
Abstract
Due to advances in critical care medicine over the past several decades, the number of survivors of critical illness continues to grow despite increased severity of illness (1). There is also growing recognition that these survivors encounter a wide variety of challenges in their recovery. Post-intensive care syndrome (PICS) is defined as new cognitive, physical, or mental health impairments that persist beyond hospitalization in survivors of critical illness. The impacts of PICS-related impairments are far reaching and include inability to return to work, social isolation, financial difficulties, and emotional distress (2,3). As the number of ICU recovery clinics grows, there is promise that regularly evaluating for and treating PICS can improve patient-centered outcomes, although more research is needed in this area (4). For many patients, an ICU discharge is just the beginning of a road to recovery that is often long and laden with many obstacles along the way.
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a form of mechanical life support that can be used to rescue patients who present with cardiogenic shock of varying etiologies. VA-ECMO can also serve as bridge to recovery, transplant, or destination therapy such as a left ventricular assist device (5). The use of VA-ECMO and the number of centers providing it has grown exponentially since 1990 (6). Historically, patients requiring VA-ECMO for cardiogenic shock have an in-hospital mortality approaching 60%, as well as significant rates of ECMO-related adverse events including renal failure, bleeding, vascular complications, and limb ischemia (5–7). The Extracorporeal Life Support Organization (ELSO) registry provides a wealth of data on survival and physical outcomes (6). However, the burden of PICS and long-term patient-centered outcomes in the VA-ECMO survivors has not been well characterized. While survival is undeniably important, most patients and families have expectations beyond discharge from the hospital