Archives

thumbnail
0 comment

Clinical correlates for major bleeding during veno-arterial extracorporeal membrane oxygenation support: a time-dependent perspective

Abstract Background Major bleeding is a common and serious complication of veno-arterial extracorporeal membrane oxygenation (VA ECMO). Current perspectives on bleeding risk fail to reflect dynamic changes over time in..

Read More
thumbnail
0 comment

Continuous vs pulsatile arterial cannula flow for venoarterial extracorporeal membrane oxygenation: A multiscale computational fluid dynamics analysis

Abstract Background and Objective Venoarterial extracorporeal membrane oxygenation (VA ECMO) circuits typically utilise a continuous flow (CF) of blood to support patients suffering from refractory cardiorespiratory dysfunction. Pulsatile flow (PF)..

Read More
thumbnail
0 comment

Semi-Empirical Model to Predict Blood Flow in an Extracorporeal Respiratory Support Circuit Driven by Ventricular Assist Devices

Abstract Despite increasing clinical interest in ambulatory extracorporeal membrane oxygenation (ECMO), its equipment is not optimally designed for portability. Blood pumps are too heavy for ambulation, as the lightest system..

Read More
thumbnail
0 comment

Acid–Base Status During Venoarterial Extracorporeal Membrane Oxygenator Support in Patients With Cardiogenic Shock

Abstract Background The prognostic significance of an adverse acid–base milieu despite venoarterial extracorporeal membrane oxygenation support in patients with cardiogenic shock remains poorly defined. We examined metabolic and respiratory disturbances..

Read More
thumbnail
0 comment

Standardization of In Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development

Abstract Extracorporeal life support (ECLS) technology has witnessed remarkable advancements during the last decades. However, further research and development of devices are required to increase, for example, performance-efficiency, hemocompatibility, and..

Read More
thumbnail
0 comment

A Landmark Case in ECMO-Supported Bridge-to-Transplant Care

A Landmark Case in ECMO-Supported Bridge-to-Transplant Care  Extracorporeal membrane oxygenation (ECMO) has always been a therapy defined by its ability to buy time; time for a heart to recover, for lungs..

Read More
thumbnail
0 comment

Effect of ECMO Flow Variations on Pulmonary Capillary Wedge Pressure in Patients With Cardiogenic Shock

Abstract Background The hemodynamic effects of femoro-femoral venoarterial (VA) extracorporeal membrane oxygenation (ECMO) on pulmonary capillary wedge pressure (PCWP) remain poorly defined. High ECMO flow is believed to increase PCWP..

Read More
thumbnail
0 comment

Evaluation of bivalirudin-based anticoagulation for extracorporeal membrane oxygenation, including patients with COVID-19

Abstract Background: Although unfractionated heparin (UFH) has traditionally been used for anticoagulation during extracorporeal membrane oxygenation (ECMO), bivalirudin may be preferred due to fewer complications. A prior medication use evaluation..

Read More
thumbnail
0 comment

Clinician Perspectives on the Extracorporeal Membrane Oxygenation Decision-Making Process

Abstract Importance  Venovenous extracorporeal membrane oxygenation (VV ECMO) is a resource-intensive, life-sustaining technology to support patients with severe refractory respiratory failure. Its precise indications and contraindications are not standardized, and expert..

Read More
thumbnail
0 comment

Management of the environment and patient care using extracorporeal membrane oxygenation: A scoping review

Abstract Introduction The use of strategies planned for the environment and care of adult patients undergoing Extracorporeal Membrane Oxygenation allows for better assistance from the multidisciplinary team to this individual..

Read More
thumbnail
0 comment

Nanoconjugated anticoagulant coating with blood repellency for extracorporeal circulation in cardiothoracic surgery

Abstract Coating strategies play a pivotal role in anticoagulation management during extracorporeal circulation. While heparin-based coatings remain the most widely used, their limited anticoagulant efficacy may lead to adverse events..

Read More
thumbnail
0 comment

The Role of Extracorporeal Membrane Oxygenation in Airway Surgery: Experience From a French Referral Centre for Tracheobronchial Diseases Get access…

Abstract Objectives In complex airway surgery and high-risk rigid bronchoscopy, conventional ventilation may be unsafe or impossible. We report our experience using veno-venous extracorporeal membrane oxygenation (VV-ECMO) as respiratory support...

Read More
thumbnail
0 comment

Simple and reliable method for predicting extracorporeal membrane oxygenation flow rates and circuit pressures

Abstract Background Venovenous extracorporeal membrane oxygenation (ECMO) is essential for patients with severe respiratory failure who do not respond to conventional mechanical ventilation. Adequate ECMO flow and safe circuit pressure..

Read More
thumbnail
0 comment

Noninvasive Predictive Model for Rapid Hemodynamic Optimization During Mechanical Circulatory Support

Abstract Mechanical circulatory support (MCS) devices are standard therapy for advanced heart failure, but modern systems lack standardized methods for setting critical parameters such as rotational speed and flow rate...

Read More
thumbnail
0 comment

Integration Health Guides Hospitals in Advanced Circulatory Support Through ECMO and Perfusion Educational Resources

Abstract Hospitals seeking to implement complex technologies like extracorporeal membrane oxygenation (ECMO) now have practical roadmaps thanks to Integration Health’s effort to provide guidance drawn from decades of clinical and..

Read More
thumbnail
0 comment

Prolonged Extracorporeal Membrane Oxygenation Without Systemic Anticoagulation in Sheep

Abstract Clinically significant bleeding is a common complication of extracorporeal membrane oxygenation (ECMO), with bleeding observed in upwards of 40% of patients. Bleeding is strongly associated with systemic anticoagulation, which..

Read More
thumbnail
0 comment

Balancing flow and filtration: AKI during ECMO

Abstract Acute Kidney Injury (AKI) cannot be viewed as a mere complication in critically ill patients who require extracorporeal membrane oxygenation (ECMO). Rather, it is being increasingly recognized as an..

Read More
thumbnail
0 comment

Venoarterial Extracorporeal Membrane Oxygenation Drainage Cannula Choice Impacts Flow Dynamics and Thrombosis Risk: A Computational Analysis

Abstract The drainage cannula in a venoarterial extracorporeal membrane oxygenation (VA ECMO) circuit transfers venous blood from the patient to a pump. However, drainage cannulas are prone to thrombosis, leading..

Read More
thumbnail
0 comment

Net Prolongation of Life in Advanced Heart Failure: An Intentional Strategy of Durable LVAD Therapy Followed by Heart Transplantation

Abstract Heart transplantation (HT) and durable left ventricular assist device (LVAD) support are established surgical treatment options for patients with end-stage systolic heart failure (HF) and/or nonrecoverable cardiogenic shock. HT..

Read More
thumbnail
0 comment

Association of VA-ECMO support and long-term quality of life after post-cardiotomy cardiogenic shock: experience from a prospective cohort

Abstract Post-cardiotomy cardiogenic shock (PC-CS) affects 2–6% of cardiac surgery patients. While survival rates keep improving, 40% of intensive care (ICU) survivors experience a “post-intensive care syndrome”, encompassing physical, cognitive,..

Read More
thumbnail
0 comment

Evidence-based guidelines for the use of extracorporeal membrane oxygenation in Australia and New Zealand using GRADE methodology series part 1:…

Abstract We aim to provide evidence-based clinical practice guidelines for the use of VV ECMO in adult patients across Australia and New Zealand. Developed by a multidisciplinary panel of clinicians..

Read More
thumbnail
0 comment

Vasopressor Requirements after Initiation of Venovenous Extracorporeal Membrane Oxygenation in Patients with Severe Respiratory Failure

Abstract Background Patients with severe respiratory failure frequently suffer from concomitant haemodynamic compromise. By correcting respiratory acidosis and permitting reduced mechanical ventilation pressures, venovenous extracorporeal membrane oxygenation (V-V ECMO) may..

Read More
thumbnail
0 comment

Extracorporeal Carbon Dioxide Removal in Acute Respiratory Distress Syndrome: Physiologic Rationale and Phenotype-Based Perspectives

Abstract Acute respiratory distress syndrome (ARDS) is a major cause of morbidity and mortality despite decades of progress in ventilatory support. Mechanical ventilation, while essential for oxygenation, may exacerbate lung..

Read More
thumbnail
0 comment

Socioeconomic status and ECMO outcomes in severe ARDS

Abstract Background Socioeconomic inequalities have been associated with adverse outcomes in critically ill COVID-19 patients. Whether these disparities extend to the most severe ARDS patients treated with ECMO, regardless of..

Read More
thumbnail
0 comment

Comparison between regional citrate anticoagulation and systemic heparin anticoagulation in patients undergoing continuous renal replacement therapy and venoarterial extracorporeal membrane…

Abstract Introduction Regional citrate anticoagulation (RCA) is the recommended first-line strategy for continuous renal replacement therapy (CRRT) circuits. Acute kidney injury is common in patients undergoing venoarterial extracorporeal membrane oxygenation..

Read More
thumbnail
0 comment

Emergency cesarean section in pregnant women with severe pulmonary hypertension: the potential role of extracorporeal life support

Abstract BACKGROUND: The aim of this study was to present our institutional experience with periprocedural management of emergency cesarean section (CS) operations and maternal and fetal cardiac complications in pregnant..

Read More
thumbnail
0 comment

The Impact of Hemolytic Processes Due to Extracorporeal Support Therapy on the Serum Concentration of the Neuronal Marker Protein NSE

Abstract Neuron-specific enolase (NSE) is a marker used to assess neurological impairment. Notwithstanding, the release of NSE into the circulation can also originate from erythrocytes and thrombocytes, signifying that even..

Read More
thumbnail
0 comment

Inguinal Cannulation for Establishing Extracorporeal Circulation in Adult Porcine Model

Abstract Due to the similar size ratios, adult porcine models are suitable for cardiovascular and circulatory physiology studies on extracorporeal circulation. As standard, the connection to the cardiopulmonary bypass (CBP)..

Read More
thumbnail
0 comment

Multi-modal pediatric critical care datamart for extracorporeal support prediction and decision support

Abstract Objectives To develop a multimodal pediatric critical care datamart supporting predictive modeling and decision support tool development, integrating high-resolution physiologic and clinical data and future clinical deployment. Materials and..

Read More
thumbnail
0 comment

Multimodal characterization of flow-induced thrombus initiation and growth in extracorporeal membrane oxygenation

Abstract In cases of severe cardiopulmonary failure, extracorporeal membrane oxygenation (ECMO) may be temporarily used as a life-saving support for cardiac and/or lung function. Operating under non-physiological flow conditions, characterized..

Read More