Tags Archives: ecmo

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Comparative Performance of Oxygenators for Extracorporeal Membrane Oxygenation in Adults: A Retrospective Analysis

Abstract Extracorporeal membrane oxygenation (ECMO) is a vital therapy for patients with severe cardiac and pulmonary failure. Despite technological advances, oxygenator dysfunction remains common, yet comparative clinical data across devices..

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Extracorporeal membrane oxygenation in pediatric cardiac surgery: retrospective survival analysis

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving therapeutic modality in children. Outcome is multifactorial with debates regarding predictors of weaning success and mortality. Objective To explore predictors of..

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Immunothrombotic Dysregulation in Pediatric Patients Receiving Veno-arterial ECMO After Cardiac Surgery: Insights From Platelet Activation and T Cell Immune Profiling

Abstract Background: Numerous studies have demonstrated that both cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) are often associated with adverse outcomes or immune dysregulation when platelet counts decline during..

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Circuit-Directed Nitric Oxide in Anticoagulation-Contraindicated Adult Extracorporeal Membrane Oxygenation: A Single-Center Case Series

Abstract Oxygenator thrombosis is a major complication during extracorporeal membrane oxygenation (ECMO), but systemic anticoagulation may be contraindicated by active hemorrhage, recent surgery, intracranial injury, or severe coagulopathy. Circuit-directed nitric..

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Levosimendan During VA-ECMO for Cardiogenic Shock: An Updated Systematic Review and Meta-analysis Including the LEVOECMO Trial

Abstract Background Levosimendan is often given during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support with the intention of facilitating weaning. The available evidence, however, has been derived largely from nonrandomized studies..

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Protocol and Statistical Analysis Plan for the ECMO-Free Trial

Abstract Background Decannulation from venovenous extracorporeal membrane oxygenation (ECMO) at the earliest safe opportunity would be expected to improve patient outcomes. Currently, the manner in which clinicians liberate patients from..

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Center Experience, Learning Curves, Run Durations, and Outcomes in Venovenous Extracorporeal Membrane Oxygenation

Abstract Background The expanding availability of venovenous extracorporeal membrane oxygenation (ECMO) and the increasing frequency of prolonged ECMO runs challenge standard definitions of center experience based solely on patient counts...

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Outcomes in Obese Adult Venoarterial Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract Historically, extracorporeal membrane oxygenation (ECMO) in critical illness and respiratory failure has been used cautiously in patients with morbid obesity. However, recent data show favorable mortality outcomes for higher..

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Increasing utilization of extracorporeal membrane oxygenation and its association with venous thromboembolism following lung transplant

Abstract Background Venous thromboembolism (VTE) is a common complication following lung transplantation, and perioperative extracorporeal membrane oxygenation (ECMO) use has increased substantially over time. The relationship between ECMO exposure and..

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Extracorporeal membrane oxygenation may prevent preterm cerebral atrophy in survivors of acute respiratory distress syndrome: a pilot trial

Abstract BACKGROUND: Individuals who survive acute respiratory distress syndrome (ARDS) often face prolonged cognitive impairments. Comparable consequences have been observed in chronic hypoxic conditions, like COPD and obstructive sleep apnea..

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A Structured Checklist for Bedside Rounds on Extracorporeal Membrane Oxygenation Patients

Abstract Patients supported with extracorporeal membrane oxygenation (ECMO) represent a uniquely challenging population. These patients require specific interventions, such as repeated circuit and lower extremity perfusion assessments, anticoagulation management, frequent..

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Revolutionizing Accelerated Percutaneous Initiation and Deployment of ECPR (RAPID ECPR): Single-Center Process and Outcomes

Abstract Objectives Recent randomized controlled trials comparing extracorporeal cardiopulmonary resuscitation (ECPR) with conventional cardiopulmonary resuscitation (CCPR) reveal mixed outcomes; however, current data support an association between ECPR and neurologically intact..

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Awake paediatric venovenous extracorporeal membrane oxygenation case report: Feasibility of PICUStars Liberation Bundles to achieve early mobilisation

Abstract Awake extracorporeal membrane oxygenation (aECMO) has emerged as a strategy to minimise physical and neurocognitive complications of a prolonged intensive care admission. However, the safety and implementation in critically..

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Meropenem Exposure During Extracorporeal Membrane Oxygenation: What Should Intensivists Know? A Scoping Review

Abstract Background Extracorporeal membrane oxygenation (ECMO) is increasingly used in adults with severe respiratory and/or cardiac failure. Because ECMO may alter drug pharmacokinetics (PK), optimizing antimicrobial dosing in this population..

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Mortality risk model for acute myocardial infarction complicated by cardiogenic shock: development, external validation, and exploratory application in a VA-ECMO…

Abstract Background Acute myocardial infarction complicated by cardiogenic shock (AMI-CS) carries a high risk of in-hospital death. Randomized evidence does not support routine VA-ECMO use in unselected AMI-CS populations. Objective..

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From Pump to Neck: A Focused Review of Mechanical Complications in Extracorporeal Membrane Oxygenation (ECMO) Circuits

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving modality, yet it carries inherent risks of device-related adverse events. This manuscript is a focused review of ECMO circuit mechanics, monitoring, and..

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Severe hyperoxia during VA-ECMO promotes oxidative stress and multi-organ injury in an experimental rat model of septic cardiomyopathy

Abstract Background Severe hyperoxia during venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been associated with adverse clinical outcomes in observational studies. However, causal evidence and optimal oxygen targets remain uncertain. Hyperoxia..

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Management of Harlequin syndrome in veno-arterial extracorporeal membrane oxygenation

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA ECMO) provides temporary mechanical circulatory support, primarily for patients with compromised cardiac function. In individuals supported on femoral VA ECMO with concurrent pulmonary..

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Impact of cannula configuration on efficiency and mechanical ventilation intensity during venovenous ECMO

Abstract Background The efficiency of venovenous extracorporeal membrane oxygenation (VV ECMO) may be influenced by cannula configuration, potentially affecting oxygenation and the ability to apply ultra-protective ventilation in severe ARDS...

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The extracorporeal cardiopulmonary resuscitation outcomes database

Abstract Background Cardiac arrest impacts more than 500,000 people in the United States annually. Overall, cardiac arrest, particularly when it occurs outside of a hospital, is associated with low rates..

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Mortality-related predictors in patients receiving extracorporeal membrane oxygenation after coronary artery bypass grafting: a retrospective study

Abstract Background This study aimed to evaluate in-hospital mortality and to identify predictors of mortality in coronary artery bypass grafting (CABG) patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. Methods..

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Designing a Cardiac Arrest System That Includes Extracorporeal Cardiopulmonary Resuscitation: A Contemporary Review

Abstract Extracorporeal cardiopulmonary resuscitation for refractory out‐of‐hospital cardiac arrest is increasingly used, with survival rates up to ≈30% reported in select highly organized systems, although outcomes vary widely across programs...

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Preoperative Stabilization With Left Atrial Venoarterial Extracorporeal Membrane Oxygenation Before Salvage Valve Surgery in Cardiogenic Shock

Abstract Patients undergoing salvage cardiac surgery experience markedly elevated mortality, often exceeding the risk predicted by the Society of Thoracic Surgeons Predicted Risk of Mortality score. These patients are typically..

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Pragmatic Assessment of VA-ECMO Decannulation Readiness After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract Background Readiness for venoarterial-extracorporeal membrane oxygenation (VA-ECMO) decannulation after extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) remains poorly defined. Objectives The objective of the study was to..

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Brain Death Determination During VA-ECMO After Pediatric Cardiac Surgery: A Case-Based Analysis of the 2023 Unified Consensus

Abstract Background Determination of brain death/death by neurologic criteria (BD/DNC) in patients supported with extracorporeal membrane oxygenation (ECMO) is particularly challenging due to extracorporeal carbon dioxide clearance, which may interfere..

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Transseptal Access System-Assisted Atrial Flow Regulator Implantation for Pediatric Left Ventricular Decompression During VA-ECMO

Abstract Left ventricular (LV) overload is a recognized complication of venoarterial extracorporeal membrane oxygenation (VA-ECMO), but pediatric decompression remains technically challenging and poorly standardized. The atrial flow regulator (AFR) (Occlutech) is..

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Extracorporeal Membrane Oxygenation Ethics

Abstract Topic Importance Extracorporeal membrane oxygenation (ECMO) is a relatively novel, intensive medical intervention. It is known to raise important yet unsettled ethical concerns. Overview We established the ECMO Ethics..

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A Novel Method for Predicting Recirculation by Sweep-Gas Control in Extracorporeal Membrane Oxygenation

Abstract Purpose: Recirculation is a critical issue in veno-venous extracorporeal membrane oxygenation (VV ECMO). We propose a novel method for estimating the recirculation ratio using temporary sweep-gas control. Methods: A circuit simulating..

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The Role of Recirculation-Guided Blood Flow Adjustment in Venovenous Extracorporeal Membrane Oxygenation: A Pilot Study

Abstract Recirculation reduces the efficiency of venovenous extracorporeal membrane oxygenation (V-V ECMO), but patient-specific determinants of recirculation and the feasibility of recirculation-guided flow adjustment are not well defined. In this..

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Neonatal enterovirus myocarditis outcomes following extracorporeal membrane oxygenation (NEMO-ECMO): An ELSO registry analysis

Abstract Background Neonates with enterovirus myocarditis may require extracorporeal membrane oxygenation (ECMO). The contemporary prognosis and risk factors for mortality of neonates with enterovirus myocarditis supported on ECMO is unknown...

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