Abstract The use of extracorporeal membrane oxygenation Q4 (ECMO) as a temporary bridge to recovery, transplant, or durable device implantation is widely accepted. Major unease remains for patients already receiving..
Read MoreAbstract Background: Prone positioning and lung-protective ventilation are key components of the management of moderate-to-severe acute respiratory distress syndrome (ARDS). However, protective ventilation may be limited by refractory hypercapnia,..
Read MoreAbstract INTRODUCTION: Venovenous extracorporeal membrane oxygenation (VV ECMO) is a life‑saving intervention commonly used for severe and refractory respiratory failure. However, patient management and outcomes in this setting remain challenging..
Read MoreAbstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving therapy for refractory shock; however, gastrointestinal (GI) complications have been reported in up to 50% of these patients and contribute substantially..
Read MoreAbstract Despite decades of clinical experience, the physiological rationale for extracorporeal life support (ECLS) in acute respiratory distress syndrome (ARDS) remains incompletely defined. Existing trials have primarily evaluated ECLS as..
Read MoreAbstract Antithrombin (AT) depletion is common in critical illness, and during venovenous extracorporeal membrane oxygenation (VV ECMO), blood–surface interactions further amplify coagulation and inflammation cascades. The prognostic value of baseline..
Read MoreAbstract Purpose Out-of-bed (OOB) mobility is often expected of patients bridged to lung transplantation (LTx) on venovenous (VV) extracorporeal membrane oxygenation (ECMO), but the course of listed patients who never..
Read MoreAbstract Background Post-decannulation management of residual extracorporeal membrane oxygenation (ECMO) circuit blood is an under-standardized issue in critical care and perioperative patient blood management. Whether residual circuit blood should be..
Read MoreAbstract Objectives Long-term outcomes of emergent extracorporeal membrane oxygenation (ECMO) initiated outside the operating room remain poorly defined. We evaluated long-term outcomes after emergent ECMO support outside the operating room..
Read MoreAbstract Coronary artery bypass grafting (CABG) utilizing cardiopulmonary bypass (CPB) remains a cornerstone of treatment for advanced multivessel coronary artery disease. During the ischemic period, myocardial cells become injured and..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) provides heart/lung support for critically ill patients. While advances in research have improved the overall design and performance of ECMO circuits, complications such as hemolysis..
Read MoreAbstract Failure of extracorporeal membrane oxygenation (ECMO) circuit components can precipitate abrupt hemodynamic or respiratory collapse; however, the evidence linking specific component malfunctions to patient harm remains sparse, and device-specific..
Read MoreAbstract Background: Extracorporeal membrane oxygenation (ECMO) provides life support to patients undergoing cardiopulmonary surgeries when other interventions are ineffective. Unfractionated heparin (UFH) is routinely used during ECMO due to the..
Read MoreAbstract Venovenous extracorporeal membrane oxygenation (VV ECMO) candidacy decision-making processes vary within and between centers. An underexplored potential contributor to this variability is the care model. Fundamental differences in infrastructure,..
Read MoreAbstract Measles is resurgent worldwide, and although vaccine-preventable, severe disease can progress to cardiorespiratory failure refractory to conventional support. This study aimed to determine whether extracorporeal membrane oxygenation (ECMO) is..
Read MoreAbstract Background Patients who undergo tandem extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) have a high risk of metabolic disturbances, malnutrition, and fluid imbalances. ECMO/CRRT tandem therapy..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is standard for cardiogenic shock, but outcomes remain limited. The BreathMo adult ECMO system with a maglev pump and a low-pressure drop oxygenator was developed...
Read MoreAbstract Oxidative stress injury is a critical complication during long-term extracorporeal membrane oxygenation (ECMO) support and is further aggravated in critically ill patients with diabetic metabolic comorbidities. Nevertheless, conventional ECMO..
Read MoreWhat the review examined The investigators searched PubMed, the Cochrane Library, Web of Science, Embase, and ClinicalTrials.gov, with a final search on February 9, 2026. The review followed JBI and..
Read MoreAbstract Background This review aims to provide a concise summary of hemodynamic considerations and the pharmacology and current evidence of vasoactive support, including inotropes and vasopressors, during extracorporeal membrane oxygenation..
Read MoreAbstract Background Neurological complications are among the most serious adverse events in patients receiving extracorporeal membrane oxygenation (ECMO). Brain injury during ECMO is associated with increased mortality, long-term neurological deficits..
Read MoreAbstract Background Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) (VV-ECMO) and Veno-Artial Extracorporeal Membrane Oxygenation (VA-ECMO) have become evidence-based therapy options for patients with most severe heart and/or lung failure. Cannulas continue..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is an invaluable tool in cardiac surgery. In pediatric patients, it is almost exclusively deployed by congenital cardiac surgeons who are sufficiently trained. Pediatric ECMO..
Read MoreAbstract Support with veno-venous extracorporeal membrane oxygenation (VV-ECMO) can be considered for patients with severe (combined) hypoxemia and hypercapnia. By adjusting sweep gas flow (SGF), blood oxygenation and correction of..
Read MoreAbstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is often combined with other temporary mechanical circulatory support (tMCS) in cardiogenic shock, yet combination-specific outcomes remain poorly defined. We compared temporal trends,..
Read MoreAbstract Donation following the confirmation of death based on circulatory criteria has proven to be a valuable strategy for increasing the availability of organs for transplantation. However, the standard super-rapid..
Read MoreAbstract Background Veno-venous extracorporeal membrane oxygenation (VV ECMO) candidacy decisions are made under substantial uncertainty and are inconsistent. With a team including economist decision-scientists, we applied Regret Theory to hypothesize..
Read MoreAbstract Background Survivors of extracorporeal membrane oxygenation (ECMO) may experience persistent physical, cognitive, psychological, social, and quality-of-life impairments after intensive care unit (ICU) discharge. However, the core components of early..
Read MoreAbstract Objectives To compare clinical outcomes of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) combined with mechanical thrombectomy (MT) versus VA-ECMO alone in high-risk pulmonary embolism (PE). Design Systematic review and..
Read MoreAbstract Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respiratory failure refractory to conventional measures. Its application has broadened across a wide spectrum..
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