Tags Archives: VA-ECMO

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Temporal trends in venoarterial extracorporeal membrane oxygenation and concurrent mechanical circulatory support for cardiogenic shock

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is often combined with other temporary mechanical circulatory support (tMCS) in cardiogenic shock, yet combination-specific outcomes remain poorly defined. We compared temporal trends,..

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Extracorporeal Membrane Oxygenation Combined With Mechanical Thrombectomy Versus Extracorporeal Membrane Oxygenation Alone for High-Risk Pulmonary Embolism: A Systematic Review and…

Abstract Objectives To compare clinical outcomes of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) combined with mechanical thrombectomy (MT) versus VA-ECMO alone in high-risk pulmonary embolism (PE). Design Systematic review and..

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Awake venoarterial extracorporeal membrane oxygenation as a bridge to foetal maturation in severe pulmonary hypertension: a case report

Abstract A 37-year-old patient (gravida 10, para 0–1–8-0) with class III obesity, obstructive sleep apnoea requiring continuous positive airway pressure and previous pulmonary emboli presented at 19 + 6 weeks' gestation with severe..

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Oxygenation Indices with Oxygen Challenge Test in Neonates During VA ECMO

Abstract Objective: To evaluate the response of various oxygenation indices to the oxygen challenge test (OCT), prior to decannulation, in neonates supported with VA ECMO for respiratory indications, and to..

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Upper-Body Versus Femoral Return in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis

Abstract Upper-body peripheral arterial return is used during veno-arterial extracorporeal membrane oxygenation (VA-ECMO), but its clinical tradeoffs versus femoral return are uncertain. We reviewed observational studies comparing upper-body to femoral..

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Extracorporeal Membrane Oxygenation Combined With Embolectomy May Yield Better Outcomes Than Extracorporeal Membrane Oxygenation Alone or With Thrombolysis for Acute…

Abstract Veno-arterial extracorporeal membrane oxygenation (ECMO) is used to support patients with high-risk pulmonary embolism (HR-PE) with cardiogenic shock, but data on mid- and long-term outcomes after reperfusion remain limited...

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A regional partnership model for VA-ECMO initiation and transfer from remote centers using air medical transport

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has become an accepted treatment modality for refractory cardiogenic shock (CS). However, its use is limited to tertiary centers due to resource allocation, education,..

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Impella Versus VA-ECMO in Cardiogenic Shock: An Updated Systematic Review and Meta-Analysis With Exploratory Matched-Cohort Analyses

Abstract Observational studies comparing Impella and venoarterial extracorporeal membrane oxygenation (VA-ECMO) in cardiogenic shock have reported inconsistent findings. We performed an updated systematic review and meta-analysis, with exploratory matched-cohort analyses..

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Venoarterial ECMO management: Clinical considerations

Abstract Venoarterial extracorporeal membrane oxygenation (V-A ECMO) is a technique used to provide short-term circulatory and respiratory support in patients with refractory cardiogenic shock and cardiac arrest who do not..

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Cerebro‑Cardiovascular Coupling During Extracorporeal Membrane Oxygenation Using Cerebral Oxygenation, Doppler Flow, and Echocardiography

Abstract Cerebral injury remains a major contributor to morbidity and mortality in VA‑ECMO patients. Disruption of cerebral autoregulation during extracorporeal support may predispose to neurological damage. This prospective study evaluated..

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Electrical Impedance Tomography Reveals Venoarterial Extracorporeal Membrane Oxygenation Flow-Induced Ventilation-Perfusion Mismatch

Abstract An obese female patient with ischemic cardiomyopathy was placed on venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock after in-hospital cardiac arrest. Despite biventricular recovery by day 3, VA-ECMO..

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Early active normothermia versus no temperature control in a porcine model of extracorporeal cardiopulmonary resuscitation

Abstract Aim Early downward temperature drift is a common event of pre-hospital extracorporeal cardiopulmonary resuscitation (e-CPR), since prehospital extracorporeal membrane oxygenation (VA-ECMO) circuits often lack heat-exchangers. However, whether this core..

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Prosthetic valve thrombosis on venoarterial extracorporeal membrane oxygenation support: Risk factors and outcomes

Abstract Introduction In patients with prior valve replacement requiring venoarterial extracorporeal membrane oxygenation (VA ECMO), there is a risk of prosthetic valve thrombosis (PVT) due to intracardiac stasis. We describe..

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Bilateral radial arterial pressure concordance as a real-time bedside marker of native cardiac recovery during peripheral VA-ECMO weaning

Abstract Patients supported with peripheral femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently face the challenge of determining the optimal timing for weaning trials, as no universally standardized bedside method is..

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Left ventricular unloading during VA-ECMO for refractory cardiogenic shock: a target trial emulation multicenter analysis

Abstract Background: Conflicting data exist regarding the survival benefit of mechanical left ventricular (LV) unloading in patients receiving peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shock (CS). In..

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Clinical and Functional Outcomes Following Repeat VA-ECMO in Adults: A Propensity Score–Matched Comparative Study

Abstract Background/Objectives: Evidence on outcomes after repeat VA-ECMO in adults remains limited. This study aimed to compare survival and post-discharge functional outcomes between adults requiring a second VA-ECMO run and..

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Immunothrombotic Dysregulation in Pediatric Patients Receiving Veno-arterial ECMO After Cardiac Surgery: Insights From Platelet Activation and T Cell Immune Profiling

Abstract Background: Numerous studies have demonstrated that both cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) are often associated with adverse outcomes or immune dysregulation when platelet counts decline during..

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Levosimendan During VA-ECMO for Cardiogenic Shock: An Updated Systematic Review and Meta-analysis Including the LEVOECMO Trial

Abstract Background Levosimendan is often given during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support with the intention of facilitating weaning. The available evidence, however, has been derived largely from nonrandomized studies..

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Outcomes in Obese Adult Venoarterial Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract Historically, extracorporeal membrane oxygenation (ECMO) in critical illness and respiratory failure has been used cautiously in patients with morbid obesity. However, recent data show favorable mortality outcomes for higher..

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Mortality risk model for acute myocardial infarction complicated by cardiogenic shock: development, external validation, and exploratory application in a VA-ECMO…

Abstract Background Acute myocardial infarction complicated by cardiogenic shock (AMI-CS) carries a high risk of in-hospital death. Randomized evidence does not support routine VA-ECMO use in unselected AMI-CS populations. Objective..

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Severe hyperoxia during VA-ECMO promotes oxidative stress and multi-organ injury in an experimental rat model of septic cardiomyopathy

Abstract Background Severe hyperoxia during venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been associated with adverse clinical outcomes in observational studies. However, causal evidence and optimal oxygen targets remain uncertain. Hyperoxia..

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Management of Harlequin syndrome in veno-arterial extracorporeal membrane oxygenation

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA ECMO) provides temporary mechanical circulatory support, primarily for patients with compromised cardiac function. In individuals supported on femoral VA ECMO with concurrent pulmonary..

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Safety of Delayed Venoarterial Extracorporeal Membrane Oxygenation Decannulation in Pediatric Patients

Abstract Background Optimal timing of venoarterial extracorporeal membrane oxygenation (VA-ECMO) decannulation in pediatric patients with congenital or acquired heart disease remains challenging, particularly when myocardial recovery is uncertain. Some centers..

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Mortality-related predictors in patients receiving extracorporeal membrane oxygenation after coronary artery bypass grafting: a retrospective study

Abstract Background This study aimed to evaluate in-hospital mortality and to identify predictors of mortality in coronary artery bypass grafting (CABG) patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. Methods..

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Preoperative Stabilization With Left Atrial Venoarterial Extracorporeal Membrane Oxygenation Before Salvage Valve Surgery in Cardiogenic Shock

Abstract Patients undergoing salvage cardiac surgery experience markedly elevated mortality, often exceeding the risk predicted by the Society of Thoracic Surgeons Predicted Risk of Mortality score. These patients are typically..

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Pragmatic Assessment of VA-ECMO Decannulation Readiness After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract Background Readiness for venoarterial-extracorporeal membrane oxygenation (VA-ECMO) decannulation after extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) remains poorly defined. Objectives The objective of the study was to..

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Brain Death Determination During VA-ECMO After Pediatric Cardiac Surgery: A Case-Based Analysis of the 2023 Unified Consensus

Abstract Background Determination of brain death/death by neurologic criteria (BD/DNC) in patients supported with extracorporeal membrane oxygenation (ECMO) is particularly challenging due to extracorporeal carbon dioxide clearance, which may interfere..

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Transseptal Access System-Assisted Atrial Flow Regulator Implantation for Pediatric Left Ventricular Decompression During VA-ECMO

Abstract Left ventricular (LV) overload is a recognized complication of venoarterial extracorporeal membrane oxygenation (VA-ECMO), but pediatric decompression remains technically challenging and poorly standardized. The atrial flow regulator (AFR) (Occlutech) is..

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Levosimendan for Weaning from VA-ECMO: Two Trials, Two Timings

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for providing adequate organ support in cardiogenic shock. While the intervention provides circulatory and respiratory support in the critical stage, it..

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Mortality-related predictors in patients receiving extracorporeal membrane oxygenation after coronary artery bypass grafting: a retrospective study

Abstract Background This study aimed to evaluate in-hospital mortality and to identify predictors of mortality in coronary artery bypass grafting (CABG) patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. Methods..

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