Tags Archives: ecmo

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Continuing Extracorporeal Membrane Oxygenation Without Potential Recovery, Transplant, or Device

Abstract The use of extracorporeal membrane oxygenation Q4 (ECMO) as a temporary bridge to recovery, transplant, or durable device implantation is widely accepted. Major unease remains for patients already receiving..

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Extracorporeal Multiorgan Support During Prone Positioning in Severe ARDS: A Physiologic Proof-of-Concept Study

Abstract Background:   Prone positioning and lung-protective ventilation are key components of the management of moderate-to-severe acute respiratory distress syndrome (ARDS). However, protective ventilation may be limited by refractory hypercapnia,..

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Comprehensive Longitudinal Cytokine Profiling and their Associations with Distinct Immunologic Phenotypes and Outcomes: A Prospective Clinical Study in Venovenous ECMO

Abstract INTRODUCTION: Venovenous extracorporeal membrane oxygenation (VV ECMO) is a life‑saving intervention commonly used for severe and refractory respiratory failure. However, patient management and outcomes in this setting remain challenging..

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Gastrointestinal complications in patients supported by venoarterial extracorporeal membrane oxygenation: Pathophysiological mechanisms and clinical implications

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving therapy for refractory shock; however, gastrointestinal (GI) complications have been reported in up to 50% of these patients and contribute substantially..

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Extracorporeal Life Support in ARDS: Lessons from Maternal–Fetal Physiology

Abstract Despite decades of clinical experience, the physiological rationale for extracorporeal life support (ECLS) in acute respiratory distress syndrome (ARDS) remains incompletely defined. Existing trials have primarily evaluated ECLS as..

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Antithrombin Activity and Inflammatory Phenotypes as Predictors of Outcome in Venovenous Extracorporeal Membrane Oxygenation

Abstract Antithrombin (AT) depletion is common in critical illness, and during venovenous extracorporeal membrane oxygenation (VV ECMO), blood–surface interactions further amplify coagulation and inflammation cascades. The prognostic value of baseline..

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Out-of-bed mobility during venovenous ECMO among patients listed for lung transplantation: A descriptive single-center cohort study

Abstract Purpose Out-of-bed (OOB) mobility is often expected of patients bridged to lung transplantation (LTx) on venovenous (VV) extracorporeal membrane oxygenation (ECMO), but the course of listed patients who never..

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Post-decannulation management of residual ECMO circuit blood: a national cross-sectional survey in China

Abstract Background Post-decannulation management of residual extracorporeal membrane oxygenation (ECMO) circuit blood is an under-standardized issue in critical care and perioperative patient blood management. Whether residual circuit blood should be..

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Extracorporeal Membrane Oxygenation Outside the Operating Room in Neonates and Infants

Abstract Objectives Long-term outcomes of emergent extracorporeal membrane oxygenation (ECMO) initiated outside the operating room remain poorly defined. We evaluated long-term outcomes after emergent ECMO support outside the operating room..

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Early Metabolomic Changes During Extracorporeal Membrane Oxygenation Are Associated with Subsequent Acute Brain Injury

Abstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..

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Challenges and opportunities in ECMO monitoring: A mixed-methods appraisal

Abstract Extracorporeal membrane oxygenation (ECMO) provides heart/lung support for critically ill patients. While advances in research have improved the overall design and performance of ECMO circuits, complications such as hemolysis..

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Postmarket Surveillance of ECMO Pump and Control Console Malfunctions: Insights from the MAUDE Database

Abstract Failure of extracorporeal membrane oxygenation (ECMO) circuit components can precipitate abrupt hemodynamic or respiratory collapse; however, the evidence linking specific component malfunctions to patient harm remains sparse, and device-specific..

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Real-world outcomes of unfractionated heparin plus antithrombin concentrate versus bivalirudin in adult patients undergoing extracorporeal membrane oxygenation

Abstract Background: Extracorporeal membrane oxygenation (ECMO) provides life support to patients undergoing cardiopulmonary surgeries when other interventions are ineffective. Unfractionated heparin (UFH) is routinely used during ECMO due to the..

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Medical Versus Surgical Respiratory Extracorporeal Membrane Oxygenation Candidacy Processes Are Similar

Abstract Venovenous extracorporeal membrane oxygenation (VV ECMO) candidacy decision-making processes vary within and between centers. An underexplored potential contributor to this variability is the care model. Fundamental differences in infrastructure,..

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Extracorporeal membrane oxygenation for life-threatening measles in children: a case series

Abstract Measles is resurgent worldwide, and although vaccine-preventable, severe disease can progress to cardiorespiratory failure refractory to conventional support. This study aimed to determine whether extracorporeal membrane oxygenation (ECMO) is..

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Tandem ECMO/CRRT medical nutrition therapy clinical practice points: A literature review and Delphi consensus on clinical practice

Abstract Background Patients who undergo tandem extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) have a high risk of metabolic disturbances, malnutrition, and fluid imbalances. ECMO/CRRT tandem therapy..

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The Early Assessment of a Newly Developed Maglev Extracorporeal Mechanical Oxygenation System : 14 Day In Vivo Study Report

Abstract Extracorporeal membrane oxygenation (ECMO) is standard for cardiogenic shock, but outcomes remain limited. The BreathMo adult ECMO system with a maglev pump and a low-pressure drop oxygenator was developed...

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A porous antioxidant membrane for ECMO: Remodeling oxidative stress response patterns and enhancing blood oxygenation efficiency

Abstract Oxidative stress injury is a critical complication during long-term extracorporeal membrane oxygenation (ECMO) support and is further aggravated in critically ill patients with diabetic metabolic comorbidities. Nevertheless, conventional ECMO..

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Combining Renal Replacement Therapy With ECMO: A Scoping Review of Circuit Configurations

What the review examined The investigators searched PubMed, the Cochrane Library, Web of Science, Embase, and ClinicalTrials.gov, with a final search on February 9, 2026. The review followed JBI and..

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Pharmacology of vasopressors and inotropes during extracorporeal membrane oxygenation

Abstract Background This review aims to provide a concise summary of hemodynamic considerations and the pharmacology and current evidence of vasoactive support, including inotropes and vasopressors, during extracorporeal membrane oxygenation..

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Best Evidence Summary of Brain Function Monitoring and Management in Patients Receiving Extracorporeal Membrane Oxygenation

Abstract Background Neurological complications are among the most serious adverse events in patients receiving extracorporeal membrane oxygenation (ECMO). Brain injury during ECMO is associated with increased mortality, long-term neurological deficits..

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Impact of side hole design of drainage cannulas on flow velocity and predilection sites for low-flow areas in veno-venous ECMO…

Abstract Background Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) (VV-ECMO) and Veno-Artial Extracorporeal Membrane Oxygenation (VA-ECMO) have become evidence-based therapy options for patients with most severe heart and/or lung failure. Cannulas continue..

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How To Do It: Pediatric Extracorporeal Membrane Oxygenation (ECMO)

Abstract Extracorporeal membrane oxygenation (ECMO) is an invaluable tool in cardiac surgery. In pediatric patients, it is almost exclusively deployed by congenital cardiac surgeons who are sufficiently trained. Pediatric ECMO..

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Monitoring Cerebral Perfusion during the Initiation of Veno-venous Extracorporeal Membrane Oxygenation

Abstract Support with veno-venous extracorporeal membrane oxygenation (VV-ECMO) can be considered for patients with severe (combined) hypoxemia and hypercapnia. By adjusting sweep gas flow (SGF), blood oxygenation and correction of..

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Temporal trends in venoarterial extracorporeal membrane oxygenation and concurrent mechanical circulatory support for cardiogenic shock

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is often combined with other temporary mechanical circulatory support (tMCS) in cardiogenic shock, yet combination-specific outcomes remain poorly defined. We compared temporal trends,..

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Use of extracorporeal membrane oxygenation (ECMO) in Spain as a method of organ preservation for transplantation

Abstract Donation following the confirmation of death based on circulatory criteria has proven to be a valuable strategy for increasing the availability of organs for transplantation. However, the standard super-rapid..

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The Role of Regret in Extracorporeal Membrane Oxygenation Candidacy Decision-Making

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) candidacy decisions are made under substantial uncertainty and are inconsistent. With a team including economist decision-scientists, we applied Regret Theory to hypothesize..

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Core components of transitional care for ECMO survivors after ICU discharge: a three-round modified Delphi study

Abstract Background Survivors of extracorporeal membrane oxygenation (ECMO) may experience persistent physical, cognitive, psychological, social, and quality-of-life impairments after intensive care unit (ICU) discharge. However, the core components of early..

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Extracorporeal Membrane Oxygenation Combined With Mechanical Thrombectomy Versus Extracorporeal Membrane Oxygenation Alone for High-Risk Pulmonary Embolism: A Systematic Review and…

Abstract Objectives To compare clinical outcomes of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) combined with mechanical thrombectomy (MT) versus VA-ECMO alone in high-risk pulmonary embolism (PE). Design Systematic review and..

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Extracorporeal life support in adult critically ill patients: mechanisms of benefit in respiratory and cardiac failure

Abstract Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respiratory failure refractory to conventional measures. Its application has broadened across a wide spectrum..

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