cardiac surgery. However, there are few reports..
Lee masAbstract OBJECTIVES Peripheral cannula selection in minimally invasive cardiac surgery (MICS) is crucial, as venous drainage limitations during cardiopulmonary bypass (CPB can impair end-organ perfusion and overall outcomes. This study..
Lee masAbstract BACKGROUND: Prior studies identified thresholds for mean arterial pressure (MAP <65 mm Hg) and central venous pressure (CVP >12 mm Hg) beyond which risk for cardiac surgery-associated acute kidney..
Lee masAbstract Background Current indicators for monitoring intraoperative organ function remain predominantly indirect, delayed and non-specific, particularly in paediatric populations undergoing congenital heart surgery, where multifactorial influences further complicate functional assessments. Emerging..
Lee masAbstract Objective Acute kidney injury (AKI) affects approximately 30% of patients undergoing cardiac surgery with conventional non-pulsatile cardiopulmonary bypass (CPB). Pulsatile flow has long been proposed for mitigating this complication...
Lee masAbstract OBJECTIVES Acute kidney injury (AKI) is a common consequence of surgical repair of the thoraco-abdominal aorta (TAA). Perfusion techniques aim to facilitate renal protection through oxygenation or hypothermia. This..
Lee masAbstract Purpose Cardiac surgery associated acute kidney injury (CSA-AKI) is a frequent and severe complication. Goal Directed Perfusion (GDP) during cardiopulmonary bypass (CPB) has been developed to reduce post-operative complications,..
Lee masAbstract Acute Kidney Injury (AKI) is a common complication after cardiac surgery affecting up to 40% leading to increased morbidity and mortality. To date, there is no specific treatment for..
Lee masAbstract Heart failure remains a leading cause of morbidity and mortality globally, particularly among individuals with advanced forms of the disease. This study introduces a groundbreaking hydromagnetic artificial heart..
Lee masAbstract The use of extracorporeal membrane oxygenation has been increasing over time, in part due to the COVID-19 pandemic. Whilst lifesaving, complications that must be managed are also associated with..
Lee masAbstract Objective Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used to rescue patients in cardiac arrest. However, minimal data guide candidacy decisions, and centers must develop their own initiation criteria, raising..
Lee masAbstract Background: Postoperative Acute kidney injury (AKI) is a significant concern for cardiac surgery patients with chronic kidney disease (CKD). Effective pharmacological interventions to mitigate these risks are urgently needed...
Lee masAbstract In recent decades, multiple efforts have been made to reduce population exposure to cigarettes, given that smoking is responsible for thousands of deaths annually. These actions have been effective,..
Lee masAbstract Perioperative pulmonary arterial hypertension (PAH) is a common complication of chest surgery with cardiopulmonary bypass (CPB) and its etiology is multifactorial. Patients undergoing this surgery often have underlying conditions,..
Lee masAbstract Objectives To study the association between bleeding and acute kidney injury (AKI). Design Post-hoc study of a randomized trial of 4% albumin versus Ringer's acetate for cardiopulmonary bypass priming..
Lee masAbstract Acute kidney injury (AKI) is a complex clinical syndrome with a spectrum of clinical manifestations and outcomes (1); characterized by the deterioration of renal function over a period of..
Lee masAbstract Background Although goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) has been discussed extensively in adult studies, no pediatric indexed oxygen delivery (Do2i) thresholds are universally accepted, and no pediatric..
Lee masAbstract Predictive scoring systems for adult patients receiving extracorporeal membrane oxygenation (ECMO) support for sepsis have not been yet reported. Based on the Chinese Society of ExtraCorporeal Life Support (CSECLS)..
Lee masAbstract Objectives: Previous studies have demonstrated an association between transfusion and increased organ dysfunction. We sought to determine the association between transfusion of blood components (red blood cell [RBC], plasma, platelet,..
Lee masAbstract The study Women in cardiac surgery: A global workforce analysis by Izumi et al. [1] provides important insights into women’s representation in the field of cardiac surgery worldwide and offers a useful benchmark..
Lee masAbstract Background Coronary artery bypass grafting (CABG) is one of the most effective treatments for improving the quality of life in patients with severe coronary artery disease. However, these patients..
Lee masAbstract Background The optimal fluid management strategy for patients undergoing on-pump cardiac surgery was controversial regarding the fluid types. This study aimed to compare the impact of hydroxyethyl starch (HES)..
Lee masAbstract Importance Clinical decision-making in thrombotic disorders is impeded by long-standing uncertainty regarding the magnitude of venous and arterial thrombosis risk associated with low protein S. Population-scale multiomic datasets offer an..
Lee masAbstract Background Acute kidney injury (AKI) is a common and serious complication after coronary artery bypass grafting (CABG), significantly affecting patient outcomes. The triglyceride-glucose (TyG) index, a marker of insulin..
Lee masAbstract Extracorporeal carbon dioxide removal (ECCO2R) is an emerging technique designed to reduce carbon dioxide (CO2) levels in venous blood while enabling lung-protective ventilation or alleviating the work of breathing...
Lee masAbstract “Mechanotransduction” is a term I would use to describe my research topic, and it works perfectly well, as long as the goal is to earn confused looks and immediately..
Lee masAbstract Critically ill patients that require kidney replacement therapy (KRT) are among the most ill and complex patients routinely encountered in the intensive care unit (ICU). Continuous KRT (CKRT) is..
Lee masAbstract Human serum albumin (HSA) is a non-glycosylated, negatively charged, single-chain polypeptide composed of 585 amino acid residues with a relative molecular mass of 66.438 kD. It is synthesized by..
Lee masAbstract Chronic kidney disease (CKD) affects 50% of patients with heart failure. The pathophysiology of CKD in heart failure is proposed to be driven by macrocirculatory hemodynamic changes, including reduced..
Lee masAbstract Background:Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus,..
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